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LDL too low???

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General fitness, health and nutrition
Published
21 October 2003
Last activity
1 November 2003
Original author
Preston Rich
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  1. I am a 62 yr. old T2 diabetic controlled w/1000 mg. lipitor bid. I'm
    also on a beta blocker w/HCTZ and atorvastatin (Lipitor 10 mg). My
    latest serum tests came in at:

    TC 126
    TG 167
    HDL 50
    LDL 42
    vLDL 33

    What are the consequences of such a low TC and LDL? Should I consider
    coming off the statin and go on a fibrate like gemfibrozil to better
    target my trigs (which sometimes go up to 350-400 w/my metabolic
    syndrome)?

    -Preston

  2. [email hidden] (Preston Rich) wrote in part:

    Quoted message said:

    w/1000 mg. lipitor bid. I'm
    also on ... atorvastatin (Lipitor 10 mg)

    Huh?
    --
    Jim Chinnis Warrenton, Virginia, USA

  3. Preston Rich said:

    I am a 62 yr. old T2 diabetic controlled w/1000 mg. lipitor bid. I'm
    also on a beta blocker w/HCTZ and atorvastatin (Lipitor 10 mg). My
    latest serum tests came in at:

    TC 126
    TG 167
    HDL 50
    LDL 42
    vLDL 33

    What are the consequences of such a low TC and LDL?

    None known.

    Quoted message said:

    Should I consider
    coming off the statin and go on a fibrate like gemfibrozil to better
    target my trigs (which sometimes go up to 350-400 w/my metabolic
    syndrome)?

    Would suggest you discuss this with your doctor.

    --
    Dr. Andrew B. Chung, MD/PhD
    Board-Certified Cardiologist
    http://www.heartmdphd.com/

  4. Sorry. Meant to say "...controlled w/1000 mg. _Metformin_ bid."

    [email hidden] (Preston Rich) wrote in message news:<[email hidden]>...

    Quoted message said:

    I am a 62 yr. old T2 diabetic controlled w/1000 mg. lipitor bid. I'm
    also on a beta blocker w/HCTZ and atorvastatin (Lipitor 10 mg). My
    latest serum tests came in at:

    TC 126
    TG 167
    HDL 50
    LDL 42
    vLDL 33

    What are the consequences of such a low TC and LDL? Should I consider
    coming off the statin and go on a fibrate like gemfibrozil to better
    target my trigs (which sometimes go up to 350-400 w/my metabolic
    syndrome)?

    -Preston

  5. Preston,

    Your diabetes dramatically increases your chd risk. A low ldl is good
    prevention. You might look into niaspan (increase HDL).

    [email hidden] (Preston Rich) wrote in message news:<[email hidden]>...

    Quoted message said:

    Sorry. Meant to say "...controlled w/1000 mg. _Metformin_ bid."

    [email hidden] (Preston Rich) wrote in message news:<[email hidden]>...

    Quoted message said:

    I am a 62 yr. old T2 diabetic controlled w/1000 mg. lipitor bid. I'm
    also on a beta blocker w/HCTZ and atorvastatin (Lipitor 10 mg). My
    latest serum tests came in at:

    TC 126
    TG 167
    HDL 50
    LDL 42
    vLDL 33

    What are the consequences of such a low TC and LDL? Should I consider
    coming off the statin and go on a fibrate like gemfibrozil to better
    target my trigs (which sometimes go up to 350-400 w/my metabolic
    syndrome)?

    -Preston

  6. Interestingly enough, in the span between this test above and my
    immediately prior one, the only change I made was to drink 1 lite beer
    daily w/dinner. My HDL went from 42 to 50.

    -Preston

    [email hidden] (Brad Sheppard) wrote in message news:<[email hidden]>...

    Quoted message said:

    Preston,

    Your diabetes dramatically increases your chd risk. A low ldl is good
    prevention. You might look into niaspan (increase HDL).

    [email hidden] (Preston Rich) wrote in message news:<[email hidden]>...

    Quoted message said:

    Sorry. Meant to say "...controlled w/1000 mg. _Metformin_ bid."

    [email hidden] (Preston Rich) wrote in message news:<[email hidden]>...

    Quoted message said:

    I am a 62 yr. old T2 diabetic controlled w/1000 mg. lipitor bid. I'm
    also on a beta blocker w/HCTZ and atorvastatin (Lipitor 10 mg). My
    latest serum tests came in at:

    TC 126
    TG 167
    HDL 50
    LDL 42
    vLDL 33

    What are the consequences of such a low TC and LDL? Should I consider
    coming off the statin and go on a fibrate like gemfibrozil to better
    target my trigs (which sometimes go up to 350-400 w/my metabolic
    syndrome)?

    -Preston

  7. Preston Rich said:

    I am a 62 yr. old T2 diabetic controlled w/1000 mg. lipitor bid. I'm
    also on a beta blocker w/HCTZ and atorvastatin (Lipitor 10 mg). My
    latest serum tests came in at:

    TC 126
    TG 167
    HDL 50
    LDL 42
    vLDL 33

    What are the consequences of such a low TC and LDL?

    Absolutely crazy, what you are doing. Your TC is tooo low. The consequence
    of a low TC is a reduced activity profile. Cholesterol is required for the
    building of sexual hormones, bone metabolism, aldosterone, bile acids, vitD,
    cells...
    You have to reduce your medication.

    Werner

  8. Preston,

    Re: HDL went from 42 to 50 - very good. I got mine to go from 35 to
    69 - moderate drinking, eating oily fish every day,over 1

    hour aerobic exercise daily, and eating moderate amounts of "good"
    fats (olive oil, nuts). Two key numbers for diabetics -

    Hba1c and blood pressure. How do you rate on those? Did you see the
    AHA article on fish oil capsules and/or oily fish - to

    combat high trig you may consume up to 9 capsules a day?
    http://circ.ahajournals.org/cgi/content/full/106/21/2747

    [email hidden] (Preston Rich) wrote in message news:<[email hidden]>...

    Quoted message said:

    Interestingly enough, in the span between this test above and my
    immediately prior one, the only change I made was to drink 1 lite beer
    daily w/dinner. My HDL went from 42 to 50.

    -Preston

    [email hidden] (Brad Sheppard) wrote in message news:<[email hidden]>...

    Quoted message said:

    Preston,

    Your diabetes dramatically increases your chd risk. A low ldl is good
    prevention. You might look into niaspan (increase HDL).

    [email hidden] (Preston Rich) wrote in message news:<[email hidden]>...

    Quoted message said:

    Sorry. Meant to say "...controlled w/1000 mg. _Metformin_ bid."

    [email hidden] (Preston Rich) wrote in message news:<[email hidden]>...
    > I am a 62 yr. old T2 diabetic controlled w/1000 mg. lipitor bid. I'm
    > also on a beta blocker w/HCTZ and atorvastatin (Lipitor 10 mg). My
    > latest serum tests came in at:
    >
    > TC 126
    > TG 167
    > HDL 50
    > LDL 42
    > vLDL 33
    >
    > What are the consequences of such a low TC and LDL? Should I consider
    > coming off the statin and go on a fibrate like gemfibrozil to better
    > target my trigs (which sometimes go up to 350-400 w/my metabolic
    > syndrome)?
    >
    > -Preston

  9. Brad--

    Sorry for the delayed response. My HbA1c is 5.5 and BP is 100/60.
    Boy, that's a LOT of fish oil ;-) I'll smell like a dead grouper ;-)

    -Preston

    [email hidden] (Brad Sheppard) wrote in message news:<[email hidden]>...

    Quoted message said:

    Preston,

    Re: HDL went from 42 to 50 - very good. I got mine to go from 35 to
    69 - moderate drinking, eating oily fish every day,over 1

    hour aerobic exercise daily, and eating moderate amounts of "good"
    fats (olive oil, nuts). Two key numbers for diabetics -

    Hba1c and blood pressure. How do you rate on those? Did you see the
    AHA article on fish oil capsules and/or oily fish - to

    combat high trig you may consume up to 9 capsules a day?
    http://circ.ahajournals.org/cgi/content/full/106/21/2747

    [email hidden] (Preston Rich) wrote in message news:<[email hidden]>...

    Quoted message said:

    Interestingly enough, in the span between this test above and my
    immediately prior one, the only change I made was to drink 1 lite beer
    daily w/dinner. My HDL went from 42 to 50.

    -Preston

    [email hidden] (Brad Sheppard) wrote in message news:<[email hidden]>...

    Quoted message said:

    Preston,

    Your diabetes dramatically increases your chd risk. A low ldl is good
    prevention. You might look into niaspan (increase HDL).

    [email hidden] (Preston Rich) wrote in message news:<[email hidden]>...
    > Sorry. Meant to say "...controlled w/1000 mg. _Metformin_ bid."
    >
    >
    >
    >
    > [email hidden] (Preston Rich) wrote in message news:<[email hidden]>...
    > > I am a 62 yr. old T2 diabetic controlled w/1000 mg. lipitor bid. I'm
    > > also on a beta blocker w/HCTZ and atorvastatin (Lipitor 10 mg). My
    > > latest serum tests came in at:
    > >
    > > TC 126
    > > TG 167
    > > HDL 50
    > > LDL 42
    > > vLDL 33
    > >
    > > What are the consequences of such a low TC and LDL? Should I consider
    > > coming off the statin and go on a fibrate like gemfibrozil to better
    > > target my trigs (which sometimes go up to 350-400 w/my metabolic
    > > syndrome)?
    > >
    > > -Preston

  10. Quoted message said:
    Quoted message said:
    Quoted message said:

    > > I am a 62 yr. old T2 diabetic controlled w/1000 mg. lipitor bid.


    I'm

    Quoted message said:
    Quoted message said:

    > > also on a beta blocker w/HCTZ and atorvastatin (Lipitor 10 mg).


    My

    Quoted message said:
    Quoted message said:

    > > latest serum tests came in at:
    > > > > > > TC 126
    > > TG 167
    > > HDL 50
    > > LDL 42
    > > vLDL 33
    > > > > > > What are the consequences of such a low TC and LDL?


    Should I consider

    Quoted message said:
    Quoted message said:

    > > coming off the statin and go on a fibrate like gemfibrozil to


    better

    Quoted message said:
    Quoted message said:

    > > target my trigs (which sometimes go up to 350-400 w/my metabolic
    > > syndrome)?
    > > > > > > -Preston

    this profile is at goal.

    you might consider hs.CRP and homocystiene levels.

    if you are concerned about too much fish oil, then consider a mercury
    level, as it can be a contaminant and some studies suggest it to be a risk
    factor for promoting atherosclerosis.

    --
    ~~~
    Patrick Blanchard, M.D., A.B.F.P.
    Board Certified in Family Practice

  11. Thu, 30 Oct 2003 11:21:21 -0600 in article
    <[email hidden]> "Patrick Blanchard, M.D."

    Quoted message said:


    if you are concerned about too much fish oil, then consider a mercury
    level, as it can be a contaminant and some studies suggest it to be a risk
    factor for promoting atherosclerosis.


    I'm under impression that the best quality _concentrated_ fish oil products
    don't contain measurable amounts of mercury or other pollutants, because
    these have been removed in the molecular distillation process.

    --
    Matti Narkia

  12. x-no-archive: yes

    Quoted message said:

    if you are concerned about too much fish oil, then consider a mercury
    level, as it can be a contaminant and some studies suggest it to be a risk
    factor for promoting atherosclerosis.

    Buying fish oil labeled "cholesterol free" or "molecularly distilled" is a good
    way to avoid contaminants.

    Susan

  13. Thu, 30 Oct 2003 17:30:03 GMT in article
    <[email hidden]> Matti Narkia

    Quoted message said:

    Thu, 30 Oct 2003 11:21:21 -0600 in article
    <[email hidden]> "Patrick Blanchard, M.D."

    Quoted message said:


    if you are concerned about too much fish oil, then consider a mercury
    level, as it can be a contaminant and some studies suggest it to be a risk
    factor for promoting atherosclerosis.


    I'm under impression that the best quality _concentrated_ fish oil products
    don't contain measurable amounts of mercury or other pollutants, because
    these have been removed in the molecular distillation process.

    See

    Impurities in Fish Oil
    http://www.iherb.com/mercury.html

    "... Molecular distillation is the only method (currently) that can
    remove metals, pcbs and other toxins to below detectable levels for
    human consumption. ..."

    http://www.iherb.com/dha.html

    "Purified by Molecular Distillation-"

    Fish Oil Comparison
    http://www.dr-sears-fishoil.com/compare.asp

    "True molecular distillation process removes all man made pollutants
    such as PCB's, dioxins and mercury."

    --
    Matti Narkia

  14. Matti Narkia said:

    Thu, 30 Oct 2003 11:21:21 -0600 in article
    <[email hidden]> "Patrick Blanchard, M.D."

    Quoted message said:


    if you are concerned about too much fish oil, then consider a mercury
    level, as it can be a contaminant and some studies suggest it to be a
    risk factor for promoting atherosclerosis.


    I'm under impression that the best quality _concentrated_ fish oil
    products
    don't contain measurable amounts of mercury or other pollutants, because
    these have been removed in the molecular distillation process.

    measurable amounts is your key word. this does not mean 'zero'.

    --
    ~~~
    Patrick Blanchard, M.D., A.B.F.P.
    Board Certified in Family Practice

  15. Susan said:

    x-no-archive: yes

    Quoted message said:

    if you are concerned about too much fish oil, then consider a mercury
    level, as it can be a contaminant and some studies suggest it to be a
    risk factor for promoting atherosclerosis.

    Buying fish oil labeled "cholesterol free" or "molecularly distilled" is
    a good
    way to avoid contaminants.

    Susan

    but not a guarantee.

    --
    ~~~
    Patrick Blanchard, M.D., A.B.F.P.
    Board Certified in Family Practice

  16. "Patrick Blanchard, M.D." <[email hidden]> wrote in part:

    Quoted message said:

    if you are concerned about too much fish oil, then consider a mercury
    level, as it can be a contaminant and some studies suggest it to be a risk
    factor for promoting atherosclerosis.

    I've never seen a report of mercury contamination in fish oil. Mercury should
    remain in the muscle tissue and should not be soluble in oil.
    --
    Jim Chinnis Warrenton, Virginia, USA

  17. Matti Narkia <[email hidden]> wrote in part:

    Quoted message said:

    "Purified by Molecular Distillation-"

    What the heck is that? Just an advertising slogan?
    --
    Jim Chinnis Warrenton, Virginia, USA

  18. (Susan ) said:

    Buying fish oil labeled "cholesterol free" or "molecularly distilled" is a good
    way to avoid contaminants.

    Or lied to.

    http://antwrp.gsfc.nasa.gov/apod/ap030724.html
    Lift well, Eat less, Walk fast, Live long.

  19. Jim Chinnis said:
    Quoted message said:

    "Purified by Molecular Distillation-"

    What the heck is that? Just an advertising slogan?

    Some fish oil products are not regulated. they can and do say whatever
    they please. Truth is not a prerequisite.

    http://antwrp.gsfc.nasa.gov/apod/ap030724.html
    Lift well, Eat less, Walk fast, Live long.

  20. Thu, 30 Oct 2003 17:47:50 GMT in article
    <[email hidden]> Jim Chinnis

    Quoted message said:

    Matti Narkia <[email hidden]> wrote in part:

    Quoted message said:

    "Purified by Molecular Distillation-"

    What the heck is that? Just an advertising slogan?

    Found with Google:

    http://www.onelook.com/?w=molecular+distillation

    http://www.infoplease.com/ipd/A0541577.html

    "a vacuum distillation in which the molecules of the distillate reach
    the condenser before colliding with one another."

    http://www.books.md/M/dic/moleculardistillation.php

    http://plastics.about.com/library/glossary/m/bldef-m3492.htm

    "Definition: A process for the separation of polymers into fractions
    of different molecular weight at the lowest possible temperature to
    avoid damage."

    http://www.theglassplant.com/asahi/english/products/vacuum/

    http://www.popeinc.com/pope/wiped_film.htm

    http://www.chelationtherapyonline.com/GarryGordon/KarlLorenResearch/p20.html

    "Molecular distillation is the only method (currently) that can
    remove metals, pcbs and other toxins to below detectable levels for
    human consumption. Most processing keeps the oils at up to 250
    degrees C for up to 6 hours under vacuum. We use a molecular
    distillation process that takes only 45 seconds at 250 degrees C
    under high vacuum. This shortening of the "sit" or "residence" time
    for the process greatly improves the quality because it guarantees
    that no trans fats are created. Other molecular distillation
    processes and steam distillation have the potential to create trans
    fats because of the length of time the oil sits at high temperature.

    Molecular distillation is also used to concentrate and increase the
    levels of EPA and DHA well above the standard 18% EPA and 12% DHA.
    Molecular distillation must occur before concentration begins! If
    the fish oil is concentrated prior to distillation it will also
    concentrate the PCBS's, metals and other toxins significantly
    increasing their levels. Therefore it is essential that fish oil be
    molecularly distilled prior to concentration.

    Please note: The fish oils processed with this technology have very
    low levels of impurities between, below 0.005ppm are very safe for
    human consumption and are below California's Proposition 65
    requirements. It is virtually impossible to remove 100% of all
    impurities but we can get them to below detectable levels.

    Very low levels of PCB's and Heavy metals, PV (peroxide value) and
    Anisidines are the indicators that tell about the purity and quality
    of fish oils. High quality oils will have PV's from 1-3.5meq/kg and
    Anisidines of 13.5meq/kg or lower. Anisidines are just one aspect of
    the oxidative indications and are not as significant as PV.
    Anisidines of between 18 or below are also acceptable."

    --
    Matti Narkia

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