From: "Robert Cohen" <notmilk@e...>
Date: Wed Mar 16, 2005 12:57 pm
Subject: Transfer Factor, Colostrum, and Lactoferrin
ADVERTISEMENT
Transfer Factor, Colostrum, and Lactoferrin
Most snake oils do little more than allow scam artists
to become wealthy at the expense of your health. However,
one poison making the rounds on the Internet is enough to
want to make me stand up and applaud FDA's efforts to
control alternative health therapies and supplements.
Lactoferrins and immunoglobulins are passed on to
mammalian infants from their mother's breast milk.
It is appropriate during an infant's enormous growth
stage to receive these substances, but those same
chemical messengers shoud not reach the unthinking
brain of an adult.
Remarkably, some adults are conned into ingesting
lactoferrins from other species. In this world of Mad
Cow Disease and other bovine diseases, the marketing
behind Colostrum, Transfer Factors, and Lactoferrins
allows normally rational people to subordinate and
transfer innate reason to idiocy. More Re: Colostrum:
http://notmilk.com/deb/053099.html
Thanks to Ian Goddard iamgoddard@y...
for the following references:
___________________________________________________
Brain Res 1994: "The iron-binding protein
lactotransferrin is present in pathologic lesions in a
variety of neurodegenerative disorders [...] An
excessive accumulation of lactotransferrin, as well as
transported iron and aluminum, may lead to a cytotoxic
effect resulting in the formation of intracellular
lesions and neuronal death."
http://calorierestriction.org/pmid/?n=7953673
Acta Neuropathol 1996: "These results suggest that
lactotransferrin may participate actively in the
mechanism of neuronal degeneration in Parkinson's
disease."
http://calorierestriction.org/pmid/?n=8781654
Proc Natl Acad Sci U S A. 1995: "These data suggest
that lactoferrin receptors on vulnerable neurons may
increase intraneuronal iron levels and contribute to
the degeneration of nigral dopaminergic neurons in
Parkinson disease."
http://calorierestriction.org/pmid/?n=7568181
Brain Res Brain Res Rev 1998: "New findings on the
role of LfR (lactotransferrin receptor) [...] in brain
iron transport, obtained during the past 3 years, are
important advances in the fields of physiology and
pathophysiology of brain iron metabolism. According to
these findings, disruption in the expression of these
proteins in the brain is probably one of the important
causes of the altered brain iron metabolism in
age-related neurodegenerative diseases, including
Parkinson's Disease, Alzheimer's disease, Huntington's
disease and amyotrophic lateral sclerosis."
http://calorierestriction.org/pmid/?n=9729418
Brain Research 1994: "The iron-binding protein
lactotransferrin is present in pathologic lesions in a
variety of neurodegenerative disorders [...] An
excessive accumulation of lactotransferrin, as well as
transported iron and aluminum, may lead to a cytotoxic
effect resulting in the formation of intracellular
lesions and neuronal death."
http://calorierestriction.org/pmid/?n=7953673
Biochemistry 2003: "Lactoferrin has previously been
identified in amyloid deposits in the cornea, seminal
vesicles, and brain. We report in this paper a highly
amyloidogenic region of lactoferrin (sequence of
NAGDVAFV) [...] forms amyloid fibrils at pH 7.4 when
incubated at 37 degrees C. [...] We suggest that such
a process could be generally important in the
formation of amyloid fibrils in vivo since the
identification of both full-length protein and protein
fragments is common in ex vivo amyloid deposits."
http://calorierestriction.org/pmid/?n=12525164
Robert Cohen
http://www.notmilk.com