Well, I think the arguments made above are full of holes, so I will point out a few.
Lance has one of the biggest aerobic engines around, always has. Read his book. He was tested at the Cooper Aerobics Center (the folks who invented the words aerobics BTW) as a teenager, perhaps 15, 16 17 years old and his VO2Max stands as the highest ever done there.
When Lance, later after winning a bunch of Tours, says he is not that gifted or unusual, it is not true and he says that for a reason! He wants people to know how hard he has worked post cancer to get the results. He makes no bones about what a lazy, slacker he was before cancer. Check out some videos in 1994 and 1995 and see his beer gut in some of the classics! He also says stuff like that to sell the image and to screw with competitors heads. Check this link re his LT and power:
http://www.jt10000.com/team/events/carmichael99/1.htm
Now, you dont win Tours just with a big VO2MAx, but it is a prerequisite.
As for the argument about 6 minutes and Indurain. Someone please check out how many 22-23 year olds were in the Tour this year and how they did against Lance. Someone please check out where Basso, Vino, Ullrich were in the Tours when they were 23. Ullrich was winning the U23 world road race, the same year Lance won the Worlds in Oslo against Big Mig.
SO yes, the weight loss, the improved pedalling technique and cadence, (check the videos of his cadence and sloppy pedalling while winning the Tour Dupont vs 1999 Tour), the specific and consistent training, doing more training than the competitors, and more desire DO all add up to the difference.
Lance, as is commonly known, trains harder than a lot of racers can race. Ask Roberto,Tyler, and Chechu. Coming out of a mountain training week in early June before the Tour in 2001, they came out with tendinitis in knees due to repetetive punishing climbing intervals in the cold--thats why they were wrapped in guaze and bandages!!
So you either believe the guy or you dont. As for being there and seeing him come in 19 minutes down on Pantani on the Alpe, thats really pretty good for a classics rider, especially since Pantani's hematocrit was probaly higher than his VO2Max in the days before the 50% rule. Where did the classics riders guys come in on Plateau de Beille this year if they were in the race at all--lets see--Weseman, Backstedt, Hammond, Rebellin? I saw where they came in on Luz Ardiden in 2004, 30-40 minutes later!!
No, Lance is clean and folks just cant stand it. Too bad, he will never ride a Tour again.
Peace