Ah, the irony. Lance's Subaru commercial tells us it's in the DNA. But = will Lance say thank you to the "DNA donor" who is his biological = father?
Brian--accept no substitutes--Lafferty Dear, you cannot drink gin and tonic in the middle of the night.=20 You must have whisky to give you energy. --Margaret Thatcher ------=_NextPart_000_0008_01C31B9A.051854A0 Content-Type: text/html; charset="Windows-1252" Content-Transfer-Encoding: quoted-printable
<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN"> <HTML><HEAD> <META http-equiv=3DContent-Type content=3D"text/html; = charset=3Dwindows-1252"> <META content=3D"MSHTML 6.00.2800.1170" name=3DGENERATOR> <STYLE></STYLE> </HEAD> <BODY> <DIV><FONT face=3D"Comic Sans MS" size=3D2>Ah, the irony. Lance's = Subaru=20 commercial tells us it's in the DNA. But will Lance say thank = you to=20 the "DNA donor" who is his biological father?</FONT></DIV> <DV><FONT face=3D"Comic Sans MS" size=3D2></FONT> </DIV> <DVI><FONT face=3D"Comic Sans MS" size=3D2>Brian--accept no=20 substitutes--Lafferty</FONT></DIV> <DVII><FONT size=3D2>Dear, you cannot drink gin and tonic in the middle = of the=20 night. <BR>You must have whisky to give you energy.<BR>--Margaret=20 Thatcher</FONT></DIV></BODY></HTML>
"B. Lafferty" <[email hidden]> wrote in message news:<[email hidden]>...
Quoted message said:
Ah, the irony. Lance's Subaru commercial tells us it's in the DNA. But will Lance say thank you to the "DNA donor" who is his biological father?
He said "thank you" to the guy who gave him his Subaru paycheck though.
Andy
Quoted message said:
Brian--accept no substitutes--Lafferty Dear, you cannot drink gin and tonic in the middle of the night. You must have whisky to give you energy. --Margaret Thatcher --
"Kyle Legate" <[email hidden]> wrote in message "]news:[email hidden]...
Quoted message said:
Andy Coggan said:
"B. Lafferty" <[email hidden]> wrote in message "]news:[email hidden]...
Quoted message said:
Ah, the irony. Lance's Subaru commercial tells us it's in the DNA. But
will Lance say thank you to the "DNA donor" who is his biological father?
Maybe he doesn't really need to - he got all of his mitochondrial DNA from his mother.
Most mitochondrial proteins are encoded by nuclear DNA.
True. But w/o the mitochondrial contribution, you can't make properly functioning mitochondria...hence (apparently) the presence of "ragged red fibers" in certain neuromuscular diseases, in the elderly, in peripheral vascular disease, etc.
"Kyle Legate" <[email hidden]> wrote in message "]news:[email hidden]...
Quoted message said:
Quoted message said:
Most mitochondrial proteins are encoded by nuclear DNA.
True. But w/o the mitochondrial contribution, you can't make properly functioning mitochondria...hence (apparently) the presence of "ragged red fibers" in certain neuromuscular diseases, in the elderly, in peripheral vascular disease, etc.
Of course both genetic contributions are crucial for properly functioning mitochondria, but without the nuclear component mice don't even make it to birth.
eg,
Chen et al, Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol. 2003 Jan 20;160(2):189-200.
Di Pietro et al, Mitochondrial NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is essential for embryonic development. Mol Cell Biol. 2002 Jun;22(12):4158-66.
