"Mike Chippendale" <[email hidden]> wrote in message
news:[email hidden]...
Quoted message said:"Robert" <[email hidden]> wrote in message
Quoted message said:Let me guess here, I bet it was some cult diagnosis of yeast or
something
Quoted message said:Quoted message said:similar.
Not exactly sure what post you actually read Robert, but there was no
cult diagnosis of anything, nor was there anything to indicate that.
The diagnosis was hereditary sphero-cytosis.
"Not anything to indicate the diagnosis HS".
Guidelines for the diagnosis and management of hereditary spherocytosis.
Bolton-Maggs PH, Stevens RF, Dodd NJ, Lamont G, Tittensor P, King MJ;
General Haematology Task Force of the British Committee for Standards in
Haematology.
Manchester Royal Infirmary, Manchester, UK.
Hereditary spherocytosis (HS) is a heterogeneous group of disorders with
regard to clinical severity, protein defects and mode of inheritance. It is
relatively common in Caucasian populations; most affected individuals have
mild or only moderate haemolysis. There is usually a family history, and a
typical clinical and laboratory picture so that the diagnosis is often
easily made without additional laboratory tests. Atypical cases may require
measurement of erythrocyte membrane proteins to clarify the nature of the
membrane disorder and in the absence of a family history, occasionally
molecular genetic analysis will help to determine whether inheritance is
recessive or non-dominant. It is particularly important to rule out
stomatocytosis where splenectomy is contraindicated because of the
thrombotic risk. Mild HS can be managed without folate supplements and does
not require splenectomy. Moderately and severely affected individuals are
likely to benefit from splenectomy, which should be performed after the age
of 6 years and with appropriate counselling about the infection risk. In all
cases careful dialogue between doctor, patient and the family is essential.
Laparoscopic surgery, when performed by experienced surgeons, can result in
a shorter hospital stay and less pain
PMID: 15287938 [PubMed - indexed for MEDLINE]
Quoted message said:
Quoted message said:I noticed that tendency from your original post which is why I did not
reply
Quoted message said:Quoted message said:originially. You self diagnosed yourself without a REAL doctor so you
don't
Quoted message said:Quoted message said:have a REAL diagnosis. There isn't any test in the world that is 100%
specific for anything.
Once again, not sure what the hell you read, my confused friend - but
there was no self-diagnosis of anything. My references to REAL
doctors, were that they couldn't diagnose the disease without my
forceful insistance to perform a certain test (osmotic fragility
[sp?]). Which allowed the diagnosis.
Osmotic fragility is not specific for HS moron. It is not even mentioned
above. Osmotic fragility is is found in many conditions and provides no
specificity. Intrinsic defects in red cell membranes and extrinsic
alterations can make red cells more fragile. Let me repeat your own post.
"I took that information, and had a very specific test done - without my
REAL doctors assistance because he felt it was not even possible for me to
have this disorder - and paid
for it out of my own pocket because my REAL insurance company wouldn't pay
for it without a referral from a REAL doctor - and I helped to solve my own
problem."
HS is a common disorder and not rare as you stated. Atypical cases
presenting de novo and not familial in origin needs special membrane protein
studies dork otherwise you will be surprised down the road with your so
called specific osmotic fragility test.
Family history is important for many, many disorders and the first people
you should be asking is family members. If you have HS then the first people
you should be telling is other members of your extended family.
Spherocytes on blood smear with an increased MCHC on the CBC report is a no
brainer and is the first laboratory indicator pointing towards HS.
My point is be careful what you wish for, talking your way into a diagnosis,
that can be wrong and bite you in the butt.
They do a splenectomy to treat the HS and you come down with an infection
and you die when it turns out you had stomatocytosis instead in where the
splenectomy is not indicated.
I would be [censored] if all they did was an osmotic fragility in a person with
a non family history.
