Vitamin C in plasma

For all you debunkers out there -
It is possible that mega dosing _does_ increase average blood plasma.
Anth

"Anth" <[email hidden]> wrote in message
news:[email hidden]...

Quoted message said:

For all you debunkers out there -
It is possible that mega dosing _does_ increase average blood plasma.
Anth

What is a debunker? Are you referring to those who want truth in health
matters, require rather more stringent evidence than AM supporters, and
know a bit about evaluating it?

This suggests that minor (actually trivial) increases in plasma levels of
vitamin C may be achievable from larger doses if spread out over a day.
This is possible. But studies also show that the cells e.g. white cells-
most immediately exposed to plasma levels- are saturated with vitamin C at
much lower levels.

One review of Vitamin C pharmacology says ---
"Ascorbic acid begins to appear in urine at doses above 100 mg/day,
corresponding to a plasma concentration of about 60 µmol/L, at which point
plasma is 70% saturated and circulating white blood cells are fully
saturated."

It is not likely anyway that such minor changes in blood levels will have
any sigificance for health or disease.

Why bother? No study has ever shown useful effects for megadose vitamins.
Those epidemiological studies showing (possibly non-causal) associations of
benefits from vitamin intake refer to relatively modest intakes compared to
Pauling's recommendations. He naively believed that you could take Vitamin
C up to 20-30 G per day and so long as you were not getting diarrhoea it was
all being utilised. We now know that anything over 500 mgm is either left
in the bowel or goes out in urine. That is not likely to be healthy.

Peter Moran

Quoted message said:

For all you debunkers out there -
It is possible that mega dosing _does_ increase average blood plasma.
Anth

Yes, and its quite possible that Jan lied about ever having her amalgams
removed due to the major inconsistencies in her story.

Quoted message said:

Subject: Re: Vitamin C in plasma
From: "Peter Moran" [email hidden]
Date: 10/3/2003 12:22 PM Pacific Standard Time
Message-id: <[email hidden]>

"Anth" <[email hidden]> wrote in message
news:[email hidden]...

Quoted message said:

For all you debunkers out there -
It is possible that mega dosing _does_ increase average blood plasma.
Anth

What is a debunker?

LOL!!! Quick get a mirror.

Quoted message said:

Are you referring to those who want truth in health matters,

That's strange, they are the ones who tell all the lies here, and no other
debunkers gives a damn.

<snip>

Quoted message said:

Why bother?

Righto, those same debunkers wouldn't want a study that was NOT endorsed by
organized medicine.

Bring on the DRUGS and down with those nasty killer vitamins.

Jan

"Peter Moran" <[email hidden]> wrote in message
news:[email hidden]...

If you look at the curve, it peaks at 3 hours then starts to fall off.
This is probably due to the fact that no more C is being absorbed from the
bowel.
You could keep that falloff period from happening with sustained doses, or
an IV drip.
Also during periods of stress, what's to say that this falloff is more
steeper?
When someone drinks more fluids, does it fall off steeper?
Also what 'kind' of vitamin C are we talking here?
There's many kinds of vitamin C, each with different solubility's.
The questions are endless.

Quoted message said:

Why bother? No study has ever shown useful effects for megadose vitamins.
Those epidemiological studies showing (possibly non-causal) associations

of

Quoted message said:

benefits from vitamin intake refer to relatively modest intakes compared

to

Quoted message said:

Pauling's recommendations. He naively believed that you could take

Vitamin

Quoted message said:

C up to 20-30 G per day and so long as you were not getting diarrhoea it

was

Quoted message said:

all being utilised. We now know that anything over 500 mgm is either

left

Quoted message said:

in the bowel or goes out in urine. That is not likely to be healthy.

Again what type of vitamin C L D molecules ?
Were the experiments flawed?
Regards,
Anth

Vitamin C was Pauling's life work - his pleasure. There's reason enough for
taking mega doses.
He was also suffering from cancer, which he believed could be slowed down by
vitamin c.
Anth

"Peter Moran" <[email hidden]> wrote in message
news:[email hidden]...

Quoted message said:

"Anth" <[email hidden]> wrote in message
news:[email hidden]...

Quoted message said:

For all you debunkers out there -
It is possible that mega dosing _does_ increase average blood plasma.
Anth

What is a debunker? Are you referring to those who want truth in health
matters, require rather more stringent evidence than AM supporters, and
know a bit about evaluating it?

This suggests that minor (actually trivial) increases in plasma levels of
vitamin C may be achievable from larger doses if spread out over a day.
This is possible. But studies also show that the cells e.g. white cells-
most immediately exposed to plasma levels- are saturated with vitamin C at
much lower levels.

One review of Vitamin C pharmacology says ---
"Ascorbic acid begins to appear in urine at doses above 100 mg/day,
corresponding to a plasma concentration of about 60 µmol/L, at which point
plasma is 70% saturated and circulating white blood cells are fully
saturated."

It is not likely anyway that such minor changes in blood levels will have
any sigificance for health or disease.

Why bother? No study has ever shown useful effects for megadose vitamins.
Those epidemiological studies showing (possibly non-causal) associations

of

Quoted message said:

benefits from vitamin intake refer to relatively modest intakes compared

to

Quoted message said:

Pauling's recommendations. He naively believed that you could take

Vitamin

Quoted message said:

C up to 20-30 G per day and so long as you were not getting diarrhoea it

was

Quoted message said:

all being utilised. We now know that anything over 500 mgm is either

left

Quoted message said:

in the bowel or goes out in urine. That is not likely to be healthy.

Peter Moran

Quoted message said:

Vitamin C was Pauling's life work - his pleasure. There's reason enough for
taking mega doses.

Your admiration for Pauling's least impressive professional pursuit and
ignorance of his bona-fide work is astounding. Pauling destroyed some of his
research because it didn't support his fanciful beliefs.

Quoted message said:

He was also suffering from cancer, which he believed could be slowed down by
vitamin c.
Anth

Like yourself, his belief was misplaced.

Quoted message said:

"Peter Moran" <[email hidden]> wrote in message
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