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Turmeric May Protect Against Leukemia -Scientist

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General fitness, health and nutrition
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9 September 2004
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10 September 2004
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Roman Bystrianyk
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  1. http://www.healthsentinel.com/news.php?event=news_print_list_item&id=218

    "Turmeric May Protect Against Leukemia -Scientist", Reuters, September
    9, 2004,
    Link: http://olympics.reuters.com/newsArticle.jhtml?type=healthNews&storyID=6190483

    Turmeric, a spice used extensively in Asia as a key ingredient of
    curry, may be protecting children against leukemia, a scientist said
    on Thursday.

    Rates of the blood cancer have been rising steadily for the past 50
    years but its incidence in Asia is much lower than in the West.

    Professor Moolky Nagabhushan, of the Loyola University Medical Center
    in Chicago, told a conference that factor could be due, at least
    partly, to turmeric.

    "Some of the known risk factors that contribute to the high incidence
    of childhood leukemia are the interaction of many lifestyle and
    environmental factors," he said.

    Scientists suspect some children are born with a predisposition to the
    illness, which occurs most often in children aged 1-4, but that they
    do not develop the disease unless it is triggered by environmental
    factors.

    Infections, viruses, radiation, pesticides and chemicals are among the
    suspected culprits.

    "Our studies show that turmeric -- and its coloring ... curcumin -- in
    the diet mitigate the effects of some of these risk factors,"
    Nagabhushan added.

    He and his colleagues showed that the spice irreversibly inhibits the
    multiplication of leukemia cells in laboratory studies and seems to
    protect against damage caused by cigarette smoke and eating certain
    processed foods.

    Dr Marilyn Kwan, of the University of California, Berkeley, presented
    separate results of a study of more than 300 children which showed the
    benefits of eating healthy foods.

    "We found that regular consumption of oranges and/or bananas during
    the first two years of life was associated with a reduced risk of
    childhood leukemia," Kwan said.

    "These findings are consistent with the protective role of fruits and
    vegetables observed in adult cancers," she added.

    Oranges are rich in vitamin C and bananas have high levels of
    potassium, both of which are thought to protect against cancer.

    The week-long childhood leukemia conference is organized by the
    British charity Children with Leukemia.

  2. Roman Bystrianyk said:

    Turmeric, a spice used extensively in Asia as a key ingredient of
    curry, may be protecting children against leukemia, a scientist said
    on Thursday.

    May? It "may" make it worse, too. Without evidence,
    you don't know anything.

    Quoted message said:

    Rates of the blood cancer have been rising steadily for the past 50
    years but its incidence in Asia is much lower than in the West.

    Professor Moolky Nagabhushan, of the Loyola University Medical Center
    in Chicago, told a conference that factor could be due, at least
    partly, to turmeric.

    Or it could be soy. Or it could be greater fish consumption.
    Or it could be lesser consumption of red meat. Or it could
    be more consumption of rice vs. wheat and corn. Without
    evidence, anything is possible.

    Quoted message said:

    "Some of the known risk factors that contribute to the high incidence
    of childhood leukemia are the interaction of many lifestyle and
    environmental factors," he said.

    Many. Note that word "many".

    Quoted message said:

    Scientists suspect some children are born with a predisposition to the
    illness, which occurs most often in children aged 1-4, but that they
    do not develop the disease unless it is triggered by environmental
    factors.

    Suspect. Note that word "suspect".

    Quoted message said:

    Infections, viruses, radiation, pesticides and chemicals are among the
    suspected culprits.

    Suspected. In the absence of evidence, everything
    is a suspect.

    Quoted message said:

    "Our studies show that turmeric -- and its coloring ... curcumin -- in
    the diet mitigate the effects of some of these risk factors,"
    Nagabhushan added.

    Some? Mitigate a "suspected" risk factor?
    That "may" cause a disease? That's a mighty
    strained chain of reasoning.

    Quoted message said:

    He and his colleagues showed that the spice irreversibly inhibits the
    multiplication of leukemia cells in laboratory studies and seems to
    protect against damage caused by cigarette smoke and eating certain
    processed foods.

    Cells are not organs, and organs are not organisms.
    A lab study is a far cry from a study in animals or
    people. A good lab study with clear results provides
    a basis for looking further by doing studies in animals
    or people.

    Is this a good study with clear results? Even the
    authors are cautios in their wording. Note the word
    "seems". If curcumin protected the cells, they would
    have said "does", but even the people who did the study
    knew that it would be wrong to say that curcumin "does"
    protect.

    Quoted message said:

    Dr Marilyn Kwan, of the University of California, Berkeley, presented
    separate results of a study of more than 300 children which showed the
    benefits of eating healthy foods.

    And what does this have to do with tumeric or curcumin?

    Quoted message said:

    "We found that regular consumption of oranges and/or bananas during
    the first two years of life was associated with a reduced risk of
    childhood leukemia," Kwan said.

    Oranges and bananas are colored similarly to tumeric,
    but they do not contain curcumin.

    Quoted message said:

    "These findings are consistent with the protective role of fruits and
    vegetables observed in adult cancers," she added.

    Tumeric is not a fruit. The part of the tumeric plant
    which is eaten is not the leaves or stems.

    Quoted message said:

    Oranges are rich in vitamin C and bananas have high levels of
    potassium, both of which are thought to protect against cancer.

    No curcumin there.

    Quoted message said:

    The week-long childhood leukemia conference is organized by the
    British charity Children with Leukemia.

    Your posting contained NO useful information.
    Just a bunch of cagey stuff from people working
    (or not working) with tumeric or curcumin.

  3. Great post. Thanks so much Roman.

    I believe that God gave us everything we needed here .

    On Thu, 09 Sep 2004 19:43:04 GMT, Mark Thorson <[email hidden]>

    Quoted message said:

    May? It "may" make it worse, too. Without evidence,
    you don't know anything.

    That's the typical Quack Logic at work again ... just like Utz lying
    that there was "no evidence silicon (his misspellilng) implants ever
    harmed anyone."

    Absurd.

    Close your eyes and be blind to the evidence is the Junk Science/Quack
    Credo.

    I trust in God's creations ... far more than the Pharmaceutical
    Cartels ...

    From: [email hidden] (Roman Bystrianyk)

    http://www.healthsentinel.com/news.php?event=news_print_list_item&id=218

    "Turmeric May Protect Against Leukemia -Scientist", Reuters, September
    9, 2004,
    Link:
    http://olympics.reuters.com/newsArticle.jhtml?type=healthNews&storyID=6190483

    Turmeric, a spice used extensively in Asia as a key ingredient of
    curry, may be protecting children against leukemia, a scientist said
    on Thursday.

    Rates of the blood cancer have been rising steadily for the past 50
    years but its incidence in Asia is much lower than in the West.

    Professor Moolky Nagabhushan, of the Loyola University Medical Center
    in Chicago, told a conference that factor could be due, at least
    partly, to turmeric.

    "Some of the known risk factors that contribute to the high incidence
    of childhood leukemia are the interaction of many lifestyle and
    environmental factors," he said.

    Scientists suspect some children are born with a predisposition to the
    illness, which occurs most often in children aged 1-4, but that they
    do not develop the disease unless it is triggered by environmental
    factors.

    Infections, viruses, radiation, pesticides and chemicals are among the
    suspected culprits.

    "Our studies show that turmeric -- and its coloring ... curcumin -- in
    the diet mitigate the effects of some of these risk factors,"
    Nagabhushan added.

    He and his colleagues showed that the spice irreversibly inhibits the
    multiplication of leukemia cells in laboratory studies and seems to
    protect against damage caused by cigarette smoke and eating certain
    processed foods.

    Dr Marilyn Kwan, of the University of California, Berkeley, presented
    separate results of a study of more than 300 children which showed the
    benefits of eating healthy foods.

    "We found that regular consumption of oranges and/or bananas during
    the first two years of life was associated with a reduced risk of
    childhood leukemia," Kwan said.

    "These findings are consistent with the protective role of fruits and
    vegetables observed in adult cancers," she added.

    Oranges are rich in vitamin C and bananas have high levels of
    potassium, both of which are thought to protect against cancer.

    The week-long childhood leukemia conference is organized by the
    British charity Children with Leukemia.

  4. "Ilena Rose" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:


    Great post. Thanks so much Roman.

    I believe that God gave us everything we needed here .

    Including the chemotherapeutic agents produced by the pharmaceutical
    companies that give a 90% cure rate for childhood acut lymphoblastic
    leukemia.

    Quoted message said:


    On Thu, 09 Sep 2004 19:43:04 GMT, Mark Thorson <[email hidden]>

    Quoted message said:

    May? It "may" make it worse, too. Without evidence,
    you don't know anything.

    That's the typical Quack Logic at work again ... just like Utz lying
    that there was "no evidence silicon (his misspellilng) implants ever
    harmed anyone."

    Absurd.

    Close your eyes and be blind to the evidence is the Junk Science/Quack
    Credo.

    Quacks don't rely on evidence but only on emotion like yours.

    Quoted message said:


    I trust in God's creations ... far more than the Pharmaceutical
    Cartels ...

    The pharmaceutical companies are not God's creations?
    More emotional garbage. You would be the first to cry foul if a sick child
    were to be denied medications and then call the same companies evil.
    You need to grow up and realize that we are all Gods creatures and that evil
    resides in all of us and not just "things" like drugs.

    Quoted message said:


    From: [email hidden] (Roman Bystrianyk)

    http://www.healthsentinel.com/news.php?event=news_print_list_item&id=218

    "Turmeric May Protect Against Leukemia -Scientist", Reuters, September
    9, 2004,
    Link:


    http://olympics.reuters.com/newsArticle.jhtml?type=healthNews&storyID=6190483

    Quoted message said:


    Turmeric, a spice used extensively in Asia as a key ingredient of
    curry, may be protecting children against leukemia, a scientist said
    on Thursday.

    Rates of the blood cancer have been rising steadily for the past 50
    years but its incidence in Asia is much lower than in the West.

    Professor Moolky Nagabhushan, of the Loyola University Medical Center
    in Chicago, told a conference that factor could be due, at least
    partly, to turmeric.

    "Some of the known risk factors that contribute to the high incidence
    of childhood leukemia are the interaction of many lifestyle and
    environmental factors," he said.

    Scientists suspect some children are born with a predisposition to the
    illness, which occurs most often in children aged 1-4, but that they
    do not develop the disease unless it is triggered by environmental
    factors.

    Infections, viruses, radiation, pesticides and chemicals are among the
    suspected culprits.

    "Our studies show that turmeric -- and its coloring ... curcumin -- in
    the diet mitigate the effects of some of these risk factors,"
    Nagabhushan added.

    He and his colleagues showed that the spice irreversibly inhibits the
    multiplication of leukemia cells in laboratory studies and seems to
    protect against damage caused by cigarette smoke and eating certain
    processed foods.

    Dr Marilyn Kwan, of the University of California, Berkeley, presented
    separate results of a study of more than 300 children which showed the
    benefits of eating healthy foods.

    "We found that regular consumption of oranges and/or bananas during
    the first two years of life was associated with a reduced risk of
    childhood leukemia," Kwan said.

    "These findings are consistent with the protective role of fruits and
    vegetables observed in adult cancers," she added.

    Oranges are rich in vitamin C and bananas have high levels of
    potassium, both of which are thought to protect against cancer.

    The week-long childhood leukemia conference is organized by the
    British charity Children with Leukemia.

  5. Quoted message said:


    Quoted message said:

    Turmeric, a spice used extensively in Asia as a key ingredient of
    curry, may be protecting children against leukemia, a scientist said
    on Thursday.

    May? It "may" make it worse, too. Without evidence,
    you don't know anything.

    One study for your consideration. Enjoy your day.

    Inhibitory Effects of Curcumin and Tetrahydrocurcuminoids on the Tumor
    Promotor-induced Reactive Oxygen Species Generation in Leukocytes in
    vitro and in vivo
    Yoshimasa Nakamura; Yoshimi Ohto; Akira Murakami; Toshihko Osawa and
    Hajime Ohigashi, "Inhibitory Effects of Curcumin and
    Tetrahydrocurcuminoids on the Tumor Promotor-induced Reactive Oxygen
    Species Generation in Leukocytes in vitro and in vivo", Japanese
    Journal of Cancer Research, April 1, 1998, Vol. 89, Num. 0, pp.
    361-370
    "The inhibitory effects of curcumin and tetrahydrocurcuminoids on
    tumor promoter-induced oxidative stress in vitro and in vivo were
    investigated. Curcumin, tetrahydrocurcumin (THC) and
    dihydroxytetrahydrocurcumin (DHTHC) exhibited significant inhibitory
    effects on 12-O-tetradecnaoylphorbol-13-acetate (TPA)-induced O2-
    generation in differentiated HL-60 cells. … Thus we concluded that
    curcuminoids significantly suppress TPA-induced oxidative stress via
    both interference with infiltration of leukocytes into the
    inflammatory regions and inhibition of their activation."

    "Curcumin (diferuloylmethane), a major yellow pigment of turmeric
    occurring in the rhizomes of several tropical gingers such as Curcuma
    longa, is commonly used as a coloring condiment. A wide range of
    biological and pharmacological activities of curcumin have thus far
    been investigated. Curcumin is a potent inhibitor of mutagenesis and
    chemically induced carcinogenesis. For example, topical application of
    commercial food grade curcumin containing minor amounts of derivatives
    or pure curcumin strongly inhibited
    7,12-dimethylbenz-[a]anthracene-induced tumor initiation and
    12-O-tetradecanoylphorbol-13-acetate (TPA)-induced tumor promotion in
    mouse skin. Dietary curcumin also inhibited chemical carcinogenesis in
    some target organs of rats and mice. Curcumin appears to have
    practical cancer-preventive potential in view of its relatively low
    toxicity to rodents."

    "The action mechanism(s) of curcumin for anti-tumor promoting activity
    is complicated. Among a wide range of biological and biochemical
    activities, its antioxidative property may be one of the essential
    actions for anti-tumor promotion. Previously, curcuminoids have been
    reported to exhibit antioxidative activities in some in vitro lipid
    peroxidation systems and to suppress TPA-induced hydrogen peroxide
    (H2O2) production and oxidized DNA formation in mouse epidermis.
    Curcumin is also an inhibitor of neutrophil responses and of
    superoxide (O2-) generation in macrophages. Tumor promoter-induced
    reactive oxygen species (ROS) generation has been considered to play
    important roles in tumor promotion."

    "We and others have recently reported that some natural
    chemopreventers O2- inhibit generation by leukocytes, suggesting that
    this inhibition to be at least one of the mechanisms of anti-tumor
    promotion."

    "In conclusion, the curcuminoids significantly suppress TPA-induced
    oxidative stress through both suppression of leukocyte infiltration
    into the inflammatory regions and inhibition of the activation of
    leukocytes, including neutrophils. In particular, curcumin most
    effectively inhibits TPA-induced oxidative stress. Nevertheless, THC
    and DHTHC have some advantages for application as food additives
    because of their colorless character and easy preparation by usual
    hydrogenation of curcumin. Further investigation of these curcuminoids
    may lead to chemopreventive application in humans."

  6. In article <[email hidden]>,

    Ilena Rose said:

    Great post. Thanks so much Roman.

    Quoted message said:

    I believe that God gave us everything we needed here .

    Quoted message said:

    On Thu, 09 Sep 2004 19:43:04 GMT, Mark Thorson <[email hidden]>
    wrote:

    Quoted message said:
    Quoted message said:

    May? It "may" make it worse, too. Without evidence,
    you don't know anything.

    Quoted message said:

    That's the typical Quack Logic at work again ... just like Utz lying
    that there was "no evidence silicon (his misspellilng) implants ever
    harmed anyone."

    There is considerable evidence that curcumin, the
    active ingredient in turmeric which gives it its
    color, is a potent antioxidant and otherwise
    quite useful.

    --
    This address is for information only. I do not claim that these views
    are those of the Statistics Department or of Purdue University.
    Herman Rubin, Department of Statistics, Purdue University
    [email hidden] Phone: (765)494-6054 FAX: (765)494-0558

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