When considering the use of bike trailers for pet transport, what are the key factors to evaluate in terms of trailer design and configuration to ensure optimal safety, comfort, and visibility for both the cyclist and the pet? Specifically, how do the trailers wheelbase, suspension system, and enclosure design impact the overall stability and maneuverability of the setup, particularly when navigating varying terrain and road conditions? Additionally, what are the most effective methods for securing the pet within the trailer, and how can cyclists balance the need for ventilation and visibility with the need for protection from the elements and road debris? Furthermore, are there any specific regulations or standards that cyclists should be aware of when using bike trailers for pet transport, and how can they ensure compliance with local laws and regulations?