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Re: Healthy saturated fat?

Started by Bob in CT · · Last activity · 30 posts · 966 views

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General fitness, health and nutrition
Published
3 August 2004
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28 August 2004
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Bob in CT
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  1. Why is this a bummer?

    Ignoramus7404 said:

    What a bummer!

    ``The present study demonstrated that the addition of SF to the meal
    resulted in lower postprandial glucose and insulin than when the meal
    contained MUFA. Thus, SF may be useful in controlling postprandial
    glucose.''

    http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10774766

    Comparison of the effect of saturated and monounsaturated fat on
    postprandial plasma glucose and insulin concentration in women with
    gestational diabetes mellitus.

    Ilic S, Jovanovic L, Pettitt DJ.

    Sansum Medical Research Institute, Santa Barbara, California 93105,
    USA.

    The goal of this study was to determine whether the type of fat plays
    a role in the glucose response to a meal, independent of the
    carbohydrate content. Ten gestational diabetic women (gestational
    weeks 29-34) who were well controlled on diet alone were randomized as
    to the order in which they would eat a meal, after overnight fast,
    containing saturated fat (SF) or monounsaturated fat (MUFA). Blood was
    drawn at 0, 60, 120, and 180 min for plasma glucose, insulin, lipid
    profile (triglycerides, total cholesterol, HDL-cholesterol,
    LDL-cholesterol, VLDL-cholesterol) and free fatty acids. After 2
    weeks, each patient received the other type of meal. The test meal was
    composed of 20% of the total daily caloric needs based on ideal body
    weight. The area under the curve showed a significantly lower glucose
    concentration for SF meal (p = 0.001). Serum insulin concentrations
    followed the glucose response with the peak at the 60-min time point
    and a significantly lower concentration at the 180-min time point in
    the SF than in the MUFA group. The present study demonstrated that the
    addition of SF to the meal resulted in lower postprandial glucose and
    insulin than when the meal contained MUFA. Thus, SF may be useful in
    controlling postprandial glucose.

    --
    Bob in CT
    Remove ".x" to reply

  2. Bob in CT generously shared with us this little ditty:

    Quoted message said:

    Why is this a bummer?

    I am thinking 'tongue in cheek'. I imagine hearing some such comments
    echo across the landscape of the so-called health-conscious types-- you
    know the ones who eat wheat germ and have heart palpitations at the
    thought of fat in their food and believe a glass of sugar water with a
    smidge of vitimin c in it is good for you.

    As in: oh gee, lookitthis, too bad it will kill you with heart disease
    while it manages your diabetes!

    --
    revek
    I'll deny anything!

  3. revek said:

    Bob in CT generously shared with us this little ditty:

    Quoted message said:

    Why is this a bummer?

    I am thinking 'tongue in cheek'. I imagine hearing some such comments
    echo across the landscape of the so-called health-conscious types-- you
    know the ones who eat wheat germ and have heart palpitations at the
    thought of fat in their food and believe a glass of sugar water with a
    smidge of vitimin c in it is good for you.

    As in: oh gee, lookitthis, too bad it will kill you with heart disease
    while it manages your diabetes!

    Ahhh, I need to up my humor meter, I see.

    --
    Bob in CT
    Remove ".x" to reply

  4. "Bob in CT" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:
    revek said:

    Bob in CT generously shared with us this little ditty:

    Quoted message said:

    Why is this a bummer?

    I am thinking 'tongue in cheek'. I imagine hearing some such comments
    echo across the landscape of the so-called health-conscious types-- you
    know the ones who eat wheat germ and have heart palpitations at the
    thought of fat in their food and believe a glass of sugar water with a
    smidge of vitimin c in it is good for you.

    As in: oh gee, lookitthis, too bad it will kill you with heart disease
    while it manages your diabetes!

    Ahhh, I need to up my humor meter, I see.

    --
    Bob in CT
    Remove ".x" to reply

    Considering that cardio-vascular disease is the major cause of death for
    diabetics, it makes perfect sense to me. I was just assuming that he was
    considering his lipid panel as well as BG control. Although perhaps he was
    being humerous instead? go on Ig, solve the mystery 😉
    --------------------
    VBH
    T2/UK/A1c 5.8/ 1000Met/Dx Oct-03

  5. Ignoramus7404 said:
    In article said:

    "Bob in CT" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    On Tue, 3 Aug 2004 11:18:00 -0500, revek <[email hidden]> wrote:

    > Bob in CT generously shared with us this little ditty:
    >> Why is this a bummer?
    >
    > I am thinking 'tongue in cheek'. I imagine hearing some such
    comments
    > echo across the landscape of the so-called health-conscious types--
    you
    > know the ones who eat wheat germ and have heart palpitations at the
    > thought of fat in their food and believe a glass of sugar water with
    a
    > smidge of vitimin c in it is good for you.
    >
    > As in: oh gee, lookitthis, too bad it will kill you with heart
    disease
    > while it manages your diabetes!
    >
    >

    Ahhh, I need to up my humor meter, I see.

    Considering that cardio-vascular disease is the major cause of death for
    diabetics, it makes perfect sense to me. I was just assuming that he
    was
    considering his lipid panel as well as BG control. Although perhaps he
    was
    being humerous instead? go on Ig, solve the mystery 😉
    VBH
    T2/UK/A1c 5.8/ 1000Met/Dx Oct-03

    I was part humorous, but part surprised.

    I suspect, based on my current readings, that saturated fat is
    maligned unfairly. That was the basis for the humorous attitude, so
    see saturated fat perform pretty well.

    I was surprised that saturated fat worked BETTER THAN OTHER
    FATS. That, to be, is counterintuitive. Why does it work better? I do
    not know.

    i

    Personally, I'm surprised that saturated fat is bad, simply from a
    chemical perspective. Saturated fat means that all possible locations on
    the fat are filled. To me, this should yield a relatively inert
    substance. However, the body isn't always logical.

    --
    Bob in CT
    Remove ".x" to reply

  6. revek said:


    As in: oh gee, lookitthis, too bad it will kill you with heart disease
    while it manages your diabetes!

    Possibly one of those "many a true word spoken in jest" statements. I
    don't get palpitations over sat fat (just finished my bacon and egg
    breakfast - steak for dinner tonight) but I do trim and drain as much as
    possible. It's all a matter of balance; so lipids, BGs, excess weight,
    exercise are all part of the equation.

    Cheers, Alan, T2 d&e, Australia.
    Remove weight and carbs to email.
    --
    Everything in Moderation - Except Laughter.

  7. Alan generously shared with us this little ditty:

    Quoted message said:

    On Tue, 3 Aug 2004 11:18:00 -0500, "revek" <[email hidden]>

    Quoted message said:


    As in: oh gee, lookitthis, too bad it will kill you with heart
    disease while it manages your diabetes!

    Possibly one of those "many a true word spoken in jest" statements. I
    don't get palpitations over sat fat (just finished my bacon and egg
    breakfast - steak for dinner tonight) but I do trim and drain as much
    as possible. It's all a matter of balance; so lipids, BGs, excess
    weight, exercise are all part of the equation.

    Cheers, Alan, T2 d&e, Australia.
    Remove weight and carbs to email.

    Whatever works for you is what you need to go with. However sat fat is
    not the evil so many have made it out to be.

    --
    revek
    ".Sig, .sig a .sog, .sig out loud, .sig out .strog ." -- Karen
    Carpenter with a head cold.

  8. Bob in CT said:


    Quoted message said:

    I suspect, based on my current readings, that saturated fat is
    maligned unfairly. That was the basis for the humorous attitude, so
    see saturated fat perform pretty well.

    I was surprised that saturated fat worked BETTER THAN OTHER
    FATS. That, to be, is counterintuitive. Why does it work better? I do
    not know.

    i

    Personally, I'm surprised that saturated fat is bad, simply from a
    chemical perspective. Saturated fat means that all possible locations
    on the fat are filled. To me, this should yield a relatively inert
    substance. However, the body isn't always logical.

    I am sure that if you look, you will find plenty of uses of the
    saturated fats in basic body cellular structures.

    However, I have no good references.... just some vague recollections
    which could be mistaken...

    Jim

  9. Hi Ig:

    Quoted message said:

    do you have any references to valid current research (randomized
    controlled studies) of saturated animal fat? I looked a lot in medline
    yesterday, and besides the study that I posted to start this thread,
    there was nothing. Dozens of references to saturated fat as bad
    without any substantiation.

    Some key words/phrases: ceramide, beta cell apoptosis
    High-Wire search for phrase "beta cell apoptosis"+saturated+fatty
    resulted in 57 finds - http://tinyurl.com/4tsud.

    Adding ceramide to the above search terms resulted in 34 finds -
    http://tinyurl.com/6oysd

    Palmitate is a type of saturated fatty acid.

    Monounsaturated Fatty Acids Prevent the Deleterious Effects of Palmitate
    and High Glucose on Human Pancreatic ß-Cell Turnover and Function
    http://diabetes.diabetesjournals.org/cgi/content/full/52/3/726
    "Glucotoxicity and lipotoxicity contribute to the impaired ß-cell
    function observed in type 2 diabetes. Here we examine the effect of
    saturated and monounsaturated fatty acids at different glucose
    concentrations on human ß-cell turnover and secretory function. Exposure
    of cultured human islets to saturated fatty acid and/or to an elevated
    glucose concentration for 4 days increased ß-cell DNA fragmentation and
    decreased ß-cell proliferation. In contrast, the monounsaturated
    palmitoleic acid or oleic acid did not affect DNA fragmentation and
    induced ß-cell proliferation. Moreover, each monounsaturated fatty acid
    prevented the deleterious effects of both palmitic acid and high glucose
    concentration. The cell-permeable ceramide analogue C2-ceramide mimicked
    both the palmitic acid-induced ß-cell apoptosis and decrease in
    proliferation. Furthermore, the ceramide synthetase inhibitor fumonisin
    B1 blocked the deleterious effects of palmitic acid on ß-cell turnover.
    In addition, palmitic acid decreased Bcl-2 expression and induced
    release of cytochrome c from the mitochondria into the cytosol, which
    was prevented by fumonisin B1 and by oleic acid. Finally, each
    monounsaturated fatty acid improved ß-cell secretory function that was
    reduced by palmitic acid and by high glucose. Thus, in human islets, the
    saturated palmitic acid and elevated glucose concentration induce ß-cell
    apoptosis, decrease ß-cell proliferation, and impair ß-cell function,
    which can be prevented by monounsaturated fatty acids. The deleterious
    effect of palmitic acid is mediated via formation of ceramide and
    activation of the apoptotic mitochondrial pathway, whereas Bcl-2 may
    contribute to the protective effect of monounsaturated fatty acids."

    Read the whole article and some others in the searches above. Also read
    some of the follow up articles that cite the articles. Free fatty acids
    (FFA) are also significant for type 2 diabetes and can result from
    dyfunctional metabolism of protein, carbohydrates, and fatty acids
    particularly when there is a positive energy balance such as occurs in
    eating to much and not getting enough exercise.

    Frank

  10. jbuch said:


    I am sure that if you look, you will find plenty of uses of the
    saturated fats in basic body cellular structures.

    However, I have no good references.... just some vague recollections
    which could be mistaken...

    This is probably true. The nitty-gritty issue is really one of balance.
    It is like arachidonic acid (AA) derived from omega 6 series fatty
    acids. AA is important in some physiological actions, but it can give
    you a headache or other aches and pains if you have a bad omega 6 to
    omega 3 balance in your diet.

    Frank

  11. Jefferson said:
    jbuch said:


    I am sure that if you look, you will find plenty of uses of the
    saturated fats in basic body cellular structures.

    However, I have no good references.... just some vague recollections
    which could be mistaken...

    This is probably true. The nitty-gritty issue is really one of balance.
    It is like arachidonic acid (AA) derived from omega 6 series fatty
    acids. AA is important in some physiological actions, but it can give
    you a headache or other aches and pains if you have a bad omega 6 to
    omega 3 balance in your diet.

    Frank

    Yes, Balance.

    we really screw ourselves up with the attitude that:

    "If a little is good, a lot must be better."

    Rather than..."Now that I've got that, what else do I need to add to it?"

    These answers, unfortunately, won't work out to be identical for all,
    because we complex bio-machines are built with all kinds of modest
    programming errors.

    Carbohydrate handling problems for some, Fat handling problems for
    others, Cholesterol handling problems for still others, and even more
    problems in case you haven't gotten one of the above.

    Trial and ERROR still seems necessary.

    Jim

    Jim

  12. Alan said:

    Possibly one of those "many a true word spoken in jest" statements. I
    don't get palpitations over sat fat (just finished my bacon and egg
    breakfast - steak for dinner tonight) but I do trim and drain as much as
    possible. It's all a matter of balance; so lipids, BGs, excess weight,
    exercise are all part of the equation.

    I'm getting to be of the opinion that there is no 'right diet' suitable
    for 'everyone' with regard to macronutrients (iow
    fat+protein+carbohydrate). I've always had problems with wheat. After
    diebetes, with all starch. I'm getting to think that some are suited for
    a mainly sat fat/meat diet, others more towards fish/unsaturated fat,
    still others a vegetarian diet, still others a diet high in carbohydrate.

    For me, a diet high in fish/protein/ and vegetables with a low carb
    concentration seems to work best. but I'd be wary of recommending it to
    anyone else for the reasons stated above. Wouldn't it be easy if one
    size fits all. But it seems that for some of us, there isn't even a size.

    --
    John38 : t2 since 11/03

  13. John38 generously shared with us this little ditty:

    Quoted message said:
    Alan said:

    Possibly one of those "many a true word spoken in jest" statements. I
    don't get palpitations over sat fat (just finished my bacon and egg
    breakfast - steak for dinner tonight) but I do trim and drain as
    much as possible. It's all a matter of balance; so lipids, BGs,
    excess weight, exercise are all part of the equation.

    I'm getting to be of the opinion that there is no 'right diet'
    suitable for 'everyone' with regard to macronutrients (iow
    fat+protein+carbohydrate). I've always had problems with wheat. After
    diebetes, with all starch. I'm getting to think that some are suited
    for a mainly sat fat/meat diet, others more towards fish/unsaturated
    fat, still others a vegetarian diet, still others a diet high in
    carbohydrate.

    For me, a diet high in fish/protein/ and vegetables with a low carb
    concentration seems to work best. but I'd be wary of recommending it
    to anyone else for the reasons stated above. Wouldn't it be easy if
    one size fits all. But it seems that for some of us, there isn't even
    a size.

    Wize man. 🙂

    --
    revek
    "Time is an illusion perpetrated by the manufacturers of space."

  14. "John38" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    For me, a diet high in fish/protein/ and vegetables with a low carb
    concentration seems to work best. but I'd be wary of recommending it to
    anyone else for the reasons stated above. Wouldn't it be easy if one
    size fits all. But it seems that for some of us, there isn't even a size.

    Is your blood type O? My mother swears by this blood type diet she is on,
    "Eat Right For Your Type." It sounded kind of weird to me, but then I read
    a science magazine article about them trying to come up with genetic tests
    to predict which drugs will work for different people which seems like a
    similar kind of thing.

  15. In article <[email hidden]>, None Given
    <[email hidden]> writes

    Quoted message said:

    "John38" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    For me, a diet high in fish/protein/ and vegetables with a low carb
    concentration seems to work best. but I'd be wary of recommending it to
    anyone else for the reasons stated above. Wouldn't it be easy if one
    size fits all. But it seems that for some of us, there isn't even a size.

    Is your blood type O? My mother swears by this blood type diet she is on,
    "Eat Right For Your Type." It sounded kind of weird to me, but then I read
    a science magazine article about them trying to come up with genetic tests
    to predict which drugs will work for different people which seems like a
    similar kind of thing.

    you know, I have no idea what my blood type is. I would be interested in
    the science describing the diet<>blood type relationship. Any links?
    --
    John38 : t2 since 11/03 : current Hb1Ac=5.5% :

  16. "John38" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:
    Quoted message said:

    Is your blood type O? My mother swears by this blood type diet she is


    on,

    Quoted message said:
    Quoted message said:

    "Eat Right For Your Type." It sounded kind of weird to me, but then I


    read

    Quoted message said:
    Quoted message said:

    a science magazine article about them trying to come up with genetic


    tests

    Quoted message said:
    Quoted message said:

    to predict which drugs will work for different people which seems like a
    similar kind of thing.


    you know, I have no idea what my blood type is. I would be interested in
    the science describing the diet<>blood type relationship. Any links?

    I don't know if there is any real science to the diet.
    http://www.dadamo.com/ is the URL, the book is this one
    http://www.amazon.com/exec/obidos/tg/detail/-/039914255X/104-1156044-0251119?v=glance
    There are also some sites that say the guy is full of s*&t and it's all a
    racket, look at google for "eat right for your type"

  17. John38 said:

    ou know, I have no idea what my blood type is. I would be interested in
    the science describing the diet<>blood type relationship. Any links?

    None worth spending two seconds over.

  18. MU said:
    John38 said:

    ou know, I have no idea what my blood type is. I would be interested in
    the science describing the diet<>blood type relationship. Any links?

    None worth spending two seconds over.

    While I don't believe in the blood-type diet, I do believe that genetics
    plays a role in what type of diet we should choose. I'd love to see a
    study using genetics, low fat, low carb, and mediterranean.

    --
    Bob in CT
    Remove ".x" to reply

  19. Bob in CT said:

    While I don't believe in the blood-type diet, I do believe that genetics
    plays a role in what type of diet we should choose. I'd love to see a
    study using genetics, low fat, low carb, and mediterranean.

    No genetics involved here.

    http://www.heartmdphd.com/losewtnd.pdf

  20. None Given said:

    Is your blood type O? My mother swears by this blood type diet she is on,
    "Eat Right For Your Type." It sounded kind of weird to me, but then I read
    a science magazine article about them trying to come up with genetic tests
    to predict which drugs will work for different people which seems like a
    similar kind of thing.

    The term ABO is used for blood types. Both A and B types have different
    types of sugar structure in their antigenes, whereas type O does not.
    But then again DNA has a sugar backbone. Sugar here is not the household
    variety.

    "The ABO blood group antigens are the carbohydrate moieties of
    glycolipids on the surface of cells as well as the carbohydrate portion
    of serum glycoproteins. When present on the surface of cells the ABO
    carbohydrates are linked to sphingolipid and are therefore of the
    glycosphingolipid class. When the ABO carbohydrates are associated with
    protein in the form of glycoproteins they are found in the serum and are
    referred to as the secreted forms. Some individuals produce the
    glycoprotein forms of the ABO antigens while others do not. This
    property distinguishes secretors from non-secretors, a property that has
    forensic importance such as in cases of rape."
    http://web.indstate.edu/thcme/mwking/lipid-synthesis.html
    See the graphic below the exerpt above for a more complete explanation.
    The first 4 of the following are types of sugars:
    GlcNAc, galactose, fucose, GalNAc, and sialic acid (NANA)

    Using the search term diet in the journal Glycobiology there were 18
    finds - http://tinyurl.com/5289g

    Using the search term ABO in the journal Glycobiology there were 68
    finds http://tinyurl.com/4mxwe

    A High-Wire multiple journal search turned up 4,999 finds for ABO -
    http://tinyurl.com/5qsnm. It is not a simple subject.

    "The clinical use of genomic blood grouping in transfusion medicine
    practice has evolved during the past decade as a result of the cloning
    of most blood group genes. A recent review 43 outlined different
    situations in the clinical laboratory where blood group genotyping may
    be valuable and ABO genotyping has been used for many of them, although
    acquired and inherited variant phenotypes are probably the most important.

    Frank

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