This problem is driving my absolutely nuts.
I needed a new chain on my bike, and I figured as long as I was getting a new chain, I'd get a new cassette and put my old cassette on a spare wheel I have (to use on the trainer). I had a Tiagra 9-speed chain and a Tiagra cassette, 12-25 and everything working well.
I bought a Sram PC991 9-speed chain and an Ultegra 9-speed cassette, also 12-25. First I put the new chain on, lubed it up, and it worked flawlessly (with the old Tiagra cassette). Next, I installed the new Ultegra cassette, and in certain gear combinations, the cassette is noisy and causes vibrations. The vibration is not constant, but happens about 3 or 4 times per pedal stroke. It's like I can feel the drivetrain in the pedals as I pedal.
I have a triple, and when I am in the middle ring up front, and in one of the middle cogs, everything is smooth. When I start to get into the higher gears (i.e., smaller cogs), things start to get noisy and less smooth. When I am in the big ring up front, the middle cogs are fine, but when I get into the top 3 gears, everthing is very rough. Especially the 53-12 combo--it's very noisy and the pulsations are quite strong.
The indexing does not affect the problem at all. I tried the b-screw and the limit screws--everything looks fine. I put the old cassette back on, and the problem goes away. I torqued the cassette down at 40Nm. I also tried tightening it a little--no change. The derailleur hanger looks fine, too.
I don't know what else to do... Is it possible I need to break in the cassette a little?
Thanks.