MUSCLE IMPLANTS!!!!

Prisoner at War said:

The Beep reported on Thursday that scientists have been making muscle
in the lab, which they then implant into rats with great results!
Human trials are scheduled soon....

They do it by mixing some muscle cells with a very thin film of some
sort...they're not doing skeletal muscles, but smooth muscles such as
what make up the heart and other organs -- but can skeletal muscles be
far behind??

WOW!!! Imagine, finally -- just replace that ageing biceps with new
ones!!!

America needs a process that turns fat into muscle tissue!

chatnoir said:

Prisoner at War said:

The Beep reported on Thursday that scientists have been making muscle
in the lab, which they then implant into rats with great results! Human
trials are scheduled soon....

They do it by mixing some muscle cells with a very thin film of some
sort...they're not doing skeletal muscles, but smooth muscles such as
what make up the heart and other organs

The heart isn't smooth muscle. Smooth muscle is what wraps your blood
vessels, gut, bladder, etc - it generates long, slow contractions to
maintain static pressure. If your heart was smooth muscle, it'd beat about
once every ten seconds.

The heart is cardiac muscle - something different to both smooth and
skeletal muscle, but much more similar to skeletal than smooth, in terms
of ultrastructure, regulation, etc. Smooth muscle cells are actually a lot
more similar to contractile non-muscle cells than they are to the other
muscle cells in those respects; the isoforms of myosin etc they use are
also either the same as or closely related to the non-muscle isoforms.

Quoted message said:

Quoted message said:

-- but can skeletal muscles be far behind??

Skeletal muscle is pretty different to smooth muscle - it has a lot more
structure, so it'll be harder to make. You can't just mix up cultured
cells and some laminin or whatever and expect it to work. But, it's
probably not impossible. The right goop, the right growth factors, maybe
some sort of microstructured scaffold ...

Quoted message said:

Quoted message said:

WOW!!! Imagine, finally -- just replace that ageing biceps with new
ones!!!

America needs a process that turns fat into muscle tissue!

Not as absurd as you might think. Adipocytes and muscles cells are close
to each other in the family tree of cell types, so you only have to
persuade a fat cell to dedifferentiate a few steps back to a mesenchymal
stem cell (currently entirely impossible) before it's good to turn into
a muscle cell.

But then you get muscles forming in some pretty weird places. Subcutaneous
fat becoming subcutaneous muscle? Er, no thanks. Unless you can figure out
a way to make the stem cells move to the right place - like a metastasing
cancer cell. Sounds great! And they'd have to move quite some distance,
otherwise i'm going to have the most muscular [censored] this side of one of
Pete's wet dreams, and abs bigger than my pecs.

tom

--
power to the people and the beats

Tom Anderson <[email hidden]> wrote in
news:[email hidden]:

Quoted message said:

chatnoir said:

Prisoner at War said:

The Beep reported on Thursday that scientists have been making
muscle in the lab, which they then implant into rats with great
results! Human trials are scheduled soon....

They do it by mixing some muscle cells with a very thin film of some
sort...they're not doing skeletal muscles, but smooth muscles such
as what make up the heart and other organs

The heart isn't smooth muscle. Smooth muscle is what wraps your blood
vessels, gut, bladder, etc - it generates long, slow contractions to
maintain static pressure. If your heart was smooth muscle, it'd beat
about once every ten seconds.

The heart is cardiac muscle - something different to both smooth and
skeletal muscle, but much more similar to skeletal than smooth, in
terms of ultrastructure, regulation, etc. Smooth muscle cells are
actually a lot more similar to contractile non-muscle cells than they
are to the other muscle cells in those respects; the isoforms of
myosin etc they use are also either the same as or closely related to
the non-muscle isoforms.

Quoted message said:

Quoted message said:

-- but can skeletal muscles be far behind??

Skeletal muscle is pretty different to smooth muscle - it has a lot
more structure, so it'll be harder to make. You can't just mix up
cultured cells and some laminin or whatever and expect it to work.
But, it's probably not impossible. The right goop, the right growth
factors, maybe some sort of microstructured scaffold ...

Quoted message said:

Quoted message said:

WOW!!! Imagine, finally -- just replace that ageing biceps with new
ones!!!

America needs a process that turns fat into muscle tissue!

Not as absurd as you might think. Adipocytes and muscles cells are
close to each other in the family tree of cell types, so you only have
to persuade a fat cell to dedifferentiate a few steps back to a
mesenchymal stem cell (currently entirely impossible) before it's good
to turn into a muscle cell.

But then you get muscles forming in some pretty weird places.
Subcutaneous fat becoming subcutaneous muscle? Er, no thanks. Unless
you can figure out a way to make the stem cells move to the right
place - like a metastasing cancer cell. Sounds great! And they'd have
to move quite some distance, otherwise i'm going to have the most
muscular [censored] this side of one of Pete's wet dreams, and abs bigger
than my pecs.

tom

Man, I wish I'd have had some muscle implants before I made my flexing
video. I would have looked so hot. I would have rubbed myself down
with baby oil and worn a speeo.

I'm now thinking of getting a butt lift, for the next time I take
pictures of my own butt, I'd have something to be REALLY proud of.

Thanks for the news

--
Bill Davidson

I removed the picture of my butt from the website, because I
wanted to take some better ones, maybe with me inserting
some toys. For now, here are pictures I took while stalking
sunbathers here:

http://s88.photobucket.com/albums/k170/bagpip1/Beach/

In article <[email hidden]>,

Prisoner at War said:

The Beep reported on Thursday that scientists have been making muscle
in the lab, which they then implant into rats with great results!
Human trials are scheduled soon....

They do it by mixing some muscle cells with a very thin film of some
sort...they're not doing skeletal muscles, but smooth muscles such as
what make up the heart and other organs -- but can skeletal muscles be
far behind??

WOW!!! Imagine, finally -- just replace that ageing biceps with new
ones!!!

Or growing cuter ears:

http://www.madsci.org/posts/archives/2003-12/1070561342.Gb.r.html
--
Peace, Om

Remove _ to validate e-mails.

"My mother never saw the irony in calling me a Son of a [censored]" -- Jack Nicholson

Say, how do you work this google thingamajig, anyway...couldn't pull
up anything using the search terms "bbc muscle film rats implants
new"....

And didn't somebody else grow chicken meat in the lab or something
last year???

Omelet said:

In article <[email hidden]>,

Or growing cuter ears:

http://www.madsci.org/posts/archives/2003-12/1070561342.Gb.r.html
--
Peace, Om

Remove _ to validate e-mails.

"My mother never saw the irony in calling me a Son of a [censored]" -- Jack Nicholson

In article <[email hidden]>,

Prisoner at War said:

Omelet said:

In article <[email hidden]>,

Or growing cuter ears:

http://www.madsci.org/posts/archives/2003-12/1070561342.Gb.r.html

Say, how do you work this google thingamajig, anyway...couldn't pull
up anything using the search terms "bbc muscle film rats implants
new"....

And didn't somebody else grow chicken meat in the lab or something
last year???

It's all in the key words... I already knew about them trying to grow
noses and ears on the backs of mice and rats for plastic surgery, so I
just typed in "ear growing on a rats back" for my google search.

If one search chain does not work, try something a bit different.

Sometimes it takes some patience to find what you want. There are
literally billions of websites.

Besides, my reply to you was meant to be funny.
Perhaps you need to transplant a sense of humor. ;-)

In all seriousness, I doubt that "Muscle implants" will be useful for
body building any time soon. They are more applicable to people that
have been in serious accidents and need re-building.

On the up-side, prosthetic muscle implants have been available for years
for physique enhancement. Please note that they won't make you stronger,
just "prettier". <G>

Try here to start:

http://www.onlinesurgery.com/plasticsurgery/calf-implants.asp

There is a side bar with other procedures.
--
Peace, Om

Remove _ to validate e-mails.

"My mother never saw the irony in calling me a Son of a [censored]" -- Jack Nicholson

Tom Anderson said:

The heart isn't smooth muscle.

You're right -- I didn't mean to mention them in the same breath like
that; thanks for the correction.

Quoted message said:

Smooth muscle is what wraps your blood
vessels, gut, bladder, etc - it generates long, slow contractions to
maintain static pressure. If your heart was smooth muscle, it'd beat about
once every ten seconds.

Hmm! Is the brain smooth muscle? No, seriously!

Quoted message said:

The heart is cardiac muscle - something different to both smooth and
skeletal muscle, but much more similar to skeletal than smooth, in terms
of ultrastructure, regulation, etc. Smooth muscle cells are actually a lot
more similar to contractile non-muscle cells than they are to the other
muscle cells in those respects; the isoforms of myosin etc they use are
also either the same as or closely related to the non-muscle isoforms.

I wonder if bugs or lobsters have the same kind of muscles inside
their exoskeletons....

Quoted message said:

Skeletal muscle is pretty different to smooth muscle - it has a lot more
structure, so it'll be harder to make. You can't just mix up cultured
cells and some laminin or whatever and expect it to work. But, it's
probably not impossible. The right goop, the right growth factors, maybe
some sort of microstructured scaffold ...

That's the thing...the Beep reported that it did work in rats, and
that they're going to do human trials soon...I wish I could post a
link, but I heard this on the radio, and I just didn't have any luck
with the search terms "BBC muscle film implant rats"....

Quoted message said:

Not as absurd as you might think. Adipocytes and muscles cells are close
to each other in the family tree of cell types, so you only have to
persuade a fat cell to dedifferentiate a few steps back to a mesenchymal
stem cell (currently entirely impossible) before it's good to turn into
a muscle cell.

Heck, just find out what biochemical signals causes fat burning,
explore any safety issues involved....

Quoted message said:

But then you get muscles forming in some pretty weird places. Subcutaneous
fat becoming subcutaneous muscle? Er, no thanks. Unless you can figure out
a way to make the stem cells move to the right place - like a metastasing
cancer cell. Sounds great! And they'd have to move quite some distance,
otherwise i'm going to have the most muscular [censored] this side of one of
Pete's wet dreams, and abs bigger than my pecs.

Whatever happened to that electrostimulation stuff? Did it not work,
or not work very well, or had serious side-effects?

Quoted message said:

tom

--
power to the people and the beats

Omelet said:

It's all in the key words... I already knew about them trying to grow
noses and ears on the backs of mice and rats for plastic surgery, so I
just typed in "ear growing on a rats back" for my google search.

If one search chain does not work, try something a bit different.

Are you and Curt big time Scrabble players or something?? What else
could I have used...I just don't get it...I mean, it's the BBC, for
Christ's sake, and their own search engine doesn't pull "muscle
implant film scientists" up on their site...what the heck....

Quoted message said:

Sometimes it takes some patience to find what you want. There are
literally billions of websites.

They say that, but it's like the night sky here in NYC: I can only
ever see so many, and even those are more likely to be satellites or
even airplanes! There are a bunch of newsgroups out there on weights,
I bet, but googlegroups seems to only turn up MFW!!!

Quoted message said:

Besides, my reply to you was meant to be funny.
Perhaps you need to transplant a sense of humor. ;-)

Funny bone transplants for autistic weightlifters, eh?

Actually, I wasn't even sure if what you'd linked was a spoof or what!

Quoted message said:

In all seriousness, I doubt that "Muscle implants" will be useful for
body building any time soon. They are more applicable to people that
have been in serious accidents and need re-building.

Oh, yes, right: but it's coming! Just in time for my
retirement...ah....maybe growing old won't suck so bad by the time I
get there...I'll have my eyeballs replaced, my superficial muscles
upgraded, maybe even my teeth regrown!!!

Quoted message said:

On the up-side, prosthetic muscle implants have been available for years
for physique enhancement. Please note that they won't make you stronger,
just "prettier". <G>

Try here to start:

http://www.onlinesurgery.com/plasticsurgery/calf-implants.asp

There is a side bar with other procedures.

How amusing! Who the heck uses these services??

Quoted message said:

--
Peace, Om

Remove _ to validate e-mails.

"My mother never saw the irony in calling me a Son of a [censored]" -- Jack Nicholson

Prisoner at War said:

Tom Anderson said:

Smooth muscle is what wraps your blood vessels, gut, bladder, etc - it
generates long, slow contractions to maintain static pressure. If your
heart was smooth muscle, it'd beat about once every ten seconds.

Hmm! Is the brain smooth muscle? No, seriously!

No.

Quoted message said:

Quoted message said:

The heart is cardiac muscle - something different to both smooth and
skeletal muscle, but much more similar to skeletal than smooth, in
terms of ultrastructure, regulation, etc. Smooth muscle cells are
actually a lot more similar to contractile non-muscle cells than they
are to the other muscle cells in those respects; the isoforms of myosin
etc they use are also either the same as or closely related to the
non-muscle isoforms.

I wonder if bugs or lobsters have the same kind of muscles inside their
exoskeletons....

They do.

The simplest animals don't - jellyfish only have smooth muscle, and some
sort of hybrid epithelial-muscle cell (epithelial cells being what makes
up your skin, the lining of your gut, etc). I have no idea where in the
tree of life skeletal muscle evolved.

Quoted message said:

Quoted message said:

Skeletal muscle is pretty different to smooth muscle - it has a lot
more structure, so it'll be harder to make. You can't just mix up
cultured cells and some laminin or whatever and expect it to work. But,
it's probably not impossible. The right goop, the right growth factors,
maybe some sort of microstructured scaffold ...

That's the thing...the Beep reported that it did work in rats, and that
they're going to do human trials soon...I wish I could post a link, but
I heard this on the radio, and I just didn't have any luck with the
search terms "BBC muscle film implant rats"....

Me neither.

Quoted message said:

Quoted message said:

Not as absurd as you might think. Adipocytes and muscles cells are
close to each other in the family tree of cell types, so you only have
to persuade a fat cell to dedifferentiate a few steps back to a
mesenchymal stem cell (currently entirely impossible) before it's good
to turn into a muscle cell.

Heck, just find out what biochemical signals causes fat burning,
explore any safety issues involved....

Dinitrophenol, plus plenty of water, vitamin C and air conditioning.

tom

--
I burning your dog.

In article <[email hidden]>,

Prisoner at War said:

Omelet said:

It's all in the key words... I already knew about them trying to grow
noses and ears on the backs of mice and rats for plastic surgery, so I
just typed in "ear growing on a rats back" for my google search.

If one search chain does not work, try something a bit different.

Are you and Curt big time Scrabble players or something?? What else
could I have used...I just don't get it...I mean, it's the BBC, for
Christ's sake, and their own search engine doesn't pull "muscle
implant film scientists" up on their site...what the heck....

BBC is not omnipotent. ;-)

Quoted message said:

Quoted message said:

Sometimes it takes some patience to find what you want. There are
literally billions of websites.

They say that, but it's like the night sky here in NYC: I can only
ever see so many, and even those are more likely to be satellites or
even airplanes! There are a bunch of newsgroups out there on weights,
I bet, but googlegroups seems to only turn up MFW!!!

<lol> Not surprised. I'm a bit tired right now, an hour past my bedtime
and I do have to work tonight or I'd play on Google.

Ask Curt to try. He's better at it than I am.

Quoted message said:

Quoted message said:

Besides, my reply to you was meant to be funny.
Perhaps you need to transplant a sense of humor. ;-)

Funny bone transplants for autistic weightlifters, eh?

<lol> Humor makes life worth living.

Quoted message said:

Actually, I wasn't even sure if what you'd linked was a spoof or what!

Well, it did highlight the fact that tissue transplant research is very
real.

Quoted message said:

Quoted message said:

In all seriousness, I doubt that "Muscle implants" will be useful for
body building any time soon. They are more applicable to people that
have been in serious accidents and need re-building.

Oh, yes, right: but it's coming! Just in time for my
retirement...ah....maybe growing old won't suck so bad by the time I
get there...I'll have my eyeballs replaced, my superficial muscles
upgraded, maybe even my teeth regrown!!!

Dude. Just do what the rest of us do. Eat right, sleep good and lift
heavy things.

And be patient.

Your own body is the best science factory there is.
You will get better benefits if you don't have to have it all NOW NOW
NOW.

Honestly!

Quoted message said:

Quoted message said:

On the up-side, prosthetic muscle implants have been available for years
for physique enhancement. Please note that they won't make you stronger,
just "prettier". <G>

Try here to start:

http://www.onlinesurgery.com/plasticsurgery/calf-implants.asp

There is a side bar with other procedures.

How amusing! Who the heck uses these services??

Heh! You'd be surprised...
If nobody used them, they'd not spend the money making, or advertise
them.
--
Peace, Om

Remove _ to validate e-mails.

"My mother never saw the irony in calling me a Son of a [censored]" -- Jack Nicholson

In article <[email hidden]>,

Tom Anderson said:

Quoted message said:

Heck, just find out what biochemical signals causes fat burning,
explore any safety issues involved....

Dinitrophenol, plus plenty of water, vitamin C and air conditioning.

tom

Nice one. ;-)
--
Peace, Om

Remove _ to validate e-mails.

"My mother never saw the irony in calling me a Son of a [censored]" -- Jack Nicholson

Prisoner at War said:

The Beep reported on Thursday that scientists have been making muscle
in the lab, which they then implant into rats with great results!
Human trials are scheduled soon....

They do it by mixing some muscle cells with a very thin film of some
sort...they're not doing skeletal muscles, but smooth muscles such as
what make up the heart and other organs -- but can skeletal muscles be
far behind??

WOW!!! Imagine, finally -- just replace that ageing biceps with new
ones!!!

It may be of help to people who already have functioning muscles and
just want to build them up again, but it doesn't offer hope for those
who have permanent paralysis in that muscle..it won't help to replace
the muscle as it too would just atrophy without being hooked up to the
central nervous system.
this is just my opinion as one who lives with paralysis.

Tom Anderson said:

chatnoir said:

Prisoner at War wrote:

Quoted message said:

Quoted message said:

The Beep reported on Thursday that scientists have been making muscle
in the lab, which they then implant into rats with great results! Human
trials are scheduled soon....

Quoted message said:

Quoted message said:

They do it by mixing some muscle cells with a very thin film of some
sort...they're not doing skeletal muscles, but smooth muscles such as
what make up the heart and other organs

The heart isn't smooth muscle. Smooth muscle is what wraps your blood
vessels, gut, bladder, etc - it generates long, slow contractions to
maintain static pressure. If your heart was smooth muscle, it'd beat about
once every ten seconds.

The heart is cardiac muscle - something different to both smooth and
skeletal muscle, but much more similar to skeletal than smooth, in terms
of ultrastructure, regulation, etc. Smooth muscle cells are actually a lot
more similar to contractile non-muscle cells than they are to the other
muscle cells in those respects; the isoforms of myosin etc they use are
also either the same as or closely related to the non-muscle isoforms.

Quoted message said:

Quoted message said:

-- but can skeletal muscles be far behind??

Skeletal muscle is pretty different to smooth muscle - it has a lot more
structure, so it'll be harder to make. You can't just mix up cultured
cells and some laminin or whatever and expect it to work. But, it's
probably not impossible. The right goop, the right growth factors, maybe
some sort of microstructured scaffold ...

Quoted message said:

Quoted message said:

WOW!!! Imagine, finally -- just replace that ageing biceps with new
ones!!!

Quoted message said:

America needs a process that turns fat into muscle tissue!

Not as absurd as you might think. Adipocytes and muscles cells are close
to each other in the family tree of cell types, so you only have to
persuade a fat cell to dedifferentiate a few steps back to a mesenchymal
stem cell (currently entirely impossible) before it's good to turn into
a muscle cell.

But then you get muscles forming in some pretty weird places. Subcutaneous
fat becoming subcutaneous muscle? Er, no thanks. Unless you can figure out
a way to make the stem cells move to the right place - like a metastasing
cancer cell. Sounds great! And they'd have to move quite some distance,
otherwise i'm going to have the most muscular [censored] this side of one of
Pete's wet dreams, and abs bigger than my pecs.

tom

Beats Diabetes