Metformin & Pregnancy

"eso" <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

Hi,

can anybody please tell me the latest news about the use
of metformin in pregnancy?

I read about a high after-birth mortality rate in a study
in Denmark in 2000. Are there any similar or contrary
newer results?

I live in Germany, where metformin is not used in
pregnancy. So if I'm able to persuade my doctor to
continue metformin I need answers to these questions:
* What does she have to pay attention for? What data
should be under control?
* How much metformin can/should I use? Before pregnancy I
took 1000 mg per day.

Thank you very very much for your answers!!!

As far as I know, there is no diabetes medication that is
considered safe to be used during pregnancy. Here in the US,
insulin is used if needed.

--
Type 2 users.bestweb.net~jboveOpen ↗

eso wrote in message ...

Quoted message said:

Hi,

can anybody please tell me the latest news about the use of
metformin in pregnancy?

I read about a high after-birth mortality rate in a study
in Denmark in 2000. Are there any similar or contrary
newer results?

I live in Germany, where metformin is not used in
pregnancy. So if I'm able to persuade my doctor to continue
metformin I need answers to these questions:
* What does she have to pay attention for? What data should
be under control?
* How much metformin can/should I use? Before pregnancy I
took 1000 mg per day.

Thank you very very much for your answers!!!

eso

I have seen references to a desire to test to see if
metformin is allowable in pregnancy but never any results
of such tests.

Taking drugs during pregnancy can be very dangerous. The
doctors hate to give any drug to pregnant women. Very
few of them are willing to break new ground. I don't
blame them.

The best docs demand that their pregnant diabetics go on
insulin if they start to see blood sugars above 120 mg/dL
(6.7 mmol/L) at any time for any reason! This is a time
for you to test your blood sugar more often to see if
your baby needs you to inject insulin.

That's "need" insulin, not "want", "desire", "use it to
make the doc happy", etc, etc. If your sugars start to
spike over 120 mg/dL, your baby needs the protection of
insulin injections.

Sorry, but insulin injections are excellent therapy for Type
2 diabetics at any time for any reason. They always work,
they do wonders for your long term health and safety. Sounds
like a horrible idea. (I just about threw up when I found
out that I might need insulin) However, once you try a few,
you wonder why you disliked the idea.

Regards
Old Al

Interesting.

I have heard that Metformin can actually help prevent
miscarriage and help in conception for those with diabetes
and polycystic ovarian syndrome (which alot of times causes
diabetes in women.)

I have 2 friends who are insulin-resistant diabetics and
suffer from polycystic ovarian syndrome (which caused the
diabetes), and were having extreme difficulty in having
children, from the hormonal problems and all. So, they were
told to try metformin, to help decrease diabetic and
polycystic symptoms and also in new studies have found that
it actually helps keep things normalized during pregnancy,
thus, decreasing chances of miscarriages and helps increase
ovulation for those who have a lack of ovulation.

Anyways, my 2 friends both had pasts of miscarriages and
years of fertility drugs and therapies... until metformin.
now both have both given birth to healthy kids and are
healthy themselves since on the med.

but.... it effects everyone differently.

i still say, depends on what the doc says. always a risk.

[email hidden] (porkchops) wrote in message news:<[email hidden]>...

Quoted message said:

Interesting.

I have heard that Metformin can actually help prevent
miscarriage and help in conception for those with diabetes
and polycystic ovarian syndrome (which alot of times
causes diabetes in women.)

I have 2 friends who are insulin-resistant diabetics and
suffer from polycystic ovarian syndrome (which caused the
diabetes), and were having extreme difficulty in having
children, from the hormonal problems and all. So, they
were told to try metformin, to help decrease diabetic and
polycystic symptoms and also in new studies have found
that it actually helps keep things normalized during
pregnancy, thus, decreasing chances of miscarriages and
helps increase ovulation for those who have a lack of
ovulation.

Anyways, my 2 friends both had pasts of miscarriages and
years of fertility drugs and therapies... until metformin.
now both have both given birth to healthy kids and are
healthy themselves since on the med.

but.... it effects everyone differently.

i still say, depends on what the doc says. always a risk.

Thank you all very much for your answers!

Yes, I am a PCO-diabetic too and became pregnant with help
of metformin. It's my second pregnancy. The first one was
horrible. I took insuline. But insuline makes hungry. And in
a pregnancy you are always hungry anyway. When I ate more I
had to take more insuline - and were hungry again. I was
hungry all the time since I started taking insuline. To be
hungry was not only the unpleasant feeling - I could'nt
sleep very well too.

So I was very happy when I read, that in some studies in US
metformin was successfully given to pregnant diabetics. I
started to hope for a better second pregnancy. But I also
read about a high after-birth mortality rate of babies in a
danish metformin-study :-(((

porkchops, could you please tell me more about the
pregnancies of your friends?

eso

[email hidden] (eso) wrote in message news:<[email hidden]>...

Quoted message said:

porkchops, could you please tell me more about the
pregnancies of your friends?

eso

The failed or successful ones?

Well, after they went on metformin, everything went well.
Before that, everything went nuts due to constantly
fluctuating hormonal problems and extremely high
testerosterone due to the PCOS, which was making everything
worse. My one friend developed internal rupturing due to a
cyst in the uterus as well which they linked with hormonal
issues. They could not go on the pill obviously, to help the
hormones or other meds, it was too risky. With metformin,
their sugars and insulins remained balanced and even helped
keep the hormones in better order (they believe the actual
PCOS was caused by the diabetes perhaps, instead of the
other way aroud. There's debate on this in the medical
field.) And while the insulins and sugars were being kept in
balance, oddly, the testosterone and other hormones remained
in better balance and more predictable and the babies were
healthy. of course they needed extra care and precaution.

As for future problems in the child, to develop after the
mother takes metformin during pregnancy occuring.. no one
really knows yet. There appears to be no problems in
studies done.

I, also have PCOS and am on metformin to keep my insulins
normal and also on the pill.. and it's helped me. I am not
trying to get pregnant nor ever have. They say that some
people with PCOS who take the pill to keep from having the
severe symptoms can just remain on the metformin and
sometimes this alone can .. sort of reverse the PCOS. This
is usually due to the diabetes causing the PCOS, instead of
the PCOS causing the diabetes, but, the insulin alone can
cause serious hormonal imbalances in other ways too. So, I
guess it works either way. When and if I ever wanna get
pregnant, I will have to go off the pill, and God only knows
what would happen then. It's scary to me to think of.
However, I will still have the metformin. I have known
people who have claimed that they have been able to go
completely off the pill and stay on metformin and it does
the job itself.

Like I said, it miught not work as well with women who are
trying to get pregnant/keep the pregnancy. Each woman is
different, each hormonal order is different, each pregnancy
is different, each period is different. But it appears that
in the whole picture of it all, metformin's safe and a total
godsend. I cant really see it doing any bad.

I will be happy to answer any other questions you may have.

Pork.