Low-carb eating & triglycerides

Chad C. said:

Does the substantial reduction in trigylcerides in the
blood from following a low-carb eating plan (about 50% fat
calories, 25% protein calories, 25% low-glycemic
carbohydrate calories) result in a decreased long-term
risk for heart disease?

Ime, no.

Quoted message said:

Blood lipid tests pretty clearly show triglycerides
reducing by about half on average for most people. I want
to know the implications of this over the long haul.

Ime, heart disease worsens in folks trying to lose weight
with the low-carb approach.

Quoted message said:

Thanks!

You are welcome, Chad :-)

Servant to the humblest person in the universe,

Andrew

--
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Board-Certified Cardiologist
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x-no-archive: yes

Quoted message said:

Does the substantial reduction in trigylcerides in the
blood from following a low-carb eating plan (about 50% fat
calories, 25% protein calories, 25% low-glycemic
carbohydrate calories) result in a decreased long-term risk
for heart disease? Blood lipid tests pretty clearly show
triglycerides reducing by about half on average for most
people. I want to know the implications of this over the
long haul.

Thanks!

-Chad

Triglycerides are an independent risk factor, some
researchers believe TGL to be a more accurate
predictor of CVD:

"A new study suggests that level of triglyceride in the
blood may help predict heart attack risk as well as other
more well-known blood fats such as LDL and HDL
cholesterol. High triglycerides alone increased the risk
of heart attack nearly three-fold, according to a report
in the current issue of Circulation. And people with the
highest ratio of triglycerides to HDL -- the "good"
cholesterol -- had 16 times the risk of heart attack as
those with the lowest ratio of triglycerides to HDL in the
study of 340 heart attack patients and 340 of their
healthy, same age counterparts. The ratio of triglycerides
to HDL was the strongest predictor of a heart attack, even
more accurate than the
LDL/HDL ratio," reported Harvard lead study author.
Triglycerides, a mixture of fatty acids and
glycerol that make up the principle fats in the
blood, bind to carrier proteins, forming compounds
known as lipoproteins. Other types of lipoproteins
that carry cholesterol, such as LDL and HDL, are
known to be related to the risk of heart disease
because of their propensity to deposit -- or not
deposit -- fat in coronary arteries. However, it
has not been clear if triglyceride level could
predict heart attack risk, despite years of
research." Circulation (1997;96:2520-2525)

Susan

Hi Andrew,

Could you please elucidate your reasoning?

Thanks!

-Chad

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote
in message "]news:[email hidden]...

Quoted message said:

Chad C. said:

Does the substantial reduction in trigylcerides in the
blood from

following

Quoted message said:

Quoted message said:

a low-carb eating plan (about 50% fat calories, 25%
protein calories,

25%

Quoted message said:

Quoted message said:

low-glycemic carbohydrate calories) result in a
decreased long-term risk

for

Quoted message said:

Quoted message said:

heart disease?

Ime, no.

Quoted message said:

Blood lipid tests pretty clearly show triglycerides
reducing by about half on average for most people. I
want to know the

implications of

Quoted message said:

Quoted message said:

this over the long haul.

Ime, heart disease worsens in folks trying to lose weight
with the

low-carb

Quoted message said:

approach.

Quoted message said:

Thanks!

You are welcome, Chad :-)

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

** Who is the humblest person in the universe?
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What is all this about?
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Chad C. said:

Hi Andrew,

Could you please elucidate your reasoning?

One possible explanation for what I have observed is what
happens at a molecular level when someone has hyperketonemia
from being carb deficient.

This has been discussed before here at SMC and should be
archived in Google.

Google keywords:

hyperketonemia, Barry Sears, Atkins

Quoted message said:

Thanks!

You are welcome, Chad :-)

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

**
Who is the humblest person in the universe?
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What is all this about?
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Dr. Andrew B. Chung said:

Chad C. said:

Hi Andrew,

Could you please elucidate your reasoning?

One possible explanation for what I have observed is what
happens at a molecular level when someone has
hyperketonemia from being carb deficient.

This has been discussed before here at SMC and should be
archived in Google.

This has been discussed, but almost always with the premise
of hyperketonemia as the permanent condition. Reduced carbs
doesn't necessarily cause any sorts of ketotic conditions;
it varies from person to person.

Go over to alt.support.diet.low-carb and ask the same
question. Lots of people with very specific information
about it; lots of experience. The FAQ is posted every day
and has lots of good leads to investigate.

Bob

Quoted message said:

Google keywords:

hyperketonemia, Barry Sears, Atkins

Well, what about this explanation:

High TG and low HDL indicates insulin resistance. The most
obvious symptom of insulin resistance is of course highly
increased insulin levels in blood and unstable blood sugar.
Both are highly atherogenic.

So maybe TG/HDL ration is nothing else than indicator of
insulin resistance. As TG and HDL are related with general
dislipidemia and high TC as well, it would simply explain
most results of Farmingham stdies, failed results of non-
statin TC reduction drugs, failed results of low-fat mania
etc, etc...

In this context low-carb would indeed be benefical, as it
should improve both BG stability and reduce insulin
secretion - and this would be demonstrated in improved TG
and HDL levels.

As for dr. Chung's (and Barry Sear's) concerns about lipid
peroxidation due to ketonemia, well, in very deep ketosis or
ketoacidosis it really might happen. In any case it is
better to stay away from deep ketosis and to suplement with
E vitamin to prevent peroxidation.

Speaking about it, many consider The Zone to be the low-carb
plan. South-Beach promotes itself as non-ketogenic from the
day one. Atkins is ketogenic, but when followed as written
it should lead you on the "edge" of ketosis (around 50g
carbs a day). That is as ketogenic as fasting for 24 hours.

Mirek

"Susan " <[email hidden]> pí¹e v diskusním pøíspìvku
"]news:[email hidden]...

Quoted message said:

x-no-archive: yes

Quoted message said:

Does the substantial reduction in trigylcerides in the
blood from

following

Quoted message said:

Quoted message said:

a low-carb eating plan (about 50% fat calories, 25%
protein calories,

25%

Quoted message said:

Quoted message said:

low-glycemic carbohydrate calories) result in a decreased
long-term

risk for

Quoted message said:

Quoted message said:

heart disease? Blood lipid tests pretty clearly show
triglycerides

reducing

Quoted message said:

Quoted message said:

by about half on average for most people. I want to
know the

implications of

Quoted message said:

Quoted message said:

this over the long haul.

Thanks!

-Chad

Triglycerides are an independent risk factor, some
researchers believe

TGL to

Quoted message said:

be a more accurate predictor of CVD:

"A new study suggests that level of triglyceride in the
blood may help predict heart attack risk as well as other
more well-known blood fats such as LDL and HDL
cholesterol. High triglycerides alone increased the risk
of heart attack nearly three-fold, according to a report
in the current issue of Circulation. And people with the
highest ratio of triglycerides to HDL -- the "good"
cholesterol -- had 16 times the risk of heart attack as
those with the lowest ratio of triglycerides to HDL in the
study of 340 heart attack patients and 340 of their
healthy, same age counterparts. The ratio of triglycerides
to HDL was the strongest predictor of a heart attack, even
more accurate than the
LDL/HDL ratio," reported Harvard lead study author.
Triglycerides, a mixture of fatty acids and glycerol
that make up the principle fats in the blood, bind to
carrier proteins, forming compounds known as
lipoproteins. Other types of lipoproteins that carry
cholesterol, such as LDL and HDL, are known to be
related to the risk of heart disease because of their
propensity to deposit -- or not deposit -- fat in
coronary arteries. However, it has not been clear if
triglyceride level could predict heart attack risk,
despite years of research." Circulation (1997;96:2520-
2525)

Susan

"Mirek Fidler" <[email hidden]> wrote in message news:<[email hidden]>...

Quoted message said:

Well, what about this explanation:

High TG and low HDL indicates insulin resistance. The most
obvious symptom of insulin resistance is of course highly
increased insulin levels in blood and unstable blood
sugar. Both are highly atherogenic.

So maybe TG/HDL ration is nothing else than indicator of
insulin resistance. As TG and HDL are related with general
dislipidemia and high TC as well, it would simply explain
most results of Farmingham stdies, failed results of non-
statin TC reduction drugs, failed results of low-fat mania
etc, etc...

In this context low-carb would indeed be benefical, as it
should improve both BG stability and reduce insulin
secretion - and this would be demonstrated in improved TG
and HDL levels.

As for dr. Chung's (and Barry Sear's) concerns about lipid
peroxidation due to ketonemia, well, in very deep ketosis
or ketoacidosis it really might happen. In any case it is
better to stay away from deep ketosis and to suplement
with E vitamin to prevent peroxidation.

Speaking about it, many consider The Zone to be the low-
carb plan. South-Beach promotes itself as non-ketogenic
from the day one. Atkins is ketogenic, but when followed
as written it should lead you on the "edge" of ketosis
(around 50g carbs a day). That is as ketogenic as fasting
for 24 hours.

Mirek

Salut Mirek

I invite you to comment on my posts (elsewhere) in this
thread regarding my cholesterol levels. I won't repeat the
information here. Jim Chinnis has found something very
interesting relative to my experience of the past several
months. And, some of the links Al Lohse has posted have some
relation to what Jim has found.

Zee

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

Chad C. said:

Hi Andrew,

Could you please elucidate your reasoning?

One possible explanation for what I have observed is what
happens at a

molecular

Quoted message said:

level when someone has hyperketonemia from being carb
deficient.

This has been discussed before here at SMC and should be
archived in

Google.

Quoted message said:

Google keywords:

hyperketonemia, Barry Sears, Atkins

Andrew:

I always find it a tad disturbing to see Sears and Atkins
compared. I think Sears is so much more balanced than
Atkins. Do you not agree?

j

Quoted message said:

Quoted message said:

Thanks!

You are welcome, Chad :-)

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

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Julianne said:

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]>
wrote in message "]news:[email hidden]...

Quoted message said:

Chad C. said:

Hi Andrew,

Could you please elucidate your reasoning?

One possible explanation for what I have observed is
what happens at a

molecular

Quoted message said:

level when someone has hyperketonemia from being carb
deficient.

This has been discussed before here at SMC and should be
archived in

Google.

Quoted message said:

Google keywords:

hyperketonemia, Barry Sears, Atkins

Andrew:

I always find it a tad disturbing to see Sears and Atkins
compared. I think Sears is so much more balanced than
Atkins. Do you not agree?

j

Yes.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

**
Who is the humblest person in the universe?
makeashorterlink.commakeashorterlink.comOpen ↗

What is all this about?
makeashorterlink.commakeashorterlink.comOpen ↗

Is this spam?
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