Did the bicycle shop fit the bike to you? All of your problems sound like they could be fit issues. Assuming you purchased the bike from a LBS that knows how to do a proper fit, your best bet might be to take the bike back to the shop and tell them what problems you are having. All of these should be correctable. My guesses as to what is going on are the following:
1. This could be a problem with the position of the saddle. Most women prefer the saddle to be level or with the nose very slightly downward. The other problem might be that you are sitting too far forward on the saddle. Your sit bones should be on the widest portion of the saddle. If not, move the saddle forward slightly.
2. Knee pain could be due to the saddle being too low or to the cleats being positioned incorrectly (assuming you have clipless pedals - if you have platform pedals, then this would not apply). A good starting point for pedal position would be that you are able to just reach the pedal with the heel when the pedal is in the downward most position. Be sure to check both sides (while someone holds up the bike) to be sure that both heels can touch the pedal without rocking back and forth. This is the starting point. If you have small feet, you might need to lower the saddle slightly from this position. If you have larger than average feet for your height, you might need to raise the saddle slightly. If you were not having problems with your old bike, measure the distance between the saddle and the lowest position of the pedal, and match that to your new bike.
Another possibile cause for knee pain is that you were trying to push too big a gear. If your pedal cadence was lower than 80 rpm, try using an easier gear. The third cause is that you tried to increase the amount you rode too quickly. I doubt that is the cause, since the pain occurred on your first ride, but if the pain did not start until late in the ride, and you rode more than you have been riding, it is a possibility.
3. This pain is probably because you are holding your head up while you are in a low position. Possible solutions are raising the bar, replacing the stem with a shorter one, or rotating the bar so that the hoods are higher.
4. Wrist ache could be another sign that that you are putting too much weight on your arms, which could also be caused by the bar being too low in relationship to the saddle or the bar is too far from the saddle. Assuming the saddle is not too high, (and based on problem 2, I doubt that it is) the same fixes suggested for problem 3 would apply. The other possibility is that you are just nervous riding a new bike for the first time and are griping the bar too tightly and have your arms locked.
All of these are just guesses on my part. Without seeing you on the bike, I cannot know for sure. That is why a professional fit is important. If the shop where you purchased the bike does not have anyone who can do a proper fit, then it would be worth it to find another shop, and pay them for a fitting. There is nothing worse than having a nice bike and not being able to enjoy it because it does not fit properly.