Fatigue and Sleep Medication

Tom Burns said:

Is it possible that prolonged use of a sleep agent, such as Imovane, can cause one to become
extremely tired?

I'm not referring to next day drowsiness, but sporadic days of extreme fatigue like symptoms.
Something in the order of about one day per week, after 2-3 weeks of nightly use.

I discontinued the medication after pretty much dealing with a medical crisis, and I felt better
the very next day.

Could this have been the cause?

Thank you.

nlm.nih.gov500133.htmlOpen ↗ (kidney and liver disease are also
mentioned there along with breathing problems)

support4hope.commed index 23.htmOpen ↗ Imovane/Zopiclone Contraindications (means "do not take
if you have"😉 Patients with known hypersensitivity to the drug; myasthenia gravis; severe impairment
of respiratory function; acute cerebrovascular accident.[]

So what is impaired respiratory function? apnea, lung diseases (that is why I want my brother off
the @%!! stuff, because it's probably making his apnea worse than it need be). I know his doctor
wants him off it, but I don't know why.

What else can affect breathing (respiratory)? low iron and various anemias.

familydoctor.orgx2682.xmlOpen ↗ Paleness Feeling tired Unusual shortness of breath
*there's of a list of iron-rich foods there*

So where are you on the bloodwork we were discussing a few weeks ago? If you have the results,
please get back up to the other thread, so David Rind can be reminded of the situation. If you don't
have the results, why or when? J

J said:

Tom Burns said:

Is it possible that prolonged use of a sleep agent, such as Imovane, can cause one to become
extremely tired?

Yes. You see melatonin is the natural narcotic, the natural sleep inducer. It participates in the
cycling of the cells. Artificial sleep inducers do not. The fatigue comes from not continuing the
natural cycle.

J said:

So where are you on the bloodwork we were discussing a few weeks ago? If you have the results,
please get back up to the other thread, so David Rind can be reminded of the situation. If you
don't have the results, why or when? J

Just had my follow up exam yesterday. Hemaglobin up from 89/90 to 132, Iron at 9. Both levels up
significantly from pre polyp removal. Red blood cells are also larger by 30% from previous.

I'm feeling much better, but am experiencing one day a week or so of fatigue. Maybe I just
overexerted myself in days prior.

Tom Burns said:

J said:

So where are you on the bloodwork we were discussing a few weeks ago? If you have the results,
please get back up to the other thread, so David Rind can be reminded of the situation. If you
don't have the results, why or when? J

Just had my follow up exam yesterday. Hemaglobin up from 89/90 to 132, Iron at 9. Both levels up
significantly from pre polyp removal. Red blood cells are also larger by 30% from previous.

I'm feeling much better, but am experiencing one day a week or so of fatigue. Maybe I just
overexerted myself in days prior.

I don't have any useful thoughts on whether the sleep medication is contributing to the fatigue.

The hemogolobin level is approaching normal levels, so presumably this really was just iron
deficiency anemia. I remain concerned by the story as to whether something else could have been
causing the iron deficiency (such as a problem with absorption that is being overcome by the
supplements), but it sounds more likely that it was just the polyps.

--
David Rind [email hidden]

Tom Burns <[email hidden]> wrote:
: Is it possible that prolonged use of a sleep agent, such as Imovane, can cause one to become
: extremely tired?

Especially if you might have kidney or liver problems (trouble metabolizing a drug) -- or another
condition such as sleep apnea.

What is your Imovane dosage? Obviously a high dose could make you stay sleepy.

What time are you taking it and then trying to waken?

Sleep aids also worsen daytime sleepiness in those with sleep apnea. many people don't know they
are walking around with sleep apnea. They complain of restless sleep, take sleeping pills and
feel worse.

The main complaint among those with sleep apnea is "excessive daytime sleepiness."

If you have sleeping problems, get a sleep clinic study to find out WHY. Knowing the root causation
of health complaints is always important.

Emma BSN 2004

J <[email hidden]> wrote:

<snip>

: So what is impaired respiratory function? apnea, lung diseases (that is why I want my brother off
: the @%!! stuff, because it's probably making his apnea worse than it need be).

Yep. As my reply mentions, sleeping meds and apnea -- bad news.

Research suggests a link between hypertension and apnea too. (Which makes sense.)

Cheers,

Emma

Emma Chase VanCott said:

J <[email hidden]> wrote:

<snip>

: So what is impaired respiratory function? apnea, lung diseases (that is why I want my brother
: off the @%!! stuff, because it's probably making his apnea worse than it need be).

Yep. As my reply mentions, sleeping meds and apnea -- bad news.

Research suggests a link between hypertension and apnea too. (Which makes sense.)

Cheers,

Emma

Thanks for both of your comments. I feel much better having stopped the sleep meds. I discused
apnea, etc. with my doctor, but I don't think it was the problem. The problem I believe was that I
wasn't getting a good deep sleep withe the meds. I was tired during the day, and after 5 or 6 days
like this I needed a good full daytime sleep without medication. Now without the meds it seems to
be normal.

David Rind said:

I don't have any useful thoughts on whether the sleep medication is contributing to the fatigue.

The hemogolobin level is approaching normal levels, so presumably this really was just iron
deficiency anemia. I remain concerned by the story as to whether something else could have been
causing the iron deficiency (such as a problem with absorption that is being overcome by the
supplements), but it sounds more likely that it was just the polyps.

FYI - Although it is just anecdotal, I'm feeling much much better after discountinuing the sleep
medication. My perception is that the quality of sleep I'm getting now is far better than it was. I
don't wake up feeling tired (given I've had enough hours). I really believe that I was never
achieving REM state under the meds. I also recall dreaming, which I never did with the pills.