When a spoke loosens again, it invites a comparison of nipple condition, tension balance, crossing contact, rim damage and service history. Dealing with a single spoke that refuses to stay tight often points to a deeper issue than just a simple turn of the wrench. If the nipple is slipping or the rim bed is compromised, simple tensioning is rarely a permanent fix.
I have come to appreciate that spoke tension balance matters more than catalogue weight figures. In many cases, factory wheelsets with very low spoke counts can be a false economy for everyday road riding, especially for heavier riders who might benefit from a custom 24 or 28 spoke build for better power transfer and durability.
At what point do you decide that a recurring loose spoke indicates the rim is structurally damaged rather than just needing a better tension balance? Also, how much does the specific crossing contact of the spokes influence your decision to replace a wheel entirely?