amph said:One thing I wanted to add, I was using frequently Ibuprofen. Never more then
800mg and usually maximally 400 a day. Over a longer period (months) say
200- 300 mg per day.
Ibuprofen and other NSAIDs (non steroidal anti-inflammatory drugs, like
aspirin, naproxen, diclofenac, sulindac, ketoprofen, celebrex, vioxx,
etc.) do have the potential to raise BP in some people. I've seen some
people completely unaffected, others very strongly affected.
I always ask for easy but less appreciated contributions to high BP when
I first see a hypertensive patient, simple things like alcohol (raises
BP in some), cough/cold decongestants (sudafed and the like really crank
up the BP), NSAIDs, as examples.
Just had a new young woman patient last week with high blood pressure
and headache. She thought it was sinus head pain, so she took sudafed
decongestant and ibuprofen. I suspected it was the meds causing the
high BP which in turn caused the headache (I explored other
possibilities before coming to this conclusion). So we stopped the
sudafed and switched any pain reliever like ibuprofen to tylenol. Her
BP magically came down to normal and her headache went away. Addition
by subtraction!
Anyway, yes, some people are sensitive to NSAIDs and have BP go up on
them. Others are fine. There are plenty of good reasons to avoid
NSAIDs (and medicines in general) besides this one, but they are good
painkillers, so the balance of benefit and harm is worth talking over
with your doctor if you are concerned.
-- Josh Steinberg MD, Syracuse