General fitness, health and nutrition · Public discussion

Association / ferritin / lipids / C-reactive protein

Started by Doe · · Last activity · 4 posts · 486 views

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General fitness, health and nutrition
Published
10 April 2004
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13 April 2004
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Doe
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  1. Am J Cardiol. 2004 Mar 1;93(5):559-62.

    Association of ferritin and lipids with C-reactive protein.

    Mainous AG 3rd, Wells BJ, Everett CJ, Gill JM, King DE.

    Department of Family Medicine, Medical University of South
    Carolina, Charleston, South Carolina 29425, USA.
    [email hidden]

    C-reactive protein (CRP) and lipids (e.g., low-density
    lipoprotein [LDL]) are both markers of cardiovascular
    disease risk, yet they are not highly correlated. Oxidative
    stress of lipids induced by iron may play a role in vascular
    inflammation, as indicated by CRP. The purpose of this study
    was to examine, in a representative sample of United States
    adults, the relation between ferritin, lipids, and CRP. We
    analyzed data on adults (aged > or =25 years) in the
    National Health and Nutrition Examination Survey III, a
    national public-use data set collected between 1988 and
    1994. Ferritin, total cholesterol, LDL, high-density
    lipoprotein, and ferritin-lipid combinations were analyzed
    in relation to CRP in age-, gender-, and race-adjusted
    models as well as models with other potential confounding
    variables. In adjusted models, neither elevated ferritin
    (odds ratio [OR] 1.11, 95% confidence interval [CI] .94 to
    1.32) nor elevated LDL was significantly associated with
    elevated CRP (OR 1.03, 95% CI 0.79 to 1.33). Patients with
    elevated ferritin and elevated LDL were more likely to have
    elevated CRP (OR 1.68; 95% CI 1.06 to 2.68). Patients with
    elevated ferritin and low high-density lipoprotein were also
    more likely to have elevated CRP (OR 1.71; 95% CI 1.28 to
    2.27). These results suggest that both iron and lipids
    induce inflammation. Future research needs to focus on
    preventive medicine to decrease iron in patients with
    elevated lipids.

    PMID: 14996579 [PubMed - in process]

    ------------------------------------------------------------
    ---------------

    Who loves ya. Tom Jesus Was A Vegetarian!
    jesuswasavegetarian.7h.comjesuswasavegetarian.7h.com Man Is A Herbivore!
    pages.ivillage.commanisaherbivore DEAD
    PEOPLE WALKING
    pages.ivillage.comdeadpeoplewalking

  2. And what exactly are we to make of this, how does it relate
    to any body of theory, to what practical use is it, and
    toward what goal can it be applied? Without this information
    it is but another random abstract plucked from the web, one
    among thousands of such.

  3. Quoted message said:

    Subject: Re: Association / ferritin / lipids / C-reactive protein

    Am J Cardiol. 2004 Mar 1;93(5):559-62.

    Association of ferritin and lipids with C-reactive protein.

    Mainous AG 3rd, Wells BJ, Everett CJ, Gill JM, King DE.

    Department of Family Medicine, Medical University of South
    Carolina, Charleston, South Carolina 29425, USA.
    [email hidden]

    C-reactive protein (CRP) and lipids (e.g., low-density
    lipoprotein [LDL]) are both markers of cardiovascular
    disease risk, yet they are not highly correlated. Oxidative
    stress of lipids induced by iron may play a role in vascular
    inflammation, as indicated by CRP. The purpose of this study
    was to examine, in a representative sample of United States
    adults, the relation between ferritin, lipids, and CRP. We
    analyzed data on adults (aged > or =25 years) in the
    National Health and Nutrition Examination Survey III, a
    national public-use data set collected between 1988 and
    1994. Ferritin, total cholesterol, LDL, high-density
    lipoprotein, and ferritin-lipid combinations were analyzed
    in relation to CRP in age-, gender-, and race-adjusted
    models as well as models with other potential confounding
    variables. In adjusted models, neither elevated ferritin
    (odds ratio [OR] 1.11, 95% confidence interval [CI] .94 to
    1.32) nor elevated LDL was significantly associated with
    elevated CRP (OR 1.03, 95% CI 0.79 to 1.33). Patients with
    elevated ferritin and elevated LDL were more likely to have
    elevated CRP (OR 1.68; 95% CI 1.06 to 2.68). Patients with
    elevated ferritin and low high-density lipoprotein were also
    more likely to have elevated CRP (OR 1.71; 95% CI 1.28 to
    2.27). These results suggest that both iron and lipids
    induce inflammation. Future research needs to focus on
    preventive medicine to decrease iron in patients with
    elevated lipids.

    PMID: 14996579 [PubMed - in process]

    ------------------------------------------------------------
    ---------------

    Who loves ya. Tom Jesus Was A Vegetarian!
    jesuswasavegetarian.7h.comjesuswasavegetarian.7h.com Man Is A Herbivore!
    pages.ivillage.commanisaherbivore DEAD
    PEOPLE WALKING
    pages.ivillage.comdeadpeoplewalking

  4. In india iron stores are low, iron anemia is widespread,
    because the majority diet is veggie alone. The exact
    same region has the world's highest rate of diabetes,
    heart disease, and other related diseases/disorders.
    What does this tell us about the level of iron and this
    very high rate?

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