Aspirin's Antiplatelet Effect

Pat said:

I have read some alarming report that Aspirin's
Antiplatelet Effect diminishes over time and may not be at
all effective after years. How many years? Its not well
defined yet but I was wondering if anyone else has read
about this study and is it just Boogie Man stuff, or is
there some real evidence of this?

Heart attacks and strokes happen more often in individuals
with blood that is 'hypercoagulable'. If you follow proper
nutrition and take nonprescription medication (like
aspirin) to reduce a hypercoagulable state then you can
reduce your risks significantly. This pathway is one of
several to consider.

Specifically, 30 mg is probably all that is needed to block
clotting receptors on the platelet. The clotting receptors,
to my knowledge, do not change with time and the effect of
asprin's effect on them do not change either. However, I am
really interested in your study. Can you give me the link?

--
Winning against heart attack and stroke
sonoscore.comsonoscore.comOpen ↗

Pat said:

I have read some alarming report that Aspirin's
Antiplatelet Effect diminishes over time and may not be at
all effective after years. How many years?

Biochemically, there would not be a reason for this.

Quoted message said:

Its not well defined yet but I was wondering if anyone
else has read about this study and is it just Boogie Man
stuff, or is there some real evidence of this?

Speaking from clinical experience, I have not ever either
seen or suspected development of a "tolerance"

Suggested reading:

almaz.comaspirin.htmlOpen ↗

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

**
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What is all this about?
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"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

Pat said:

I have read some alarming report that Aspirin's
Antiplatelet Effect diminishes over time and may not be
at all effective after years. How

many

Quoted message said:

Quoted message said:

years?

I don't want to appear unappreciative about the opinion
expressed here, however, I have encountered a single
negative about aspirin's long-term use. Maybe you folks
could address this one study.

Aspirin May Not Provide Long-Term Heart Benefit For Some

Platelet Response To Aspirin Studied

< March 17, 2004 > -- The effectiveness of aspirin to reduce
platelet clumping, and in turn reduce heart attack risk, may
peak within months, according to a report in the Journal of
the American College of Cardiology.

mercyhealthplans.comhealthheadlineOpen ↗
s/040317.aspx

Thank You,

Pat

"Pat" <[email hidden]> wrote in part:

Quoted message said:

Maybe you folks could address this one study.

Aspirin May Not Provide Long-Term Heart Benefit For Some

Platelet Response To Aspirin Studied

< March 17, 2004 > -- The effectiveness of aspirin to
reduce platelet clumping, and in turn reduce heart attack
risk, may peak within months, according to a report in the
Journal of the American College of Cardiology.

mercyhealthplans.comhealthheadlinOpen ↗
es/040317.aspx

The Pubmed URL for the abstract is at
tinyurl.com3exuaOpen ↗

Vitamin E may counteract the attenuation of aspirin's collagen-
induced anti-platelet effect, assuming it is confirmd:

tinyurl.com2p7j4Open ↗

--
Jim Chinnis Warrenton, Virginia, USA

Pat said:

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]>
wrote in message "]news:[email hidden]...

Quoted message said:

Pat said:

I have read some alarming report that Aspirin's
Antiplatelet Effect diminishes over time and may not
be at all effective after years. How

many

Quoted message said:

Quoted message said:

years?

I don't want to appear unappreciative about the opinion
expressed here, however, I have encountered a single
negative about aspirin's long-term use. Maybe you folks
could address this one study.

Aspirin May Not Provide Long-Term Heart Benefit For Some

Platelet Response To Aspirin Studied

< March 17, 2004 > -- The effectiveness of aspirin to
reduce platelet clumping, and in turn reduce heart attack
risk, may peak within months, according to a report in the
Journal of the American College of Cardiology.

mercyhealthplans.comhealthheadliOpen ↗
nes/040317.aspx

Thank You,

Pat

Less is not zero. Moreover, there is no clinical evidence as
yet that the cardioprotective benefits of aspirin wanes (the
cited reference describes biochemical evidence of less
inhibition of platelet aggregation which is not the whole
story on the protective effects of aspirin).

Fwiw, in my experience, far more people have heart
attacks and strokes when they are not taking aspirin than
when they are.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

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What is all this about?
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Is this spam?
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"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

Pat said:

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]>
wrote in message
"]news:[email hidden]...

Quoted message said:

Fwiw, in my experience, far more people have heart attacks
and strokes

when they

Quoted message said:

are not taking aspirin than when they are.

Thanks for the reply, its what I wanted to hear.

Also, I am in the process of getting a multi-vitamin that
would include a sufficient amount Vitamin E and Folic Acid,
in addition to other Vitamins and Minerals. Currently, I am
only taking 800Mcg of Folic Acid each day, and not a multi
vitamin. Why? Overwhelmed by all the hype about how much?
What kind? Coatings? Formulations? And the cost can be very
high. In addition, I have a problem swallowing large
tablets. Crushing large tablets would make the procedure too
much work to do each day. Therefore, I may have to get my
multi-Vitamin in the form of multiple small tablets.