Moderately Elevated CPK Reading: Meaning?

Howard Sage said:

If a CPK continues to be moderately high (200 or so) after
statins have been discontinued for over a year, what might
be other possible causes of the elevated reading?

One possibility is a mitochondrial problem (ie MERRF,
MELAS, KS etc).

Quoted message said:

Is a referral to see a rheumatologist in order?

If a mitochondrial problem is being considered, a
neurologist specializing in neuromuscular disorders should
be consulted.

Quoted message said:

Thank you in advance.

You are welcome, Howard.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
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My husband is disabled from the adverse effects of 4 years
of Lipitor 10mg.

For the first 1 full year after discontinuing the
statin, his CPK continued to climb 1,000% before finally
leveling off.

"Howard Sage" <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

If a CPK continues to be moderately high (200 or so) after
statins have been discontinued for over a year, what might
be other possible causes of the elevated reading?

Is a referral to see a rheumatologist in order?

Thank you in advance.

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

Howard Sage said:

If a CPK continues to be moderately high (200 or so)
after statins have been discontinued for over a year,
what might be other possible causes of the elevated
reading?

One possibility is a mitochondrial problem (ie MERRF,
MELAS, KS etc).

Quoted message said:

The other possibility is statin damage. There are many
mitochondrial experts who have become quite interested in
statins, due to all the patients that are finding their way
to them. Many of the mitochondrial damages seen commonly in
statin patients are, under circumstances of normal
congenital causes, only seen by pediatricians - never by
doctors treating adults. Which, perhaps, is one reason so
few doctors recognize statin damage early enough to prevent
disabling damage.

Quoted message said:

Quoted message said:

Is a referral to see a rheumatologist in order?

If a mitochondrial problem is being considered, a
neurologist specializing in neuromuscular disorders should
be consulted.

A rheumatologist may also be in order (but the
neuromuscular specialist would be the first stop). The high
CPK, if associated with mitochondrial damage from the
statins, can be indicative of myopathy. If you exert
yourself beyond the ~20 minutes of ATP stored in the cell,
the mitochondrial damage will prevent the oxygen exchange
that would normally replenish the muscle cell with energy.
The next step is cellular damage, and even cellular death -
apoptosis. The body's reaction to apoptosis is to produce a
great deal of uric acid, which halts the cell death, but
then the crystals form and gout develops. Gout, or
inflammation in the joints, is a form of arthritis, which
is what rheumatologists address.

Be very cautious. When the exertion continues, after
developing gout, people with statin can damage develop
kidney and liver damage and often need gall bladder surgery.
Continuing beyond that can result in rhabdomyolysis, which
can be life threatening

From our experience, this danger exists even in the 3rd year
after discontinuing the statins.

You may need to visit several doctors and bring information
on statin adverse effects along with you. Too many are
unfamiliar with the syndrome, and they tend to deny all
possibility, thus making themselves incapable of treating
the true cause of the problem.

Quoted message said:

Quoted message said:

Thank you in advance.

You are welcome, Howard.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

** Who is the humblest person in the universe?
makeashorterlink.commakeashorterlink.comOpen ↗

What is all this about?
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Is this spam? makeashorterlink.commakeashorterlink.comOpen ↗

"Sharon Hope" <[email hidden]> wrote in message news:<dZ9yc.67408$3x.27659@attbi_s54>...

Quoted message said:

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]>
wrote in message news:7d6f4004c4289972935f54f54c53d489@ne-
ws.teranews.com...

Quoted message said:

Howard Sage said:

If a CPK continues to be moderately high (200 or so)
after statins have been discontinued for over a year,
what might be other possible causes of the elevated
reading?

One possibility is a mitochondrial problem (ie MERRF,
MELAS, KS etc).

Quoted message said:

The other possibility is statin damage. There are many
mitochondrial experts who have become quite interested in
statins, due to all the patients that are finding their
way to them. Many of the mitochondrial damages seen
commonly in statin patients are, under circumstances of
normal congenital causes, only seen by pediatricians -
never by doctors treating adults. Which, perhaps, is one
reason so few doctors recognize statin damage early enough
to prevent disabling damage.

Quoted message said:

Quoted message said:

Is a referral to see a rheumatologist in order?

If a mitochondrial problem is being considered, a
neurologist specializing in neuromuscular disorders
should be consulted.

A rheumatologist may also be in order (but the
neuromuscular specialist would be the first stop). The
high CPK, if associated with mitochondrial damage from the
statins, can be indicative of myopathy. If you exert
yourself beyond the ~20 minutes of ATP stored in the cell,
the mitochondrial damage will prevent the oxygen exchange
that would normally replenish the muscle cell with energy.
The next step is cellular damage, and even cellular death
- apoptosis. The body's reaction to apoptosis is to
produce a great deal of uric acid, which halts the cell
death, but then the crystals form and gout develops. Gout,
or inflammation in the joints, is a form of arthritis,
which is what rheumatologists address.

Be very cautious. When the exertion continues, after
developing gout, people with statin can damage develop
kidney and liver damage and often need gall bladder
surgery. Continuing beyond that can result in
rhabdomyolysis, which can be life threatening

From our experience, this danger exists even in the 3rd
year after discontinuing the statins.

You may need to visit several doctors and bring
information on statin adverse effects along with you. Too
many are unfamiliar with the syndrome, and they tend to
deny all possibility, thus making themselves incapable of
treating the true cause of the problem.

Sharon

Is your husband's CPK still elevated? Urate elevated now?

Was fluid aspirated from the gouty areas? What type of
crystal was found? Was it uric acid or calcium? Did he have
the tests for peripheral neuropathy within the past year and
test positive? Did he have the muscle biopsy and show ragged
red fibres? Has he taken any supplements for the statin
syndrome? what are they and what has helped?

Zee