General fitness, health and nutrition · Public discussion

Insomnia with Lipitor

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General fitness, health and nutrition
Published
13 June 2004
Last activity
19 June 2004
Original author
Tom R
Posts
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  1. I started taking 10 mg of Lipitor in the mornings over 3
    weeks ago. Since starting I have had moderate to severe
    insomnia usually getting only 2 - 3 hours of sleep. Does the
    insomnia subside after a period of time (weeks, months)? Is
    insomnia a side effect of Lipitor or is it a side effect of
    statins in general? Is there another statin that may have
    less an effect on sleep?

    I would appreciate comments from anyone experienced with
    this side effect.

    Tom R.

  2. Hi Tom I have been taking 40mg of lipitor every day for the past 4 months.
    I was advised to take it at night time. It hasn't stopped me sleeping since
    I started it. Maybe others have experience of it
    Gill
    "Tom R" <[email hidden]> wrote in message
    "]news:[email hidden]...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over 3
    weeks ago. Since starting I have had moderate to severe
    insomnia usually getting only 2 - 3 hours of sleep. Does
    the insomnia subside after a period of time (weeks,
    months)? Is insomnia a side effect of Lipitor or is it a
    side effect of statins in general? Is there another statin
    that may have less an effect


    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced with
    this side effect.

    Tom R.

  3. Hi Tom ... I have been taking 20 mg of lipitor for over 6
    years now ... I also take mine in the morning. I read
    somewhere that with lipitor it did not make a difference if
    it was taken in the morning or night. Getting to your
    question though, I did not have any sleep problems that were
    noticeable though. I normally sleep about 6 1/2 hours a day.
    Maybe a quick trip to the doctor about this? Good luck ...

    doug

    --
    -d. best- Exercise Your Mind, Body
    & Freedoms "Tom R"
    <[email hidden]> wrote in message
    s:0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over 3
    weeks ago. Since starting I have had moderate to severe
    insomnia usually getting only 2 - 3 hours of sleep. Does
    the insomnia subside after a period of time (weeks,
    months)? Is insomnia a side effect of Lipitor or is it a
    side effect of statins in general? Is there another statin
    that may have less an effect


    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced with
    this side effect.

    Tom R.

  4. hi Tom , I was taking 40 mg Lipitor in the morning but was actually getting
    around like a zombie when I went off them it was like a weight off my head
    take care Balsey
    "Tom R" <[email hidden]> wrote in message
    "]news:[email hidden]...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over 3
    weeks ago. Since starting I have had moderate to severe
    insomnia usually getting only 2 - 3 hours of sleep. Does
    the insomnia subside after a period of time (weeks,
    months)? Is insomnia a side effect of Lipitor or is it a
    side effect of statins in general? Is there another statin
    that may have less an effect


    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced with
    this side effect.

    Tom R.

  5. "Tom R" <[email hidden]> wrote in message news:<[email hidden]>...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over 3
    weeks ago. Since starting I have had moderate to severe
    insomnia usually getting only 2 - 3 hours of sleep. Does
    the insomnia subside after a period of time (weeks,
    months)? Is insomnia a side effect of Lipitor or is it a
    side effect of statins in general? Is there another statin
    that may have less an effect on sleep?

    I would appreciate comments from anyone experienced with
    this side effect.

    Tom R.

    Salut Tom

    You may wish to print this out and take it to your doctor.
    But because it is replete with charts and graphs make sure
    you copy out the url too so he/she will be able to go online
    to read them fully. Your doctor will see that statins are
    not recommended for "primary prevention". (You). Also
    acquaint your physician with Dr. Paul Phillips of Scripps
    Mercy San Diego, who is running studies on mitochondrial
    myopathy caused by statins, and the work of Dr. Beatrice
    Golomb, who has a NIH funded study on non-cario endpoints of
    statin use. ZEE

    ti.ubc.caletter48.htm

    "Do statins have a role in primary prevention? Conclusions:
    If cardiovascular serious adverse events are viewed in
    isolation, 71 primary prevention patients with
    cardiovascular risk factors have to be treated with a
    statin for 3 to 5 years to prevent one myocardial
    infarction or stroke.

    This cardiovascular benefit is not reflected in 2 measures
    of overall health impact, total mortality and total
    serious adverse events. Therefore, statins have not been
    shown to provide an overall health benefit in primary
    prevention trials."

    The Therapeutics Initiative presents critically appraised
    summary evidence primarily from controlled drug trials. Such
    evidence applies to patients similar to those involved in
    the trails, and may not be generalizable to every patient.
    We are committed to evaluate the effectiveness of our
    educational activities using the Pharmacare/PharmaNet
    databases without identifying individual physicians,
    pharmacies or patients. The Therapeutics Initiative is
    funded by the BC Ministry of Health through a 5-year grant
    to the University of BC. The Therapeutics Initiative
    provides evidence based advice about drug therapy, and is
    not responsible for formulating or adjudicating provincial
    drug policies.

    This is a board where people experiencing statin side
    effects share information. All statin side effects:
    rxlist.comlipitor.pl

    Some on sleeplessness. There will be more if you search.
    rxlist.comlipitor.pl

    A recent story on statin induced memory loss: cb-cb-
    snews.com/stories/2004/05/24/eveningnews/main619351.shtml

    There seem to be people who can take statins without side
    effects. If you aren't one go over this information
    carefully with your doctor. Go over it carefully anyway.

    As everyone here can attest, I have more info if you need
    it.

    Zee

  6. "Tom R" <[email hidden]> wrote in message news:<[email hidden]>...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over 3
    weeks ago. Since starting I have had moderate to severe
    insomnia usually getting only 2 - 3 hours of sleep. Does
    the insomnia subside after a period of time (weeks,
    months)? Is insomnia a side effect of Lipitor or is it a
    side effect of statins in general? Is there another statin
    that may have less an effect on sleep?

    I would appreciate comments from anyone experienced with
    this side effect.

    Tom R.

    Ooops forgot this. There are hits here on lipitor and
    insomnia. medications.comLipitor

    Zee

  7. Absolutely Lipitor causes severe insomnia in patients
    - Pfizer says so in writing, and it definitely did in
    my husband.

    Pfizer states that INSOMNIA is one of the known
    adverse effects.

    See lipitor.comlipitorDe
    sktop?_nfpb=true&_pageLabel=prescribingInformation

    This is the Pfizer website, with the FDA-approved label
    information. Note that under the

    "Clinical Adverse Experiences" section it states: "The
    following adverse events were reported, regardless of
    causality assessment in patients treated with atorvastatin
    in clinical trials. The events in italics occurred in 2%
    of patients and the events in plain type occurred in <2%
    of patients"

    Under "Nervous System" in ITALICS (indicating 2% of
    patients) it is listed:

    INSOMNIA

    Full list of neurological problems known to be associated
    with Lipitor use in this section (Asthenia (i.e., Weakness;
    lack of energy and strength) is listed in the table prior to
    this section):

    "Nervous System: Insomnia, dizziness, paresthesia,
    somnolence, amnesia, abnormal dreams, libido decreased,
    emotional lability, incoordination, peripheral neuropathy,
    torticollis, facial paralysis, hyperkinesia, depression,
    hypesthesia, hypertonia"

    "Tom R" <[email hidden]> wrote in message news:0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over 3
    weeks ago. Since starting I have had moderate to severe
    insomnia usually getting only 2 - 3 hours of sleep. Does
    the insomnia subside after a period of time (weeks,
    months)? Is insomnia a side effect of Lipitor or is it a
    side effect of statins in general? Is there another statin
    that may have less an effect


    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced with
    this side effect.

    Tom R.

  8. "Tom R" <[email hidden]> wrote in message news:<[email hidden]>...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over 3
    weeks ago. Since starting I have had moderate to severe
    insomnia usually getting only 2 - 3 hours of sleep. Does
    the insomnia subside after a period of time (weeks,
    months)? Is insomnia a side effect of Lipitor or is it a
    side effect of statins in general? Is there another statin
    that may have less an effect on sleep?

    I would appreciate comments from anyone experienced with
    this side effect.

    Tom R.

    Tom here is the sleep disorders board I mentioned. If you
    use your browser "find" function for lipitor, insomnia
    etc you'll find several hits. Prior to taking lipitor I
    had not had insomnia. Since stopping statins I have not
    had insomnia.

    sleephomepage.orgmsgs.html

    Zee

  9. "Gill" <[email hidden]> wrote in message news:<[email hidden]>...

    Quoted message said:

    Hi Tom I have been taking 40mg of lipitor every day for
    the past 4 months. I was advised to take it at night time.
    It hasn't stopped me sleeping since I started it. Maybe
    others have experience of it Gill "Tom R"
    <[email hidden]> wrote in message news:0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over 3
    weeks ago. Since starting I have had moderate to severe
    insomnia usually getting only 2 - 3 hours of sleep. Does
    the insomnia subside after a period of time (weeks,
    months)? Is insomnia a side effect of Lipitor or is it a
    side effect of statins in general? Is there another
    statin that may have less an effect


    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced with
    this side effect.

    Tom R.

    I took lipitor for over a year and suffered terrible
    insommnia, which mitigated immediately: the first day I
    didn't take it, I slept five hours without waking. It was
    unbelievable, and answered my question about it. Everytime I
    started taking Lipitor again (I was told I had to) I would
    be sleepless. I stuck with it. I began experiencing terrible
    leg pain. My exercise physiologist said there is a hormone
    excreted (Andrew?) during sleep that repairs minor muscle
    tears from everyday living and when you don't sleep it
    isn't. Coupled with other cogntive adverse effect which I
    experienced from lipitor (for I think this was to do with a
    gland in the brain) I finally stopped taking Lipitor. I took
    Baycol, then. And that's another story.

    Most of the people I know who took Lipitor and had adverse
    effects had insommnia, and I know there is at least *one*
    university sleep lab that has a website chat board where you
    can find people discussing their Lipitor insommnia. I'm
    still searching for it. Will post when I find it.

    Zee

  10. It seems to me I heard somewhere that Gill wrote in article
    <[email hidden]>:

    Quoted message said:

    Hi Tom I have been taking 40mg of lipitor every day for the
    past 4 months. I was advised to take it at night time. It
    hasn't stopped me sleeping since I started it. Maybe others
    have experience of it

    And I've been on Lipitor for six years, currently at 80mg
    taken with evening meal--I was told the body produces
    relatively more cholesterol over night, so that's when the
    statins are most effective. Nothing stops me from sleeping,
    though I need less sleep now than when I was younger. One of
    the (dis?) advantages of aging.

    I can't recall every hearing of sleeplessness in relation
    to statins.

    Quoted message said:

    "Tom R" <[email hidden]> wrote in message news:0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over 3
    weeks ago. Since starting I have had moderate to severe
    insomnia usually getting only 2 - 3 hours of sleep. Does
    the insomnia subside after a period of time (weeks,
    months)? Is insomnia a side effect of Lipitor or is it a
    side effect of statins in general? Is there another
    statin that may have less an effect


    on

    Quoted message said:

    sleep?

    Is there any reason to believe your mind might be active and
    keeping you awake from concern about your health? Even if
    not, it might be helpful for you and your doctor to have a
    heart to heart conversation.
    --
    Don [email hidden]

  11. I spoke w/ my Dr over the phone about this problem. He
    suggested that I cut back to 5 mg to see what happens. He
    also said that he would try me on other statins if I wanted.
    I just wanted to avoid months of trial and error if I could.

    Tom R.

    "D. Best" <Exercise Your Body, Mind & Freedoms@Nam 69,70,71>
    wrote in message "]news:[email hidden]...

    Quoted message said:

    Hi Tom ... I have been taking 20 mg of lipitor for over
    6 years now ... I also take mine in the morning. I read
    somewhere that with lipitor it did not make a
    difference if it was taken in the morning or night.
    Getting to your question though, I did not have any
    sleep problems that were


    noticeable

    Quoted message said:

    though. I normally sleep about 6 1/2 hours a day. Maybe a
    quick trip to the doctor about this? Good luck ...

    doug

    --
    -d. best- Exercise Your Mind,
    Body & Freedoms "Tom R"
    <[email hidden]> wrote in
    message0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over 3
    weeks ago.


    Since

    Quoted message said:
    Quoted message said:

    starting I have had moderate to severe insomnia usually
    getting only 2 -


    3

    Quoted message said:
    Quoted message said:

    hours of sleep. Does the insomnia subside after a period
    of time (weeks, months)? Is insomnia a side effect of
    Lipitor or is it a side effect of statins in general? Is
    there another statin that may have less an effect


    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced with
    this side


    effect.

    Quoted message said:
    Quoted message said:


    Tom R.


  12. "Sharon Hope" <[email hidden]> wrote in message
    news:r6ayc.25660$HG.7786@attbi_s53...

    Quoted message said:

    Absolutely Lipitor causes severe insomnia in patients -
    Pfizer says so in writing, and it definitely did in my
    husband.

    Pfizer states that INSOMNIA is one of the known adverse
    effects.

    Sharon that's an outright lie. They say that insomnia was
    noted in greater than 2% of the population studied. They say
    nothing about about it being a known adverse effect. They
    say nothing about Lipitor causing "severe insomnia" Only
    that it occurred in greater than 2% of the study population.
    My guess is that insomnia occurs in greater than 2% of the
    general population. So this proves nothing.

    Bill

    Quoted message said:


    See


    lipitor.comlipitorDeskto
    p?_nfpb=true&_pageLabel=prescribingInformation

    Quoted message said:


    This is the Pfizer website, with the FDA-approved label
    information. Note that under the

    "Clinical Adverse Experiences" section it states: "The
    following adverse events were reported, regardless of
    causality assessment in patients treated with atorvastatin
    in clinical trials. The events in italics occurred in 2%
    of patients and the events in plain type occurred in <2%
    of patients"

    Under "Nervous System" in ITALICS (indicating 2% of
    patients) it is listed:

    INSOMNIA

    Full list of neurological problems known to be associated
    with Lipitor use in this section (Asthenia (i.e.,
    Weakness; lack of energy and strength) is listed in the
    table prior to this section):

    "Nervous System: Insomnia, dizziness, paresthesia,
    somnolence, amnesia, abnormal dreams, libido decreased,
    emotional lability, incoordination, peripheral neuropathy,
    torticollis, facial paralysis, hyperkinesia, depression,
    hypesthesia, hypertonia"

    "Tom R" <[email hidden]> wrote in message news:0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over 3
    weeks ago. Since starting I have had moderate to severe
    insomnia usually getting only 2 - 3 hours of sleep. Does
    the insomnia subside after a period of time (weeks,
    months)? Is insomnia a side effect of Lipitor or is it a
    side effect of statins in general? Is there another
    statin that may have less an effect


    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced with
    this side effect.

    Tom R.

  13. Thanks for the info. Would like to follow-up with that link
    if you find it.

    "Zee" <[email hidden]> wrote in message
    "]news:[email hidden]...

    Quoted message said:

    "Gill" <[email hidden]> wrote in message


    news:<[email hidden]>...

    Quoted message said:
    Quoted message said:

    Hi Tom I have been taking 40mg of lipitor every day for
    the past 4


    months.

    Quoted message said:
    Quoted message said:

    I was advised to take it at night time. It hasn't
    stopped me sleeping


    since

    Quoted message said:
    Quoted message said:

    I started it. Maybe others have experience of it Gill
    "Tom R" <[email hidden]> wrote in message news:0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over
    3 weeks ago.


    Since

    Quoted message said:
    Quoted message said:
    Quoted message said:

    starting I have had moderate to severe insomnia
    usually getting only


    2 - 3

    Quoted message said:
    Quoted message said:
    Quoted message said:

    hours of sleep. Does the insomnia subside after a
    period of time


    (weeks,

    Quoted message said:
    Quoted message said:
    Quoted message said:

    months)? Is insomnia a side effect of Lipitor or is it
    a side effect


    of

    Quoted message said:
    Quoted message said:
    Quoted message said:

    statins in general? Is there another statin that may
    have less an


    effect

    Quoted message said:
    Quoted message said:

    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced
    with this side


    effect.

    Quoted message said:
    Quoted message said:
    Quoted message said:


    Tom R.

    I took lipitor for over a year and suffered terrible
    insommnia, which mitigated immediately: the first day I
    didn't take it, I slept five hours without waking. It was
    unbelievable, and answered my question about it. Everytime
    I started taking Lipitor again (I was told I had to) I
    would be sleepless. I stuck with it. I began experiencing
    terrible leg pain. My exercise physiologist said there is
    a hormone excreted (Andrew?) during sleep that repairs
    minor muscle tears from everyday living and when you don't
    sleep it isn't. Coupled with other cogntive adverse effect
    which I experienced from lipitor (for I think this was to
    do with a gland in the brain) I finally stopped taking
    Lipitor. I took Baycol, then. And that's another story.

    Most of the people I know who took Lipitor and had adverse
    effects had insommnia, and I know there is at least *one*
    university sleep lab that has a website chat board where
    you can find people discussing their Lipitor insommnia.
    I'm still searching for it. Will post when I find it.

    Zee

  14. My health is fine, so I am not worrying about that. My
    cholesterol is borderline high and with my family history my
    Dr wanted me to try a statin.

    Tom R.

    "Don Kirkman" <[email hidden]> wrote in message
    "]news:[email hidden]...

    Quoted message said:

    It seems to me I heard somewhere that Gill wrote in
    article <[email hidden]>:

    Quoted message said:

    Hi Tom I have been taking 40mg of lipitor every day for
    the past 4


    months.

    Quoted message said:
    Quoted message said:

    I was advised to take it at night time. It hasn't stopped
    me sleeping


    since

    Quoted message said:
    Quoted message said:

    I started it. Maybe others have experience of it

    And I've been on Lipitor for six years, currently at 80mg
    taken with evening meal--I was told the body produces
    relatively more cholesterol over night, so that's when the
    statins are most effective. Nothing stops me from
    sleeping, though I need less sleep now than when I was
    younger. One of the (dis?) advantages of aging.

    I can't recall every hearing of sleeplessness in relation
    to statins.

    Quoted message said:

    "Tom R" <[email hidden]> wrote in message news:0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over
    3 weeks ago.


    Since

    Quoted message said:
    Quoted message said:
    Quoted message said:

    starting I have had moderate to severe insomnia usually
    getting only


    2 - 3

    Quoted message said:
    Quoted message said:
    Quoted message said:

    hours of sleep. Does the insomnia subside after a
    period of time


    (weeks,

    Quoted message said:
    Quoted message said:
    Quoted message said:

    months)? Is insomnia a side effect of Lipitor or is it
    a side effect


    of

    Quoted message said:
    Quoted message said:
    Quoted message said:

    statins in general? Is there another statin that may
    have less an


    effect

    Quoted message said:
    Quoted message said:

    on

    Quoted message said:

    sleep?

    Is there any reason to believe your mind might be active
    and keeping you awake from concern about your health? Even
    if not, it might be helpful for you and your doctor to
    have a heart to heart conversation.
    --
    Don [email hidden]

  15. Did your doctor tell you that Insomnia is listed on the
    Lipitor label? If not, why not?

    "Tom R" <[email hidden]> wrote in message news:0N6yc.1900$Di3.1714@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I spoke w/ my Dr over the phone about this problem. He
    suggested that I


    cut

    Quoted message said:

    back to 5 mg to see what happens. He also said that he
    would try me on


    other

    Quoted message said:

    statins if I wanted. I just wanted to avoid months of
    trial and error if I could.

    Tom R.

    "D. Best" <Exercise Your Body, Mind & Freedoms@Nam
    69,70,71> wrote in message news:qtCdnU71Oa2qUlrdRVn-
    [email hidden]...

    Quoted message said:

    Hi Tom ... I have been taking 20 mg of lipitor for over
    6 years now ...


    I

    Quoted message said:
    Quoted message said:

    also take mine in the morning. I read somewhere that
    with lipitor it


    did

    Quoted message said:
    Quoted message said:

    not make a difference if it was taken in the morning or
    night. Getting


    to

    Quoted message said:
    Quoted message said:

    your question though, I did not have any sleep problems
    that were


    noticeable

    Quoted message said:

    though. I normally sleep about 6 1/2 hours a day. Maybe
    a quick trip


    to

    Quoted message said:
    Quoted message said:

    the doctor about this? Good luck ...

    doug

    --
    -d. best- Exercise Your Mind,
    Body & Freedoms "Tom R"
    <[email hidden]> wrote in
    messageIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over
    3 weeks ago.


    Since

    Quoted message said:
    Quoted message said:

    starting I have had moderate to severe insomnia
    usually getting only


    2 -

    Quoted message said:

    3

    Quoted message said:
    Quoted message said:

    hours of sleep. Does the insomnia subside after a
    period of time


    (weeks,

    Quoted message said:
    Quoted message said:
    Quoted message said:

    months)? Is insomnia a side effect of Lipitor or is it
    a side effect


    of

    Quoted message said:
    Quoted message said:
    Quoted message said:

    statins in general? Is there another statin that may
    have less an


    effect

    Quoted message said:
    Quoted message said:

    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced
    with this side


    effect.

    Quoted message said:
    Quoted message said:


    Tom R.

  16. Quoted message said:

    "Sharon Hope" <[email hidden]> wrote in message
    news:r6ayc.25660$HG.7786@attbi_s53...

    Quoted message said:

    Absolutely Lipitor causes severe insomnia in patients -
    Pfizer says so in writing, and it definitely did in my
    husband.

    Pfizer states that INSOMNIA is one of the known adverse
    effects.

    Sharon that's an outright lie. They say that insomnia was
    noted in greater than 2% of the population studied. They
    say nothing about about it being a known adverse effect.
    They say nothing about Lipitor causing "severe insomnia"
    Only that it occurred in greater than 2% of the study
    population. My guess is that insomnia occurs in greater
    than 2% of the general population. So this proves nothing.

    Bill

    Didn't you mean "less than"? It's states: "The events in
    *italics* occurred in >2% of patients and the events in
    plain type occurred in <2% of patients."

    Insomnia is in italics.

    L

    Quoted message said:
    Quoted message said:

    See


    lipitor.comlipitorDeskt
    op?_nfpb=true&_pageLabel=prescribingInformation

    Quoted message said:


    This is the Pfizer website, with the FDA-approved label
    information. Note that under the

    "Clinical Adverse Experiences" section it states: "The
    following adverse events were reported, regardless of
    causality assessment in patients treated with
    atorvastatin in clinical trials. The events in italics
    occurred in 2% of patients and the events in plain type
    occurred in <2% of patients"

    Under "Nervous System" in ITALICS (indicating 2% of
    patients) it is listed:

    INSOMNIA

    Full list of neurological problems known to be associated
    with Lipitor use in this section (Asthenia (i.e.,
    Weakness; lack of energy and strength) is listed in the
    table prior to this section):

    "Nervous System: Insomnia, dizziness, paresthesia,
    somnolence, amnesia, abnormal dreams, libido decreased,
    emotional lability, incoordination, peripheral
    neuropathy, torticollis, facial paralysis, hyperkinesia,
    depression, hypesthesia, hypertonia"

    "Tom R" <[email hidden]> wrote in message news:0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over
    3 weeks ago. Since starting I have had moderate to
    severe insomnia usually getting only 2 - 3 hours of
    sleep. Does the insomnia subside after a period of time
    (weeks, months)? Is insomnia a side effect of Lipitor
    or is it a side effect of statins in general? Is there
    another statin that may have less an effect


    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced
    with this side effect.

    Tom R.


  17. Lipitor caused severe insomnia in 100% of the statin takers
    in our household.

    As for the lying, read the label - it says "Clinical Adverse
    xperiences" - if it is a lie, it is Pfizer's lie.

    "]news:[email hidden]...

    Quoted message said:


    "Sharon Hope" <[email hidden]> wrote in message
    news:r6ayc.25660$HG.7786@attbi_s53...

    Quoted message said:

    Absolutely Lipitor causes severe insomnia in patients -
    Pfizer says so


    in

    Quoted message said:
    Quoted message said:

    writing, and it definitely did in my husband.

    Pfizer states that INSOMNIA is one of the known adverse
    effects.

    Sharon that's an outright lie. They say that insomnia was
    noted in greater than 2% of the population studied. They
    say nothing about about it being a known adverse effect.
    They say nothing about Lipitor causing "severe insomnia"
    Only that it occurred in greater than 2% of the study


    population.

    Quoted message said:

    My guess is that insomnia occurs in greater than 2% of
    the general


    population.

    Quoted message said:

    So this proves nothing.

    Bill

    Quoted message said:


    See



    lipitor.comlipitorDeskto
    p?_nfpb=true&_pageLabel=prescribingInformation

    Quoted message said:
    Quoted message said:


    This is the Pfizer website, with the FDA-approved label
    information.


    Note

    Quoted message said:
    Quoted message said:

    that under the

    "Clinical Adverse Experiences" section it states: "The
    following adverse events were reported, regardless of
    causality assessment in patients treated with
    atorvastatin in clinical trials. The events in italics
    occurred in 2% of patients and the events in plain


    type

    Quoted message said:
    Quoted message said:

    occurred in <2% of patients"

    Under "Nervous System" in ITALICS (indicating 2% of
    patients) it is


    listed:

    Quoted message said:
    Quoted message said:


    INSOMNIA

    Full list of neurological problems known to be
    associated with Lipitor


    use

    Quoted message said:
    Quoted message said:

    in this section (Asthenia (i.e., Weakness; lack of
    energy and strength)


    is

    Quoted message said:
    Quoted message said:

    listed in the table prior to this section):

    "Nervous System: Insomnia, dizziness, paresthesia,
    somnolence, amnesia, abnormal dreams, libido decreased,
    emotional lability, incoordination, peripheral
    neuropathy, torticollis, facial paralysis, hyperkinesia,
    depression, hypesthesia, hypertonia"

    "Tom R" <[email hidden]> wrote in message news:0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over
    3 weeks ago.


    Since

    Quoted message said:
    Quoted message said:
    Quoted message said:

    starting I have had moderate to severe insomnia
    usually getting only


    2 - 3

    Quoted message said:
    Quoted message said:
    Quoted message said:

    hours of sleep. Does the insomnia subside after a
    period of time


    (weeks,

    Quoted message said:
    Quoted message said:
    Quoted message said:

    months)? Is insomnia a side effect of Lipitor or is it
    a side effect


    of

    Quoted message said:
    Quoted message said:
    Quoted message said:

    statins in general? Is there another statin that may
    have less an


    effect

    Quoted message said:
    Quoted message said:

    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced
    with this side


    effect.

    Quoted message said:
    Quoted message said:
    Quoted message said:


    Tom R.


  18. Per this study, the neuropsychiatric side effects of statins
    were INSOMNIA at 11% (11% > 2%)

    ncbi.nlm.nih.govquery.fcgi
    db=pubmed&dopt=Abstract&list_uids=8146847

    Therapie. 1993 Sep-Oct;48(5):509-12. A one-year prospective
    and intensive pharmacovigilance of antilipemic drugs in an
    hospital consultation for prevention of risk factors]

    [Article in French]

    Jacquet A, Colomes M, Ferrieres J, Denat M, Douste-Blazy P,
    Monstastruc JL.

    Service de Pharmacologie Medicale et Clinique, Centre
    Hospitalier Universitaire, Faculte de Medecine, Toulouse.

    From the abstract:

    "The most frequently observed side effects were gastralgia
    (19.5%) observed with the three classes of drugs and
    hepatitis with HMG-CoA reductase inhibitors (8.5%) or
    fibrates (3%) whereas myopathy (12%) only occurred with
    statines. The other side effects were cutaneous (14%:
    eczema, skin rashes) or neuropsychiatric (11%:
    insomnia...) ones."

    "]news:[email hidden]...

    Quoted message said:


    "Sharon Hope" <[email hidden]> wrote in message
    news:r6ayc.25660$HG.7786@attbi_s53...

    Quoted message said:

    Absolutely Lipitor causes severe insomnia in patients -
    Pfizer says so


    in

    Quoted message said:
    Quoted message said:

    writing, and it definitely did in my husband.

    Pfizer states that INSOMNIA is one of the known adverse
    effects.

    Sharon that's an outright lie. They say that insomnia was
    noted in greater than 2% of the population studied. They
    say nothing about about it being a known adverse effect.
    They say nothing about Lipitor causing "severe insomnia"
    Only that it occurred in greater than 2% of the study


    population.

    Quoted message said:

    My guess is that insomnia occurs in greater than 2% of
    the general


    population.

    Quoted message said:

    So this proves nothing.

    Bill

    Quoted message said:


    See



    lipitor.comlipitorDeskto
    p?_nfpb=true&_pageLabel=prescribingInformation

    Quoted message said:
    Quoted message said:


    This is the Pfizer website, with the FDA-approved label
    information.


    Note

    Quoted message said:
    Quoted message said:

    that under the

    "Clinical Adverse Experiences" section it states: "The
    following adverse events were reported, regardless of
    causality assessment in patients treated with
    atorvastatin in clinical trials. The events in italics
    occurred in 2% of patients and the events in plain


    type

    Quoted message said:
    Quoted message said:

    occurred in <2% of patients"

    Under "Nervous System" in ITALICS (indicating 2% of
    patients) it is


    listed:

    Quoted message said:
    Quoted message said:


    INSOMNIA

    Full list of neurological problems known to be
    associated with Lipitor


    use

    Quoted message said:
    Quoted message said:

    in this section (Asthenia (i.e., Weakness; lack of
    energy and strength)


    is

    Quoted message said:
    Quoted message said:

    listed in the table prior to this section):

    "Nervous System: Insomnia, dizziness, paresthesia,
    somnolence, amnesia, abnormal dreams, libido decreased,
    emotional lability, incoordination, peripheral
    neuropathy, torticollis, facial paralysis, hyperkinesia,
    depression, hypesthesia, hypertonia"

    "Tom R" <[email hidden]> wrote in message news:0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over
    3 weeks ago.


    Since

    Quoted message said:
    Quoted message said:
    Quoted message said:

    starting I have had moderate to severe insomnia
    usually getting only


    2 - 3

    Quoted message said:
    Quoted message said:
    Quoted message said:

    hours of sleep. Does the insomnia subside after a
    period of time


    (weeks,

    Quoted message said:
    Quoted message said:
    Quoted message said:

    months)? Is insomnia a side effect of Lipitor or is it
    a side effect


    of

    Quoted message said:
    Quoted message said:
    Quoted message said:

    statins in general? Is there another statin that may
    have less an


    effect

    Quoted message said:
    Quoted message said:

    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced
    with this side


    effect.

    Quoted message said:
    Quoted message said:
    Quoted message said:


    Tom R.


  19. INSOMNIA and/or Sleep Disorders:

    Pravastatin = 8.7% (8.7% > 2%) Lovastatin = 4.8% (4.8% > 2%)
    Simvastatin = 3.6% (3.6% > 2%)

    AFTER ONLY 6 WEEKS!

    ncbi.nlm.nih.govquery.fcgi
    db=pubmed&dopt=Abstract&list_uids=1904357 Eur J Clin
    Pharmacol. 1991;40 Suppl 1:S27-32. Comparison of different
    HMG-CoA reductase inhibitors.

    Ditschuneit HH, Kuhn K, Ditschuneit H.

    Department of Medicine, University of Ulm, Federal Republic
    of Germany.

    "Three agents, pravastatin (P), lovastatin (L) and
    simvastatin (S), have been studied with reference to long-
    term lipid-lowering effect, tolerance and clinical
    safety....In the S group headache (3.6% of patients),
    abdominal discomfort (2.4%), sleeping disturbances (3.6%),
    and muscle pain (2.4%) were reported. In the L group
    headache (7.1%), abdominal discomfort (4.8%), sleep
    disorders (4.8%), and muscle pain (4.8%) were observed. In
    the P group one patient complained of abdominal discomfort
    (8.7%) and one of sleep disorders
    (8.7%). Increases in CPK were observed in the S group (4.8%
    of patients) and in the L group (11.9%) "

    "]news:[email hidden]...

    Quoted message said:

    ... "Sharon Hope" <[email hidden]> wrote in message
    news:r6ayc.25660$HG.7786@attbi_s53...

    Quoted message said:

    Absolutely Lipitor causes severe insomnia in patients -
    Pfizer says so


    in

    Quoted message said:
    Quoted message said:

    writing, and it definitely did in my husband.

    Pfizer states that INSOMNIA is one of the known adverse
    effects.

    Sharon that's an outright lie. They say that insomnia was
    noted in greater than 2% of the population studied. They
    say nothing about about it being a known adverse effect.
    They say nothing about Lipitor causing "severe insomnia"
    Only that it occurred in greater than 2% of the study


    population.

    Quoted message said:

    My guess is that insomnia occurs in greater than 2% of
    the general


    population.

    Quoted message said:

    So this proves nothing.

    Bill

    Quoted message said:


    See



    lipitor.comlipitorDeskto
    p?_nfpb=true&_pageLabel=prescribingInformation

    Quoted message said:
    Quoted message said:


    This is the Pfizer website, with the FDA-approved label
    information.


    Note

    Quoted message said:
    Quoted message said:

    that under the

    "Clinical Adverse Experiences" section it states: "The
    following adverse events were reported, regardless of
    causality assessment in patients treated with
    atorvastatin in clinical trials. The events in italics
    occurred in 2% of patients and the events in plain


    type

    Quoted message said:
    Quoted message said:

    occurred in <2% of patients"

    Under "Nervous System" in ITALICS (indicating 2% of
    patients) it is


    listed:

    Quoted message said:
    Quoted message said:


    INSOMNIA

    Full list of neurological problems known to be
    associated with Lipitor


    use

    Quoted message said:
    Quoted message said:

    in this section (Asthenia (i.e., Weakness; lack of
    energy and strength)


    is

    Quoted message said:
    Quoted message said:

    listed in the table prior to this section):

    "Nervous System: Insomnia, dizziness, paresthesia,
    somnolence, amnesia, abnormal dreams, libido decreased,
    emotional lability, incoordination, peripheral
    neuropathy, torticollis, facial paralysis, hyperkinesia,
    depression, hypesthesia, hypertonia"

    "Tom R" <[email hidden]> wrote in message news:0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over
    3 weeks ago.


    Since

    Quoted message said:
    Quoted message said:
    Quoted message said:

    starting I have had moderate to severe insomnia
    usually getting only


    2 - 3

    Quoted message said:
    Quoted message said:
    Quoted message said:

    hours of sleep. Does the insomnia subside after a
    period of time


    (weeks,

    Quoted message said:
    Quoted message said:
    Quoted message said:

    months)? Is insomnia a side effect of Lipitor or is it
    a side effect


    of

    Quoted message said:
    Quoted message said:
    Quoted message said:

    statins in general? Is there another statin that may
    have less an


    effect

    Quoted message said:
    Quoted message said:

    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced
    with this side


    effect.

    Quoted message said:
    Quoted message said:
    Quoted message said:


    Tom R.


  20. See also:

    Sleep disturbance and HMG CoA reductase inhibitors.

    Black DM, Lamkin G, Olivera EH, Laskarzewski PM, Stein EA.

    "]news:[email hidden]...

    Quoted message said:


    "Sharon Hope" <[email hidden]> wrote in message
    news:r6ayc.25660$HG.7786@attbi_s53...

    Quoted message said:

    Absolutely Lipitor causes severe insomnia in patients -
    Pfizer says so


    in

    Quoted message said:
    Quoted message said:

    writing, and it definitely did in my husband.

    Pfizer states that INSOMNIA is one of the known adverse
    effects.

    Sharon that's an outright lie. They say that insomnia was
    noted in greater than 2% of the population studied. They
    say nothing about about it being a known adverse effect.
    They say nothing about Lipitor causing "severe insomnia"
    Only that it occurred in greater than 2% of the study


    population.

    Quoted message said:

    My guess is that insomnia occurs in greater than 2% of
    the general


    population.

    Quoted message said:

    So this proves nothing.

    Bill

    Quoted message said:


    See



    lipitor.comlipitorDeskto
    p?_nfpb=true&_pageLabel=prescribingInformation

    Quoted message said:
    Quoted message said:


    This is the Pfizer website, with the FDA-approved label
    information.


    Note

    Quoted message said:
    Quoted message said:

    that under the

    "Clinical Adverse Experiences" section it states: "The
    following adverse events were reported, regardless of
    causality assessment in patients treated with
    atorvastatin in clinical trials. The events in italics
    occurred in 2% of patients and the events in plain


    type

    Quoted message said:
    Quoted message said:

    occurred in <2% of patients"

    Under "Nervous System" in ITALICS (indicating 2% of
    patients) it is


    listed:

    Quoted message said:
    Quoted message said:


    INSOMNIA

    Full list of neurological problems known to be
    associated with Lipitor


    use

    Quoted message said:
    Quoted message said:

    in this section (Asthenia (i.e., Weakness; lack of
    energy and strength)


    is

    Quoted message said:
    Quoted message said:

    listed in the table prior to this section):

    "Nervous System: Insomnia, dizziness, paresthesia,
    somnolence, amnesia, abnormal dreams, libido decreased,
    emotional lability, incoordination, peripheral
    neuropathy, torticollis, facial paralysis, hyperkinesia,
    depression, hypesthesia, hypertonia"

    "Tom R" <[email hidden]> wrote in message news:0zIxc.52550$_k3.1315577@bgtnsc05-
    news.ops.worldnet.att.net...

    Quoted message said:

    I started taking 10 mg of Lipitor in the mornings over
    3 weeks ago.


    Since

    Quoted message said:
    Quoted message said:
    Quoted message said:

    starting I have had moderate to severe insomnia
    usually getting only


    2 - 3

    Quoted message said:
    Quoted message said:
    Quoted message said:

    hours of sleep. Does the insomnia subside after a
    period of time


    (weeks,

    Quoted message said:
    Quoted message said:
    Quoted message said:

    months)? Is insomnia a side effect of Lipitor or is it
    a side effect


    of

    Quoted message said:
    Quoted message said:
    Quoted message said:

    statins in general? Is there another statin that may
    have less an


    effect

    Quoted message said:
    Quoted message said:

    on

    Quoted message said:

    sleep?

    I would appreciate comments from anyone experienced
    with this side


    effect.

    Quoted message said:
    Quoted message said:
    Quoted message said:


    Tom R.


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