Risk Factors Website

Brad Sheppard said:

I may be creating a CAD risk factors website since I can't
find in one source ALL risk factors and their details.

It seems you are not looking hard enough.

Quoted message said:

EG - Hba1c predicts CAD better than Chol.

Elevated HgbA1C (ie diabetes) is risk equivalent rather than
a risk factor.

Quoted message said:

Also, sensitivy of BP to salt predicts CAD.

Hypertension us a risk factor for CAD.

Quoted message said:

A biggie - abstaining from alcohol is a big risk factor.

Not really. There are folks who have higher CAD risk from
drinking alcohol.

Quoted message said:

The details I include would be links to the original
research or websites.

It seems you have difficulties interpreting the information
correctly.

Quoted message said:

What is your ranking of risk factors in terms of
predictive power?

(1) Cigarette smoking.
(2) Family history
(3) Metabolic syndrome (MetS)
(4) Hypertension
(5) Dyslipidemia
(6) Age over 35 yo
(7) Male gender

Elevated HgbA1C (ie diabetes) is not a risk factor but a
risk equivalent.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

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[email hidden] (Brad Sheppard) wrote in message news:<[email hidden]>...

Quoted message said:

I may be creating a CAD risk factors website since I can't
find in one source ALL risk factors and their details. EG
- Hba1c predicts CAD better than Chol. Also, sensitivy of
BP to salt predicts CAD. A biggie - abstaining from
alcohol is a big risk factor. The details I include would
be links to the original research or websites. What is
your ranking of risk factors in terms of predictive power?

This sounds like a great idea Brad. My entry for most
important risk factor would be low hdl. This week.

Next week? Who knows.

According to the latest research, CRP and homocysteine are
no longer favoured front-runners, and I heard a rumour last
week that HDL is set for a fall.

As for high cholesterol as an independent risk factor, here
are my numbers, with no heart disease: Total cholesterol 9.4-
12.59, ldl
7.28-11.31.

I think it would be great too if you included this. Heh. (I
was just hoping for an excuse to post it here. We could use
a little levity on this board. Hope you don't mind.)

etch-a-sketch.comonlineetch.htmOpen ↗

Zee

To clarify:

for men, Hba1c predicts mortality and CAD better than chol,
even for non-diabetics. See
vanderbiltowc.wellsource.comcontent.aspOpen ↗
and for the journal article, see
bmj.bmjjournals.com15Open ↗

Re:sensitivy of BP to salt predicts CAD - I should have
added "even for people with normal BP." Didn't know that,
did you Chung?

Re: abstainance from alcohol as a risk factor add - versus
moderate drinking. Beyond moderate drinking increases risk.
"But far more Americans drink less, not more, than would be
most healthful for them. To fail to inform these patients
about the benefits of moderate drinking is both
counterproductive and dishonest. Physicians may ask, "How
much alcohol do you drink," "Is there any reason that you
don't drink (or that you drink so little)," and (to those
without religious objections, previous drinking problems,
etc.), "Do you know that one or two glasses of wine or beer
a day can be good for your health if you can safely consume
them?"
acsh.orgpcyes.htmlOpen ↗

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote
in message news:<[email hidden]>...

Quoted message said:

Brad Sheppard said:

I may be creating a CAD risk factors website since I
can't find in one source ALL risk factors and their
details.

It seems you are not looking hard enough.

Quoted message said:

EG - Hba1c predicts CAD better than Chol.

Elevated HgbA1C (ie diabetes) is risk equivalent rather
than a risk factor.

Quoted message said:

Also, sensitivy of BP to salt predicts CAD.

Hypertension us a risk factor for CAD.

Quoted message said:

A biggie - abstaining from alcohol is a big risk
factor.

Not really. There are folks who have higher CAD risk from
drinking alcohol.

Quoted message said:

The details I include would be links to the original
research or websites.

It seems you have difficulties interpreting the
information correctly.

Quoted message said:

What is your ranking of risk factors in terms of
predictive power?

(1) Cigarette smoking.
(2) Family history
(3) Metabolic syndrome (MetS)
(4) Hypertension
(5) Dyslipidemia
(6) Age over 35 yo
(7) Male gender

Elevated HgbA1C (ie diabetes) is not a risk factor but a
risk equivalent.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

** Who is the humblest person in the universe?
makeashorterlink.commakeashorterlink.comOpen ↗

What is all this about?
makeashorterlink.commakeashorterlink.comOpen ↗

Is this spam? makeashorterlink.commakeashorterlink.comOpen ↗

Brad Sheppard said:

To clarify:

for men, Hba1c predicts mortality and CAD better than
chol, even for non-diabetics. See
vanderbiltowc.wellsource.comcontent.aspOpen ↗
and for the journal article, see bmj.bmjjournals.c-bmj.bmjjournals.c-Open ↗
om/cgi/content/abridged/322/7277/15

Those folks with higher than optimal HgbA1C likely have more
CAD because of their having metabolic syndrome (MetS). The
HgbA1C is simply a marker of MetS rather than an independent
risk factor.

Quoted message said:

Re:sensitivy of BP to salt predicts CAD - I should have
added "even for people with normal BP." Didn't know that,
did you Chung?

Saline infusion leading to the demonstration of salt
sensitivity is the most sensitive test for detecting
hypertension. Didn't know that, did you Shep?

Quoted message said:

Re: abstainance from alcohol as a risk factor add - versus
moderate drinking. Beyond moderate drinking increases
risk. "But far more Americans drink less, not more, than
would be most healthful for them. To fail to inform these
patients about the benefits of moderate drinking is both
counterproductive and dishonest. Physicians may ask, "How
much alcohol do you drink," "Is there any reason that you
don't drink (or that you drink so little)," and (to those
without religious objections, previous drinking problems,
etc.), "Do you know that one or two glasses of wine or
beer a day can be good for your health if you can safely
consume them?" acsh.orgprioritieOpen ↗
s/0801/pcyes.html

In truth, there have been no randomized double-blind placebo
controlled prospective trials to show a health benefit from
consuming alcoholic beverages.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

**
Who is the humblest person in the universe?
makeashorterlink.commakeashorterlink.comOpen ↗

What is all this about?
makeashorterlink.commakeashorterlink.comOpen ↗

Is this spam?
makeashorterlink.commakeashorterlink.comOpen ↗

"Brad Sheppard" <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

Re: abstainance from alcohol as a risk factor add - versus
moderate drinking. Beyond moderate drinking increases
risk. "But far more Americans drink less, not more, than
would be most healthful for them. To fail to inform these
patients about the benefits of moderate drinking is both
counterproductive and dishonest.

The "one glass of red wine a day" (two at most, for men) has
been the standard advice from doctors, especially to old
people, for ages in France. It has a positive effect on
cholesterol and overall heart health. It's also a relaxant,
which can relieve stress. It's slightly anti-depressant, and
depression is a real issue among old people. I guess it also
helps the "industry". You have tons of corn syrup to get rid
of, we have tons of wine. :p

"Lictor" <[email hidden]> wrote in part:

Quoted message said:

You have tons of corn syrup to get rid of, we have
tons of wine.

Care to swap some? ;-)
--
Jim Chinnis Warrenton, Virginia, USA

There is no single marker for MetS, nor is it a continuous
variable like Hba1c. More fundamental than either Mets or
Hba1c appears to be IRS - insulin resistance syndrome. This
appears to precede MetS by many years. The body pumps out
more insulin as the cells become more and more insulin
resistant. The excess insulin is harmful. Unfortunately,
there is currently no simple test for IRS.

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote
in message news:<[email hidden]>...

Quoted message said:

Brad Sheppard said:

To clarify:

for men, Hba1c predicts mortality and CAD better than
chol, even for non-diabetics. See vanderbiltowc.-vanderbiltowc.-Open ↗
wellsource.com/dh/content.asp?ID=621 and for the journal
article, see bmj.bmjjournals.comabrOpen ↗
idged/322/7277/15

Those folks with higher than optimal HgbA1C likely have
more CAD because of their having metabolic syndrome
(MetS). The HgbA1C is simply a marker of MetS rather than
an independent risk factor.

Quoted message said:

Re:sensitivy of BP to salt predicts CAD - I should have
added "even for people with normal BP." Didn't know
that, did you Chung?

Saline infusion leading to the demonstration of salt
sensitivity is the most sensitive test for detecting
hypertension. Didn't know that, did you Shep?

Quoted message said:

Re: abstainance from alcohol as a risk factor add -
versus moderate drinking. Beyond moderate drinking
increases risk. "But far more Americans drink less, not
more, than would be most healthful for them. To fail to
inform these patients about the benefits of moderate
drinking is both counterproductive and dishonest.
Physicians may ask, "How much alcohol do you drink," "Is
there any reason that you don't drink (or that you drink
so little)," and (to those without religious objections,
previous drinking problems, etc.), "Do you know that one
or two glasses of wine or beer a day can be good for
your health if you can safely consume them?" www-www-Open ↗
.acsh.org/publications/priorities/0801/pcyes.html

In truth, there have been no randomized double-blind
placebo controlled prospective trials to show a health
benefit from consuming alcoholic beverages.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

** Who is the humblest person in the universe?
makeashorterlink.commakeashorterlink.comOpen ↗

What is all this about?
makeashorterlink.commakeashorterlink.comOpen ↗

Is this spam? makeashorterlink.commakeashorterlink.comOpen ↗

Brad Sheppard said:

There is no single marker for MetS,

Did not claim that there was.

Quoted message said:

nor is it a continuous variable like Hba1c.

It is a diagnosis.

Quoted message said:

More fundamental than either Mets or Hba1c appears to be
IRS - insulin resistance syndrome.

MetS is fundamentally more important than either IRS
or HgbA1C.

Quoted message said:

This appears to precede MetS by many years.

Ime, MetS precedes IRS by several years.

Quoted message said:

The body pumps out more insulin as the cells become more
and more insulin resistant. The excess insulin is harmful.
Unfortunately, there is currently no simple test for IRS.

Clinically, MetS is more important than IRS.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

**
Who is the humblest person in the universe?
makeashorterlink.commakeashorterlink.comOpen ↗

What is all this about?
makeashorterlink.commakeashorterlink.comOpen ↗

Is this spam?
makeashorterlink.commakeashorterlink.comOpen ↗

"Brad Sheppard" <[email hidden]> píse v diskusním príspevku
"]news:[email hidden]...

Quoted message said:

I may be creating a CAD risk factors website since I can't
find in one source ALL risk factors and their details. EG
- Hba1c predicts CAD better than Chol. Also, sensitivy of
BP to salt predicts CAD. A biggie - abstaining from
alcohol is a big risk factor. The details I include would
be links to the original research or websites. What is
your ranking of risk factors in terms of predictive power?

Speaking about it, are there any studies associating
climate with CAD?

Mirek

Yes. "Mar 12 (Reuters Health) - In a study of older
women, a cold outdoor temperature at the time they were
born was associated with an increased risk of heart
disease later in life.

The findings, which are reported in the medical journal
Heart, stem from a study of 4286 women, between 60 and 79
years of age, who were randomly selected from general
physician lists in 23 British towns."

heartcenteronline.comresearchOpen ↗
detail.cfm?reutersid=4207

"Mirek Fidler" <[email hidden]> wrote in message news:<2gu9hgF6jn2uU1@uni-
berlin.de>...

Quoted message said:

"Brad Sheppard" <[email hidden]> píse v
diskusním príspevku
"]news:[email hidden]...

Quoted message said:

I may be creating a CAD risk factors website since I
can't find in one source ALL risk factors and their
details. EG - Hba1c predicts CAD better than Chol. Also,
sensitivy of BP to salt predicts CAD. A biggie -
abstaining from alcohol is a big risk factor. The
details I include would be links to the original
research or websites. What is your ranking of risk
factors in terms of predictive power?

Speaking about it, are there any studies associating
climate with CAD?

Mirek

"Brad Sheppard" <[email hidden]> píse v diskusním príspevku
"]news:[email hidden]...

Quoted message said:

Yes. "Mar 12 (Reuters Health) - In a study of older women,
a cold outdoor temperature at the time they were born was
associated with an increased risk of heart disease later
in life.

Much more interesting than I have expected.....

Mirek