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Question about depression and diet

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General fitness, health and nutrition
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6 April 2004
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11 April 2004
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Chad C.
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  1. Hi folks,

    I address this at you fine people because I follow this
    newsgroup and respect almost everybody here. I'm sorry
    if this is slightly off topic, ignore it if you wish.

    Chronic moderate depression has plagued me for the last
    5 years or so. It saps my interest in life. Makes me
    irritable, etc. I notice one thing however: when I eat
    lots of sugar and sugary items, I become very happy and
    motivated for an hour or two afterwards. That's how I
    want to feel all of the time. Reading over the Internet
    I've found this may be because of enhanced serotonin
    activity when you have an insulin rush. Now, I'm also
    trying to lose weight by eating healthy foods with low
    glycemic values, low and no sugar, plenty of fats,
    proteins, etc, in small portions all day long (about 1200-
    1500 calories). Invariably after a few days of such a
    regimen I get quite depressed. Very depressed in fact,
    and I binge eat probably 2000-3000 calories in the space
    of an hour. I immediately feel very, very good! My diet
    is varied and I take a good multivitamin, so I think I
    can rule nutritional deficiency out. I'm suspecting it
    might be the lack of refined carbohydrates that
    contributes to the huge desire for relief after a few
    days of a healthy lower carb diet. Would you folks tend
    to concur? If it's all related to serotonin, does
    evidence show that my body would begin to normalize its
    serotonin levels if I endured the lower-refined carb
    diet for an extended period of time, say a few weeks?
    I'd hate to go months and months with chronically low
    serotonin. If my body will adjust however that would
    give me some hope that sticking with it might
    cure/ameliorate my chronic depression.

    Thanks for your opinions folks,

    -Chad

    PS: What do you think about St. John's Wort as a
    treatment in my case?

  2. RE/

    Quoted message said:

    If it's all related to serotonin, does evidence show that
    my body would begin to normalize its serotonin levels if I
    endured the lower-refined carb diet for an extended period
    of time, say a few weeks? I'd hate to go months and months
    with chronically low serotonin. If my body will adjust
    however that would give me some hope that sticking with it
    might cure/ameliorate my chronic depression.

    Dunno from biochemistry, but I've been a self-described low-
    level depressive for as long as I can remember.

    Also a moderate, but not extreme binge eater.

    Food is my friend. If I feel bad, I eat to try to feel
    better. This gets a little silly sometimes when I try to eat
    myself out of an upset stomach or eat more to feel better
    because I feel so lousey after stuffing myself....

    Unfortunately, it started to catch up with me big-time this
    winter: gained 12 pounds in 3 months. Until then, I'd been
    fairly stable year-to-year - maybe five pounds every winter,
    shed every spring.

    Went full-veggie around the second week in January in a
    workaround effort - trying to at least lower the caloric
    density and stop gaining weight. I have thoughts of going
    all the way and trying Ornish's low-fat veggie...but don't
    think that'll be happening anytime soon...maybe if I feel
    good after a year or so of what I'm doing now...

    Three observations on the new eating habits:

    1) Sometimes I get *really* tired, but not enough to worry
    me....usually cured by a meal.

    2) I used to almost pass out after eating - really
    dopey. Now I generally leave the table feeling more
    alert than when I sat down. Stuffed...but alert...
    not semi-comatose.

    3) My belt has come in a full notch. Haven't weighed myself,
    but climbing hills on the bike feels better.

    4) My binging is way, way down - to the point where I'm
    actually getting to bed some nights without eating
    anything after dinner. Tried the odd chunk of
    chocolate/bowl of ice cream here and there. Just didn't
    back the same old punch..in fact the chocolate didn't
    taste very good at all.

    5) I eat what I want when I want and food tastes really
    good. I think honest physiological hunger is highly
    underrated as a food enhancer.
    --
    PeteCresswell

  3. "Chad C." <[email hidden]> wrote in message news:<[email hidden]>...

    Quoted message said:

    Hi folks,

    I address this at you fine people because I follow
    this newsgroup and respect almost everybody here. I'm
    sorry if this is slightly off topic, ignore it if you
    wish.

    Chronic moderate depression has plagued me for the
    last 5 years or so. It saps my interest in life. Makes
    me irritable, etc. I notice one thing however: when I
    eat lots of sugar and sugary items, I become very
    happy and motivated for an hour or two afterwards.
    That's how I want to feel all of the time. Reading
    over the Internet I've found this may be because of
    enhanced serotonin activity when you have an insulin
    rush. Now, I'm also trying to lose weight by eating
    healthy foods with low glycemic values, low and no
    sugar, plenty of fats, proteins, etc, in small
    portions all day long (about 1200-1500 calories).
    Invariably after a few days of such a regimen I get
    quite depressed. Very depressed in fact, and I binge
    eat probably 2000-3000 calories in the space of an
    hour. I immediately feel very, very good! My diet is
    varied and I take a good multivitamin, so I think I
    can rule nutritional deficiency out. I'm suspecting it
    might be the lack of refined carbohydrates that
    contributes to the huge desire for relief after a few
    days of a healthy lower carb diet. Would you folks
    tend to concur? If it's all related to serotonin, does
    evidence show that my body would begin to normalize
    its serotonin levels if I endured the lower-refined
    carb diet for an extended period of time, say a few
    weeks? I'd hate to go months and months with
    chronically low serotonin. If my body will adjust
    however that would give me some hope that sticking
    with it might cure/ameliorate my chronic depression.

    Thanks for your opinions folks,

    -Chad

    PS: What do you think about St. John's Wort as a
    treatment in my case?

    First, St. John's Wort or anti-depressants are hardly long
    term solutions.

    Second, I've posted several posts that deal with carbs and
    depression. See:

    groups.google.comgroups
    osting.google.com&prev=/groups%3Fhl%3Den%26lr%3D%26ie%3DUTF-
    8%26group%3Dsci.med.nutrition

    for one of my posts. You may also want to google search for
    others posts on this topic.

    TC

  4. Chad C. said:


    I address this at you fine people because I follow
    this newsgroup and respect almost everybody here. I'm
    sorry if this is slightly off topic, ignore it if you
    wish.

    Chronic moderate depression has plagued me for the
    last 5 years or so. It saps my interest in life. Makes
    me irritable, etc. I notice one thing however: when I
    eat lots of sugar and sugary items, I become very
    happy and motivated for an hour or two afterwards.
    That's how I want to feel all of the time. Reading
    over the Internet I've found this may be because of
    enhanced serotonin activity when you have an insulin
    rush.

    Interesting. Do you get much exercise?

    Quoted message said:

    Now, I'm also trying to lose weight by eating healthy
    foods with low glycemic values, low and no sugar, plenty
    of fats, proteins, etc, in small portions all day long
    (about 1200-1500 calories). Invariably after a few days
    of such a regimen I get quite depressed. Very depressed
    in fact,

    How many days, exactly?

    I get a similar reaction whenever I make a serious cut
    in my calorie intake. I feel *horrible*, but (as I
    recently discovered after a truly wretched week) it
    passes after ~5 days.

    Quoted message said:

    and I binge eat probably 2000-3000 calories in the space
    of an hour. I immediately feel very, very good!

    Yeah, not surprising.

    Quoted message said:

    My diet is varied and I take a good multivitamin, so I
    think I can rule nutritional deficiency out. I'm
    suspecting it might be the lack of refined carbohydrates
    that contributes to the huge desire for relief after a
    few days of a healthy lower carb diet. Would you folks
    tend to concur?

    It sounds to me like, well, you need carbohydrates...

    I know that for many people carbohydrates are bad, but then
    for other people they're good. If you're getting good
    quality foods, and you feel okay, and your blood test
    numbers are fine, I wouldn't suggest switching to a diet
    that makes you feel bad. Are there any natural foods that
    give you a feel-good reaction, fruits, maybe? Do starchy
    things affect how you feel?

    Quoted message said:

    If it's all related to serotonin, does evidence show
    that my body would begin to normalize its serotonin
    levels if I endured the lower-refined carb diet for an
    extended period of time, say a few weeks?

    You might adapt even faster than that, but that sounds
    reasonable.

    Quoted message said:

    I'd hate to go months and months with chronically low
    serotonin. If my body will adjust however that would
    give me some hope that sticking with it might
    cure/ameliorate my chronic depression.

    If it works, it would be worth the effort. Chronic
    depression is horrible.

    Quoted message said:

    PS: What do you think about St. John's Wort as a
    treatment in my case?

    I take St. John's Wort (as advised by my doctor). It is very
    good if your problem is overreacting. If things that get you
    down set you off into a spiral of despair, St. John's wort
    will put a stop to that. It takes 6-8 weeks to start
    working. Right away, though, it'll make you profoundly
    sleepy about 2 hours before you want to go to bed. WHENEVER
    you want to go to bed. Very annoying. That wears off
    eventually.

    I'd give it a try.

    --
    - Laurel * * * amberdine.comamberdine.com

  5. On Tue, 6 Apr 2004 10:11:57 -0700, "Chad C." <[email hidden]>
    posted:

    Quoted message said:

    Hi folks,

    I address this at you fine people because I follow this
    newsgroup and respect almost everybody here. I'm sorry
    if this is slightly off topic, ignore it if you wish.

    Chronic moderate depression has plagued me for the last
    5 years or so. It saps my interest in life. Makes me
    irritable, etc. I notice one thing however: when I eat
    lots of sugar and sugary items, I become very happy and
    motivated for an hour or two afterwards. That's how I
    want to feel all of the time. Reading over the Internet
    I've found this may be because of enhanced serotonin
    activity when you have an insulin rush. Now, I'm also
    trying to lose weight by eating healthy foods with low
    glycemic values, low and no sugar, plenty of fats,
    proteins, etc, in small portions all day long (about
    1200-1500 calories). Invariably after a few days of
    such a regimen I get quite depressed. Very depressed in
    fact, and I binge eat probably 2000-3000 calories in
    the space of an hour. I immediately feel very, very
    good! My diet is varied and I take a good multivitamin,
    so I think I can rule nutritional deficiency out. I'm
    suspecting it might be the lack of refined
    carbohydrates that contributes to the huge desire for
    relief after a few days of a healthy lower carb diet.
    Would you folks tend to concur? If it's all related to
    serotonin, does evidence show that my body would begin
    to normalize its serotonin levels if I endured the lower-
    refined carb diet for an extended period of time, say a
    few weeks? I'd hate to go months and months with
    chronically low serotonin. If my body will adjust
    however that would give me some hope that sticking with
    it might cure/ameliorate my chronic depression.

    Thanks for your opinions folks,

    -Chad

    PS: What do you think about St. John's Wort as a
    treatment in my case?

    How do you know it has anything to do with serotonin levels?
    Have you tested this hypothesis with a low GI carb diet and
    a selective serotonin reuptake inhibitor (SSRI) ?

  6. Quoted message said:

    How do you know it has anything to do with serotonin
    levels? Have you tested this hypothesis with a low GI carb
    diet and a selective serotonin reuptake inhibitor (SSRI) ?

    You're absolutely right. I have no way of knowing. I
    haven't tested my theory using the scientific method.
    There's some evidence to support the theory of
    carbohydrate (specifically, high glycemic load)
    addiction however, in general. I don't know if that's
    what plagues me or not however. All my life I've eaten
    sugar and high fructose corn syrup (and other nutritive
    sweeteners) in exceedingly high amounts, I'd peg my
    average daily intake of those substances at 25% or more,
    for about the past 10 years. I'm sure that's above
    average. And at the very least, I have an emotional
    addiction to eat foods laden with sweetness and fine
    texture. But you're right, I should be more careful
    before arriving at a conclusion. I'm really not in a
    position to know anything anyway.

    Thanks,

    Chad

  7. It is not off topic at all. If anyone says it is, they are
    mistaken. The problem maybe that you are developing
    serotonin resistance. A tablespoon of inositol powder per
    day may help restore your serotonin sensitivity. See this
    Pubmed abstracts, 11853115 and 11386498

    I'd not advise mixing this additional inositol with the use
    of a selective serotonin reuptake inhibitor drugs as
    serotonin syndrome maybe possible. I am not clear this is
    true or false but I want to cover myself with this warning.
    Use one or the other but not both together. Understand alone
    that the inositol is quite safe while alone the SSRIs drugs
    can have adverse effects such as chemical dependency.

    A normal diet contain something around the range of 500 to
    1000 milligrams of inositol. Inositol is called a B-vitamin.
    It is required by every cell in your body.

    Any chance you are developing T2 diabetes? As that condition
    is related to impaired inositol metabolism.

    These ideas may or may not work depending on what the
    underlying metabolic defect causing your depression. Or in
    short YMMV.

    William A. Noyes

    "Chad C." <[email hidden]> wrote in message
    "]news:[email hidden]...

    Quoted message said:

    Hi folks,

    I address this at you fine people because I follow
    this newsgroup and respect almost everybody here. I'm
    sorry if this is slightly off topic, ignore it if you
    wish.

    Chronic moderate depression has plagued me for the
    last 5 years or so. It saps my interest in life. Makes
    me irritable, etc. I notice one thing however: when I
    eat lots of sugar and sugary items, I become very
    happy


    and

    Quoted message said:

    motivated for an hour or two afterwards. That's how I
    want to feel all of the time. Reading over the Internet
    I've found this may be because of enhanced serotonin
    activity when you have an insulin rush. Now, I'm also
    trying to lose weight by eating healthy foods with low
    glycemic values,


    low

    Quoted message said:

    and no sugar, plenty of fats, proteins, etc, in small
    portions all day


    long

    Quoted message said:

    (about 1200-1500 calories). Invariably after a few days of
    such a regimen


    I

    Quoted message said:

    get quite depressed. Very depressed in fact, and I binge
    eat probably 2000-3000 calories in the space of an hour. I
    immediately feel very, very good! My diet is varied and I
    take a good multivitamin, so I think I can rule
    nutritional deficiency out. I'm suspecting it might be the
    lack of refined carbohydrates that contributes to the huge
    desire for relief after


    a

    Quoted message said:

    few days of a healthy lower carb diet. Would you folks
    tend to concur? If it's all related to serotonin, does
    evidence show that my body would begin to normalize its
    serotonin levels if I endured the lower-refined carb diet
    for an extended period of time, say a few weeks? I'd hate
    to go months and months with chronically low serotonin. If
    my body will adjust however that would give me some hope
    that sticking with it might cure/ameliorate my chronic
    depression.

    Thanks for your opinions folks,

    -Chad

    PS: What do you think about St. John's Wort as a
    treatment in my case?

  8. On Wed, 7 Apr 2004 17:19:45 -0700, "Chad C." <[email hidden]>
    posted:

    Quoted message said:
    Quoted message said:

    How do you know it has anything to do with serotonin
    levels? Have you tested this hypothesis with a low GI
    carb diet and a selective serotonin reuptake inhibitor
    (SSRI) ?

    You're absolutely right. I have no way of knowing. I
    haven't tested my theory using the scientific method.
    There's some evidence to support the theory of
    carbohydrate (specifically, high glycemic load)
    addiction however, in general. I don't know if that's
    what plagues me or not however. All my life I've eaten
    sugar and high fructose corn syrup (and other nutritive
    sweeteners) in exceedingly high amounts, I'd peg my
    average daily intake of those substances at 25% or
    more, for about the past 10 years. I'm sure that's
    above average. And at the very least, I have an
    emotional addiction to eat foods laden with sweetness
    and fine texture. But you're right, I should be more
    careful before arriving at a conclusion. I'm really not
    in a position to know anything anyway.

    Thanks,

    Chad


    I suggested what I would do if I were in your position. Get
    a doc to prescribe an effective SSRI and see if you could
    ameliorate your depression when carb (sweet) deprived.

  9. There are other neurotransmitters besides seratonin which
    can cause depression if their levels in your brain become
    too low. Assuming you are middle-aged or older, you should
    consider having your level of stomach acid checked
    (Heidelberg test). Almost all of the neurotransmitters
    require essential amino acids as their precursors. For the
    stomach to break down protein into simple amino acids, it
    requires a pH of 2.5 or lower. As people age, the amount of
    stomach acid that they are able to produce declines
    steadily, making it more likely that various health
    problems, including depression, will arise.

    Of course, if this hypothesis is correct in your case, you
    could take appropriate amino acid supplements to eliminate
    the depression. However, treating that single symptom,
    instead of finding and eliminating the underlying problem,
    leads to more serious health problems down the road.

    Ed Friedman

  10. 10:11:57 Tue, 6 Apr 2004sci.med.nutrition

    Chad C. at Chad C. said:


    Chronic moderate depression has plagued me for the last
    5 years or so. It saps my interest in life.

    I'm no expert... but I have read recently that a relative
    shortage of omega-3 fatty acids in the diet can lead to
    the depression symptoms you describe. Maybe try a
    supplement, or eat some foods rich in it for a few weeks
    and see what happens?

    Your sugar rush is a common-enough phenomenon and may not
    mean much. I believe you will find it doesn't happen if
    you combine your sugar intake with some protein - this
    suppresses the serotonin release and would perhaps be a
    way of testing to see if that is what is happening. See
    this article:

    news.bbc.co.uk3522903.stm

    Quoted message said:

    PS: What do you think about St. John's Wort as a
    treatment in my case?

    Who knows? But beware: St John's Wort is extremely dangerous
    (can be fatal) when used in conjunction with anything
    containing steroids (such as some anti-inflammatory
    medicines).
    --
    Martin Thompson [email hidden] (use "martin" not
    "bin"😉 London, UK Home Page: tucana.demon.co.uktucana.demon.co.uk
    Web Shop: buy.attucana Mobile Phone Ring Tones:
    ringamoby.comringamoby.com

    "Everything I do and say with anyone makes a difference."
    Gita Bellin

  11. Chad,

    check out www.iherb.com

    I have only heard good stuff about their products. Used to
    take an anti-depressant, and went through hell on them and
    still am trying to quit, so I am not supporting that idea.

    Fish - Sunlight - Meditation - Positive Thinking

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