General fitness, health and nutrition · Public discussion

There's a lot of misunderstanding about placebos

Started by Peter Moran · · Last activity · 3 posts · 451 views

This thread is locked and is currently read-only.

Thread details

What we know about this thread

Original section
General fitness, health and nutrition
Published
23 January 2004
Last activity
25 January 2004
Original author
Peter Moran
Posts
3
Discussion status
Public discussion
Total views
451
Views / 30 days
0

The navigation and discussion metadata provide context. Posts remain in their original chronological order.

Showing posts 1–3 of 3
Posts remain in their original chronological order.

Text size
  1. Worth reposting (slightly modified).

    "Rod" <[email hidden]> wrote in message news:lC_Pb.24174$Wa.17803@news-
    server.bigpond.net.au...

    Quoted message said:

    Peter,

    Much of the procedures you call AM, really deals with what Medical Science calls the "Placebo
    Effect".

    Medical science recognises a placebo effect, but much of what happens when patients get better on a
    certain treatment, whether conventional or alternative, is no "effect" at all, it is spontaneous.
    Most common medical conditions do get better by themselves or have varying levels of symptomatology.
    For example, most patients with acute back pain will be better in three weeks regardless of any
    treatment, but people can still make a living from appearing to be "treating" it.

    Quoted message said:

    The "Placebo" ( I will please) is so strong that it is the basis of Double Blinded, Placebo
    controlled Trials and Study for Medicine.

    You misunderstand. A placebo or sham treatment is used in controlled trials to "control" for all
    possible extraneous influences and confounders (and there are at least a dozen known ones), not
    because it is "strong". Studies where a placebo group has been compared with a "no treatment" group
    suggest that placebo "effects" are smaller than generally thought, at least in the context of
    conrolled trials. They have no effect on objective measures of illness but have some effect on pain
    perception and the patients' s assessment of the severity of other symptoms.

    But any effects of placebo, and the level of patient satisfaction with treatment, are not invested
    in a pill or procedure, they are a product of the whole therapeutic environment. Alternative
    medicine may appear to do better with some types of patients and some types of conditions because it
    is not constrained by many of the inhibitions which prevent doctors from exploiting placebo effects
    to the fullest. To that extent you are correct.

    It has also been well shown that patient satisfaction often bears little relationship to treatment
    efficacy. Thus patients who have been led to believe they have MCS may be thrilled to find a
    practitioner who goes along with that diagnosis, even though they are no better, and may in fact get
    worse, often becoming more and more socially isolated through intolerances that blind testing can
    show is illusory. It also must be understood that placebos have no effect on the course of cancer
    and most serious illnesses. There is some low level evidence that they can influence cardiac events.

    Quoted message said:

    So much so, that the FDA has reported - in order to gain approval for a


    new

    Quoted message said:

    drug "You don't have to run against the placebo, but you have to beat the placebo". Medical
    Science is still in an evolutionary state and the lack of understanding yet scientific use and
    acknowledgement of the "placebo


    effect"

    Quoted message said:

    is clear proof of this.

    Medical science is always evolving. There is some tension in medicine at the moment as to whether it
    can ethically exploit placebo effects more fully, as with Andrew Weil's "integrative medicine"..
    But, can we go back to more innocent times ? Fifty to sixty years ago the use of placebos was common
    and explicit within medicine, but most doctors I talk to feel that deceiving patients is wrong, and
    that better attention to and communication with patients will achieve similar outcomes . We also
    come up against informed consent issues that don't bother AM.

    Peter Moran

  2. "Peter Moran" <[email hidden]> wrote in message
    "]news:[email hidden]...

    Quoted message said:

    Worth reposting (slightly modified).

    "Rod" <[email hidden]> wrote in message news:lC_Pb.24174$Wa.17803@news-
    server.bigpond.net.au...

    Quoted message said:

    Peter,

    Much of the procedures you call AM, really deals with what Medical


    Science

    Quoted message said:
    Quoted message said:

    calls the "Placebo Effect".

    Medical science recognises a placebo effect, but much of what happens


    when

    Quoted message said:

    patients get better on a certain treatment, whether conventional or alternative, is no "effect" at
    all, it is spontaneous. Most common medical conditions do get better by themselves or have varying
    levels of symptomatology. For example, most patients with acute back pain will be better in three
    weeks regardless of any treatment, but people can still make a living from appearing to be
    "treating" it.

    The question is not about who makes a living in treating an ailment but if you insist then please
    explain the use of antibiotics in flu cases (virus), I accept if complications occur but please
    explain why antibiotics are prescribed in cases that this is not apparent.

    Quoted message said:


    Quoted message said:

    The "Placebo" ( I will please) is so strong that it is the basis of Double Blinded, Placebo
    controlled Trials and Study


    for

    Quoted message said:
    Quoted message said:

    Medicine.

    You misunderstand. A placebo or sham treatment is used in controlled trials to "control" for all
    possible extraneous influences and confounders (and there are at least a dozen known ones), not
    because it is "strong". Studies where a placebo group has been compared with a "no treatment"
    group suggest that placebo "effects" are smaller than generally thought, at least in the context
    of conrolled trials. They have no


    effect

    Quoted message said:

    on objective measures of illness but have some effect on pain perception and the patients' s
    assessment of the severity of other symptoms.

    Ah! so the placebo is common to a "sham treatment." I think you have misunderstood the placebo
    effect and categorise it as a "Sham" treatment. The Medical studies do compare the actual treatment
    to this "sham" treatment, do they not ? It does seem that it is sort of comparing "Good" to "Evil"
    and that is the way it is convryrd by conventional medicine and its indoctrinates.

    Quoted message said:


    But any effects of placebo, and the level of patient satisfaction with treatment, are not invested
    in a pill or procedure, they are a product


    of

    Quoted message said:

    the whole therapeutic environment. Alternative medicine may appear to do better with some types of
    patients and some types of conditions because it is not constrained by many of the inhibitions
    which prevent doctors from exploiting placebo effects to the fullest. To that extent you are


    correct.

    Thank you and it still goes on today despite what others say. Doctors prescribe placebos for the flu
    virus don't they ? It is not just limited to that either as you well know.

    Quoted message said:


    It has also been well shown that patient satisfaction often bears little relationship to treatment
    efficacy. Thus patients who have been led to believe they have MCS may be thrilled to find a
    practitioner who goes along with that diagnosis, even though they are no better, and may in fact
    get worse,


    often

    Quoted message said:

    becoming more and more socially isolated through intolerances that blind testing can show is
    illusory. It also must be understood that placebos have no effect on the course of cancer and most
    serious illnesses. There is some low level evidence that they can influence cardiac events.

    Yes we all know that mental state has a bearing on overall health. We also know that a caring
    attitude and response by practitioners also engenders "Feel good" responses. Can you explain the
    placebo effect where surgery is concerned ?

    Quoted message said:


    Quoted message said:

    So much so, that the FDA has reported - in order to gain approval for a


    new

    Quoted message said:

    drug "You don't have to run against the placebo, but you have to beat


    the

    Quoted message said:
    Quoted message said:

    placebo". Medical Science is still in an evolutionary state and the lack of understanding yet
    scientific use and acknowledgement of the "placebo


    effect"

    Quoted message said:

    is clear proof of this.

    Medical science is always evolving. There is some tension in medicine at the moment as to whether
    it can ethically exploit placebo effects more fully, as with Andrew Weil's "integrative
    medicine".. But, can we go back to more innocent times ? Fifty to sixty years ago the use of
    placebos was common and explicit within medicine, but most doctors I talk to feel that deceiving
    patients is wrong, and that better attention to and


    communication

    Quoted message said:

    with patients will achieve similar outcomes . We also come up against informed consent issues that
    don't bother AM.

    Once again where is the proof that Doctors do not use Placebos. We know they do in the cases of flu
    and there is indication that a great deal of depression is also treated with drugs that get a
    similar response rate to placebos. In fact the overall concern is an abuse of antibiotics in most
    western nations along with anti-depressants.

    My concern is that drugs (treatments) may have taken over for the caring attitude needed to impact
    conditions.

    Peter, blood letting used to be the favoured treatment long ago, now drugs are the favoured
    treatment in most cases, I hope that you agree that in the future we may have a different aproach
    with a much different result. Yes I agree that the drug results are more favourable than the blood
    letting of yester year which points to tomorrow's treatments being quite different than todays
    treatments. This is where conventional and alternative need to combine which of course is happening
    daily. Informed consent issues are something that may apply to uninformed people but not the vast
    majority that seek solutions to health problems. After all when you are seeking solutions, the
    homework has been done usually quite well after receiving informed opinions.

    Thanks, Rod.

    Quoted message said:


    Peter Moran

  3. "Rod" <[email hidden]> wrote in message
    "]news:[email hidden]...

    Quoted message said:


    "Peter Moran" <[email hidden]> wrote in message


    "]news:[email hidden]...

    Quoted message said:
    Quoted message said:

    Worth reposting (slightly modified).

    "Rod" <[email hidden]> wrote in message news:lC_Pb.24174$Wa.17803@news-
    server.bigpond.net.au...

    Quoted message said:

    Peter,

    Much of the procedures you call AM, really deals with what Medical


    Science

    Quoted message said:
    Quoted message said:

    calls the "Placebo Effect".

    Medical science recognises a placebo effect, but much of what happens


    when

    Quoted message said:

    patients get better on a certain treatment, whether conventional or alternative, is no "effect"
    at all, it is spontaneous. Most common medical conditions do get better by themselves or have
    varying levels of symptomatology. For example, most patients with acute back pain will be better
    in three weeks regardless


    of

    Quoted message said:
    Quoted message said:

    any treatment, but people can still make a living from appearing to be "treating" it.

    The question is not about who makes a living in treating an ailment but if you insist then please
    explain the use of antibiotics in flu cases


    (virus),

    Quoted message said:

    I accept if complications occur but please explain why antibiotics are prescribed in cases that
    this is not apparent.

    There is indeed an element of "pleasing the patient" in that, as most patients go to the doctor with
    the flu in the expectation of being prescribed antibiotics, and doctors find it easier to go with
    the flow rather than spending time explaining the issues to the patient. I won't defend doctors who
    are unselective in that regard. Is it conscious usage of placebo in its usual sense? Arguable. We
    would call it inappropriate prescribing and a lot of effort is going into reducing antibiotic
    prescribing in such contexts.

    Quoted message said:
    Quoted message said:


    Quoted message said:

    The "Placebo" ( I will please) is so strong that it is the basis of Double Blinded, Placebo
    controlled Trials and Study


    for

    Quoted message said:
    Quoted message said:

    Medicine.

    You misunderstand. A placebo or sham treatment is used in controlled trials to "control" for all
    possible extraneous influences and


    confounders

    Quoted message said:
    Quoted message said:

    (and there are at least a dozen known ones), not because it is "strong". Studies where a
    placebo group has been compared with a "no treatment" group suggest that placebo "effects" are
    smaller than


    generally

    Quoted message said:
    Quoted message said:

    thought, at least in the context of conrolled trials. They have no


    effect

    Quoted message said:

    on objective measures of illness but have some effect on pain


    perception

    Quoted message said:
    Quoted message said:

    and the patients' s assessment of the severity of other symptoms.

    Ah! so the placebo is common to a "sham treatment." I think you have misunderstood the placebo
    effect and categorise it as a "Sham" treatment. The Medical studies do compare the actual
    treatment to this "sham" treatment, do they not ? It does seem that it is sort of comparing "Good"
    to "Evil" and that is the way it is convryrd by conventional medicine and its indoctrinates.

    I don't understand your point. A placebo, as used in controlled trials is by definition a sham
    treatment or "dummy" treatment.. . It is neither good nor evil. What alternative practitioners
    do is not strictly speaking a placebo at all, if they think their treatments have intrinsic
    medical activity.

    We can however be fairly certain that most of the "effects" they observe are due to the same
    complex mixture of phenomena that can result in fifty per cent or more resolution *of some
    conditions only* in patients receiving dummy treatments in controlled trials. Only they are
    exagerated in the practitioner's mind, because another layer of biases is superimposed on the data
    , such as that patients who are not helped or made worse don't come back. The practitioner has
    little consciouness of them, and there is that natural human tendecy to find excuses for any
    failures they are aware of..

    The shorthand expression "placebo effect" is regrettably often used instead of the awkward
    descriptive in the last paragraph, but it is obviously misleading you and others because it is
    mostly not an "effect" at all. On no treatment at all many patients with anxiety or depression or
    the irritable bowel syndrome will be better at any later end-point.

    Quoted message said:
    Quoted message said:


    But any effects of placebo, and the level of patient satisfaction with treatment, are not
    invested in a pill or procedure, they are a product


    of

    Quoted message said:

    the whole therapeutic environment. Alternative medicine may appear to


    do

    Quoted message said:
    Quoted message said:

    better with some types of patients and some types of conditions because


    it

    Quoted message said:
    Quoted message said:

    is not constrained by many of the inhibitions which prevent doctors from exploiting placebo
    effects to the fullest. To that extent you are


    correct.

    Thank you and it still goes on today despite what others say. Doctors prescribe placebos for the
    flu virus don't they ? It is not just limited


    to

    Quoted message said:

    that either as you well know.

    Quoted message said:


    It has also been well shown that patient satisfaction often bears little relationship to
    treatment efficacy. Thus patients who have been led to believe they


    have

    Quoted message said:
    Quoted message said:

    MCS may be thrilled to find a practitioner who goes along with that diagnosis, even though they
    are no better, and may in fact get worse,


    often

    Quoted message said:

    becoming more and more socially isolated through intolerances that blind testing can show is
    illusory. It also must be understood that


    placebos

    Quoted message said:
    Quoted message said:

    have no effect on the course of cancer and most serious illnesses.


    There

    Quoted message said:
    Quoted message said:

    is some low level evidence that they can influence cardiac events.

    Yes we all know that mental state has a bearing on overall health.

    Which sections of alternative medicine tend to exaggerate, while others refuse to accept that
    psychological factors can make them ill.

    Quoted message said:

    We also know that a caring attitude and response by practitioners also engenders "Feel good"
    responses. Can you explain the placebo effect where surgery is concerned ?

    The more dramatic the treatment, the more expensive, and the more hands-on it is the more likely you
    are to have patients reporting positive responses. We haven't here even started to dissect out what
    a "patient reporting a positive response" means. There are plenty of factors: misperceptions,
    biases, distractions, variations in attentiveness to symptoms, experimental subordination, "answers
    of politeness", cognitive dissonance, psychosomatic triggering, that can make an inert treatment
    appear successful.

    Quoted message said:
    Quoted message said:


    Quoted message said:

    So much so, that the FDA has reported - in order to gain approval for


    a

    Quoted message said:
    Quoted message said:

    new

    Quoted message said:

    drug "You don't have to run against the placebo, but you have to beat


    the

    Quoted message said:
    Quoted message said:

    placebo". Medical Science is still in an evolutionary state and the lack of understanding yet
    scientific use and acknowledgement of the "placebo


    effect"

    Quoted message said:

    is clear proof of this.

    Medical science is always evolving. There is some tension in medicine


    at

    Quoted message said:
    Quoted message said:

    the moment as to whether it can ethically exploit placebo effects more fully, as with Andrew
    Weil's "integrative medicine".. But, can we go


    back

    Quoted message said:
    Quoted message said:

    to more innocent times ? Fifty to sixty years ago the use of placebos


    was

    Quoted message said:
    Quoted message said:

    common and explicit within medicine, but most doctors I talk to feel


    that

    Quoted message said:
    Quoted message said:

    deceiving patients is wrong, and that better attention to and


    communication

    Quoted message said:

    with patients will achieve similar outcomes . We also come up against informed consent issues
    that don't bother AM.

    Once again where is the proof that Doctors do not use Placebos. We know


    they

    Quoted message said:

    do in the cases of flu and there is indication that a great deal of depression is also treated
    with drugs that get a similar response rate to placebos. In fact the overall concern is an abuse
    of antibiotics in most western nations along with anti-depressants.

    I don't deny any of that. Whether a doctor knows it or not (I initially said "conventional and
    alternative"😉 medical practice is always going to be riddled with placebo effects. All I said
    was that the conscious and deliberate usage of placebos is frowned upon by most of the doctors
    I talk to.

    The main area where I suspect we would disagree is the potency of such effects. Placebos are never
    going to provide the answer to any of medicine's pressing problems.

    Peter Moran

    Quoted message said:


    My concern is that drugs (treatments) may have taken over for the caring attitude needed to impact
    conditions.

    Peter, blood letting used to be the favoured treatment long ago, now drugs are the favoured
    treatment in most cases, I hope that you agree that in


    the

    Quoted message said:

    future we may have a different aproach with a much different result. Yes


    I

    Quoted message said:

    agree that the drug results are more favourable than the blood letting of yester year which points
    to tomorrow's treatments being quite different


    than

    Quoted message said:

    todays treatments. This is where conventional and alternative need to combine which of course is
    happening daily. Informed consent issues are something that may apply


    to

    Quoted message said:

    uninformed people but not the vast majority that seek solutions to health problems. After all when
    you are seeking solutions, the homework has been done usually quite well after receiving informed
    opinions.

    Thanks, Rod.

    Quoted message said:


    Peter Moran

Active in the last 60 minutes

Active in this thread

0 users · 0 guests ·0 bots ·0 total

No signed-in users are active right now.

No known search crawlers active right now.