Actos?

"Um..." <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

Should a person who is sucessfully controlling their blood sugar with diet and exercise be
taking actos? If so, why? If not, why not? Thanks.

What do you mean by successfully? If your BG is in non-diabetic range, then I see no need for it.
You should consider taking Metformin for the benefits it offers the heart. But not Actos. If your BG
is not in range, take whatever you need.

--
Type 2 users.bestweb.net~jboveOpen ↗

"Julie Bove" <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

"Um..." <[email hidden]> wrote in message "]news:[email hidden]...

Quoted message said:

Should a person who is sucessfully controlling their blood sugar

with

Quoted message said:

Quoted message said:

diet and exercise be taking actos? If so, why? If not, why not? Thanks.

What do you mean by successfully?

T2 with fasting BS normal, AC1(?) normal, no spikes over 100 or so after meals.

Quoted message said:

If your BG is in non-diabetic range, then I see no need for it.

My doctor seems to think that taking it, even with good numbers, will protect my future ability
to produce and handle insulin. I think it makes me feel bad and is causing a weight gain. I need
to be able to tell her why I think I don't need it, but the only information I can find on it
seems to be from the drug company.

"Um..." <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

"Julie Bove" <[email hidden]> wrote in message "]news:[email hidden]...

Quoted message said:

"Um..." <[email hidden]> wrote in message "]news:[email hidden]...

Quoted message said:

Should a person who is sucessfully controlling their blood sugar

with

Quoted message said:

Quoted message said:

diet and exercise be taking actos? If so, why? If not, why not?

Thanks.

Quoted message said:

Quoted message said:

What do you mean by successfully?

T2 with fasting BS normal, AC1(?) normal, no spikes over 100 or so

after

Quoted message said:

meals.

Quoted message said:

If your BG is in non-diabetic range, then I see no need for it.

My doctor seems to think that taking it, even with good numbers, will
protect my future ability to produce and handle insulin. I think it makes

me

Quoted message said:

feel bad and is causing a weight gain. I need to be able to tell her why I think I don't need it,
but the only information I can find on it seems to

be

Quoted message said:

from the drug company.

If you are currently taking it, then it would appear that you need it to keep your numbers down.
Unless you are getting frequent hypos that is, and you don't mention that. I have never heard that
it will protect your future ability to produce and handle insulin and in fact it is not the first
drug of choice. Are you seeing an Endocrinologist? If not, you probably should. IMO, Metformin is
the better drug to start with. Even if you don't need it for BG control, it offers other benefits
and can be taken at a low dose. Some people can't handle it though because of the stomach upset it
can cause.

--
Type 2 users.bestweb.net~jboveOpen ↗

"Julie Bove" <[email hidden]> wrote :

Quoted message said:

If you are currently taking it, then it would appear that you need it to keep your numbers down.

No, my numbers were down, then she put me on it. I just started with her and I suspect she is
just being carefull.

Um... wrote in message ...

Quoted message said:

"Julie Bove" <[email hidden]> wrote in message "]news:[email hidden]...

Quoted message said:

"Um..." wrote:

Quoted message said:

Quoted message said:

...

. . .(snip). . .. My doctor seems to think that taking it, even with good numbers, will protect my
future ability to produce and handle insulin. I think it makes

me

Quoted message said:

feel bad and is causing a weight gain. I need to be able to tell her why I think I don't need it,
but the only information I can find on it seems to

be

Quoted message said:

from the drug company. . . .(snip). . .

Damaged beta cells with accompanying insulin defficiency are the immediate cause of
much/most/all (??) Type 2 diabetes. There is fragmentary evidence that the TZD's (Actos,
Avandia, Rezulin) actually help rejuvenate the damaged beta cells, i.e.

"-----Original Message----- From: William C Biggs MD Newsgroups: misc.health.diabetes Date: Sunday,
September 01, 2002 9:56 PM Subject: Re: Avandia and islet cells

. . .(snip). . .

There is speculation that rosiglitizone may actually regenerate islet cells.

I can email you a jpg from a presentation I gave on this that compares rosiglitizone to controls,
metformin, and glyburide. The original reference is Lister CA et al. Diabetologia 1999;42(suppl
1):A150 (abstr 556) from a poster at the 1999 EASD in Brussels.

The jpg shows mouse islet cells in db/db mice (mice bred to develop type 2 DM when overfed) treated
with each drug. EMail me with your address and I will forward it to you. My spammotel address is a
working address....unless it is spam.

Cheers,

William C Biggs, MD"

They are taking another look at this in the DREAM clinical trials being managed by docs at McMasters
Univ. in Toronto.

dtu.ox.ac.ukindex.htmlOpen ↗

". . . .Rosiglitazone improves insulin sensitivity and may have a beta cell cytoprotective
effect . . ."

In any case, anything you do to reduce the amount of self-generated insulin you make, for any
reason, and by any technique seems to protect your future ability to manufacture insulin, i.e..

joplink.net02.htmlOpen ↗

That means low carb, lose fat lb, gain muscle lb, exercise vigorously, metformin, TZD's and
injecting insulin even if you don't really seem to really need it for good control.

That's a shopping basket full of things to do to protect your beta cells. Don't do anything and you
may lose enough cells to end up in the heavy duty insulin injection regime we T1's are forced to use
(account for every mouthful of carb and every unit of insulin or suffer serious consequences). Pick,
and chose the right ones (ask your genes about the "right ones"😉 and you may not need my type of
insulin therapy until your 120th birthday.

Regards
Old Al

Actos can occasionally cause various nasty side effects including macular edema (a cause of
blindness), heart failure, and liver problems.

If you don't need it, there is zero reason to take it or any other drug. None of these newer drugs
have been on the market long enough for the true long term side effects to be fully understood. A
sane approach is to take as little as possible of any drug unless you cannot control your blood
sugar any other way.

-- Jenny - Low Carbing for 4 years. At goal for weight. Type 2 diabetes, hba1c 5.2. Cut the carbs to
respond to my email address!

Low carb facts and figures, my weight-loss photos, tips, recipes, strategies for dealing with
diabetes and more at geocities.comjenny the beanOpen ↗

Looking for help controlling your blood sugar? Visit alt-support-alt-support-Open ↗
diabetes.org/Newly%20Diagnosed.htm

"Um..." <[email hidden]> wrote in message "]news:[email hidden]...

Quoted message said:

"Julie Bove" <[email hidden]> wrote :

Quoted message said:

If you are currently taking it, then it would appear that you need it to keep your numbers down.

No, my numbers were down, then she put me on it. I just started with

her

Quoted message said:

and I suspect she is just being carefull.

On Sat, 17 Jan 2004 10:59:28 -0500, "Jenny" <[email hidden]>

Quoted message said:

Actos can occasionally cause various nasty side effects including macular edema (a cause of
blindness), heart failure, and liver problems.

If you don't need it, there is zero reason to take it or any other drug. None of these newer drugs
have been on the market long enough for the true long term side effects to be fully understood. A
sane approach is to take as little as possible of any drug unless you cannot control your blood
sugar any other way.

-- Jenny -

And why the hell would anyone take any medication if they could control their blood sugar any other
way? Or is this the old BS line, that T2s take meds because it allows them to eat things they
shouldn't? WRONG!

SM

-----------------------------------------------
Let's Kick the Right Wing, Out of the West Wing
-----------------------------------------------

T2s take medications before trying other methods of controlling their blood sugars because their
family doctors prescribe the drugs as soon as they are diagnosed and do not discuss other methods
of control.

If you don't believe that, I have to wonder what planet you are living on.

-- Jenny - Low Carbing for 4 years. At goal for weight. Type 2 diabetes, hba1c 5.2. Cut the carbs to
respond to my email address!

Low carb facts and figures, my weight-loss photos, tips, recipes, strategies for dealing with
diabetes and more at geocities.comjenny the beanOpen ↗

Looking for help controlling your blood sugar? Visit alt-support-alt-support-Open ↗
diabetes.org/Newly%20Diagnosed.htm

"Sleepyman" <[email hidden]> wrote in message "]news:[email hidden]...

Quoted message said:

Jenny said:

Actos can occasionally cause various nasty side effects including

macular

Quoted message said:

Quoted message said:

edema (a cause of blindness), heart failure, and liver problems.

If you don't need it, there is zero reason to take it or any other drug. None of these newer
drugs have been on the market long enough for the

true

Quoted message said:

Quoted message said:

long term side effects to be fully understood. A sane approach is to

take

Quoted message said:

Quoted message said:

as little as possible of any drug unless you cannot control your blood

sugar

Quoted message said:

Quoted message said:

any other way.

-- Jenny -

And why the hell would anyone take any medication if they could control their blood sugar any
other way? Or is this the old BS line, that T2s take meds because it allows them to eat things
they shouldn't? WRONG!

SM

-----------------------------------------------
Let's Kick the Right Wing, Out of the West Wing
-----------------------------------------------

"Jenny" <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

T2s take medications before trying other methods of controlling their

blood sugars because their family doctors prescribe the drugs as soon as they are diagnosed and do
not discuss other methods of control.

Quoted message said:

Mine didn't. She referred me to a CDE & recommended diet & exercise. Didn't mention anything else,
and since the d&e works, hasn't yet. Nor has my endo, whom I started seeing because of thyroid
(cancer). But I am now (at my request to endo) experimenting with Prandin for dinner, so I can have
more variety and, especially in winter, more "stodge". bj

On Sun, 18 Jan 2004 11:37:25 -0500, "Jenny" <[email hidden]>

Quoted message said:

T2s take medications before trying other methods of controlling their blood sugars because their
family doctors prescribe the drugs as soon as they are diagnosed and do not discuss other methods
of control.

If you don't believe that, I have to wonder what planet you are living on.

-- Jenny -

On my planet, most newly diagnosed diabetics are put on medication because their BGs are out of
control. On yours, they aren't?

SM

-----------------------------------------------
Let's Kick the Right Wing, Out of the West Wing
-----------------------------------------------

In article <[email hidden]>,

Sleepyman said:

Jenny said:

T2s take medications before trying other methods of controlling their blood sugars because their
family doctors prescribe the drugs as soon as they are diagnosed and do not discuss other methods
of control.

If you don't believe that, I have to wonder what planet you are living on.

-- Jenny -

On my planet, most newly diagnosed diabetics are put on medication because their BGs are out of
control. On yours, they aren't?

On my planet, at least in my country, most newly diagnosed diabetics aren't put on medication right
away, simply because they typically have to wait up to 2 months for a doctors appointment following
diagnosis.

--
AF "Non Sequitur U has a really, really lousy debate team." --artyw raises the bar on
rec.sport.baseball

In article <[email hidden]>,

Alice Faber said:

In article said:

Jenny said:

T2s take medications before trying other methods of controlling their blood sugars because
their family doctors prescribe the drugs as soon as they are diagnosed and do not discuss other
methods of control.

If you don't believe that, I have to wonder what planet you are living on.

-- Jenny -

On my planet, most newly diagnosed diabetics are put on medication because their BGs are out of
control. On yours, they aren't?

On my planet, at least in my country, most newly diagnosed diabetics aren't put on medication
right away, simply because they typically have to wait up to 2 months for a doctors appointment
following diagnosis.

On my planet, this newly-diagnosed diabetic had her diabetes denied by her doctor because she'd
started treating herself with diet and successfully returned her numbers to the normal range, and
she had to go find an endocrinologist who would recognize what was happening with her body.

Priscilla