Vitamin E

"francispoon" <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

I was advised by my doctor that 50 mg a day of this Vitamin E is better than an aspirin a day.

Is there any truth there?

THX

FP

It seems like strange advice to me. Aspirin is pretty well proven. Vitamin E is more speculative in
its benefits and I don't believe works the same way. But seek other opinions beyond mine.

Bill

5 Jan 2004 05:02:20 -0800 in article
<[email hidden]> [email hidden]

(francispoon) said:

I was advised by my doctor that 50 mg a day of this Vitamin E is better than an aspirin a day.

Is there any truth there?

I'm not sure. Information from clinical trials tells that aspirin is more effective than vitamin E.
But vitamin E may have its benefits, too. One trial showed benefit from taking time release vitamin
C _and_ vitamin E twice a day. It may be advisable to choose a vitamin E supplement which in
addition to alpha-tocopherol contains also gamma-tocopherol and other tocopherols, preferably also
tocotrienols.

50 mg of vitamin E sounds a bit low when used as supplement. Usually one takes about 200-400 mg/d.

--
Matti Narkia

francispoon said:

I was advised by my doctor that 50 mg a day of this Vitamin E is better than an aspirin a day.

Is there any truth there?

No.

Quoted message said:

THX

FP

You are welcome.

Humbly,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

Mon, 05 Jan 2004 15:18:57 +0200 in article
<[email hidden]> Matti Narkia

Quoted message said:

It may be advisable to choose a vitamin E supplement which in addition to alpha-tocopherol contains
also gamma-tocopherol and other tocopherols, preferably also tocotrienols.

For information about tocotrienols, see for example

Tocotrienols <URL:http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/toc_0254.shtml>

Tocotrienol.org <URL:http://www.tocotrienol.org/index.html>

Intramedicine Consumer Monograph -- Tocotrienols
<URL:http://content.intramedicine.com/LNR/monographs/conVMNH.asp?objID=100189&mtyp=vmn>

Tocotrienols <URL:http://www.nutrition.org/cgi/content/full/132/9/2494#SEC5>

( from

Kerckhoffs DA, Brouns F, Hornstra G, Mensink RP. Effects on the human serum lipoprotein profile
of beta-glucan, soy protein and isoflavones, plant sterols and stanols, garlic and tocotrienols.
J Nutr. 2002 Sep;132(9):2494-505. Review.
<URL:http://www.nutrition.org/cgi/content/full/132/9/2494> )

--
Matti Narkia

francispoon schrieb:

Quoted message said:

I was advised by my doctor that 50 mg a day of this Vitamin E is better than an aspirin a day.

Is there any truth there?

In several large cohort studies, for example the Health Professionals Follow Up Study and the
Nurses' Health Study, the use of vitamin E supplements was associated with a substantially reduced
risk of coronary heart disease.

From the Nurses' Health Study:

"Results As compared with women in the lowest fifth of the cohort with respect to vitamin E intake,
those in the top fifth had a relative risk of major coronary disease of 0.66 (95 percent confidence
interval, 0.50 to 0.87) after adjustment for age and smoking. Further adjustment for a variety of
other coronary risk factors and nutrients, including other antioxidants, had little effect on the
results. Most of the variability in intake and reduction in risk was attributable to vitamin E
consumed as supplements. Women who took vitamin E supplements for short periods had little apparent
benefit, but those who took them for more than two years had a relative risk of major coronary
disease of 0.59 (95 percent confidence interval, 0.38 to 0.91) after adjustment for age, smoking
status, risk factors for coronary disease, and use of other antioxidant nutrients (including
multivitamins). "

content.nejm.org1444Open ↗
dbf5&keytype2=tf_ipsecsha

(tinyurl.com2qk5rOpen ↗)

Most clinical trials (mostly secondary prevention trials) didn't show a reduced incidence in heart
disease in users of vitamin E supplements.

Some possible reasons for this are discussed in:

ajcn.org703Open ↗

According to the Health Professionals Follow Up Study and the Nurses' Health Study 50 mg is probably
not enough to protect from heart disease. 200 mg seem to be a reasonable amount to take.

If you decide to take a supplement, make sure that the vitamin E comes from a natural sources.
Synthetic vitamin E is less effective and is probably a waste of money.

Bottomline:

Research suggests that vitamin E can reduce the risk of coronary heart disease, at least in primary
prevention. So does aspirin. However, as both probably don't work by the same mechanism, there seems
to be no reason why someone should not take aspirin when they take vitamin E. So you might want to
consider taking both.

Thorsten

--
"Nothing in biology makes sense, except in the light of evolution"

(Theodosius Dobzhansky)

Mon, 05 Jan 2004 15:18:57 +0200 in article
<[email hidden]> Matti Narkia

Quoted message said:

It may be advisable to choose a vitamin E supplement which in addition to alpha-tocopherol contains
also gamma-tocopherol and other tocopherols, preferably also tocotrienols.

Blow some references which seem to suggest that gamma-tocopherol (and delta-tocopherol) should be
taken together with alpha-tocopherol:

1: Huang HY, Appel LJ. Supplementation of diets with alpha-tocopherol reduces serum concentrations
of gamma- and delta-tocopherol in humans. J Nutr. 2003 Oct;133(10):3137-40. PMID: 14519797
[PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&-
db=PubMed&list_uids=14519797&dopt=Abstract>

2: Jiang Q, Ames BN. Gamma-tocopherol, but not alpha-tocopherol, decreases proinflammatory
eicosanoids and inflammation damage in rats. FASEB J. 2003 May;17(8):816-22. PMID: 12724340
[PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&-
db=PubMed&list_uids=12724340&dopt=Abstract>

3: Jiang Q, Christen S, Shigenaga MK, Ames BN. gamma-tocopherol, the major form of vitamin E in the
US diet, deserves more attention. Am J Clin Nutr. 2001 Dec;74(6):714-22. Review. PMID: 11722951
[PubMed - indexed for MEDLINE] <URL:http://www.ajcn.org/cgi/content/full/74/6/714>

4: Jiang Q, Elson-Schwab I, Courtemanche C, Ames BN. gamma-tocopherol and its major metabolite, in
contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial
cells. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11494-9. PMID: 11005841 [PubMed - indexed
for MEDLINE]

5: Li D, Saldeen T, Romeo F, Mehta JL. Relative Effects of alpha- and gamma-Tocopherol on Low-
Density Lipoprotein Oxidation and Superoxide Dismutase and Nitric Oxide Synthase Activity and
Protein Expression in Rats. J Cardiovasc Pharmacol Ther. 1999 Oct;4(4):219-226. PMID: 10684543
[PubMed - as supplied by publisher] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retr-
ieve&db=PubMed&list_uids=10684543&dopt=Abstract>

6: Kontush A, Spranger T, Reich A, Baum K, Beisiegel U. Lipophilic antioxidants in blood plasma as
markers of atherosclerosis: the role of alpha-carotene and gamma-tocopherol. Atherosclerosis.
1999 May;144(1):117-22. PMID: 10381285 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.-
nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10381285&dopt=Abstract>

7: Wolf G. gamma-Tocopherol: an efficient protector of lipids against nitric oxide-initiated
peroxidative damage. Nutr Rev. 1997 Oct;55(10):376-8. Review. PMID: 9354084 [PubMed - indexed
for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uid-
s=9354084&dopt=Abstract>

8: Christen S, Woodall AA, Shigenaga MK, Southwell-Keely PT, Duncan MW, Ames BN. gamma-tocopherol
traps mutagenic electrophiles such as NO(X) and complements alpha-tocopherol: physiological
implications. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3217-22. PMID: 9096373 [PubMed -
indexed for MEDLINE] <URL:http://www.pnas.org/cgi/content/full/94/7/3217>

--
Matti Narkia

On Mon, 5 Jan 2004 14:39:52 -0500, Dr. Andrew B. Chung, MD/PhD wrote
(in message <[email hidden]>😉:

Quoted message said:

francispoon said:

I was advised by my doctor that 50 mg a day of this Vitamin E is better than an aspirin a day.

Is there any truth there?

No.

So let me make sure I understand this... you are calling Francis' doctor a liar. Is that about the
size of it?

--
Weeding the Lord's vinyards since 2003

Steve

Thorsten Schier said:

francispoon schrieb:

Quoted message said:

I was advised by my doctor that 50 mg a day of this Vitamin E is better than an aspirin a day.

Is there any truth there?

In several large cohort studies, for example the Health Professionals Follow Up Study and the
Nurses' Health Study, the use of vitamin E supplements was associated with a substantially reduced
risk of coronary heart disease.

Oh, gee. Chung said, "No."

Could this be another example of Chung's "advice" being in conflict with actual science?

Color me shocked. Here comes Chung with his "It depends on what is, is" line of reasoning.

Pastorio

Quoted message said:

From the Nurses' Health Study:

"Results As compared with women in the lowest fifth of the cohort with respect to vitamin E
intake, those in the top fifth had a relative risk of major coronary disease of 0.66 (95 percent
confidence interval, 0.50 to 0.87) after adjustment for age and smoking. Further adjustment for a
variety of other coronary risk factors and nutrients, including other antioxidants, had little
effect on the results. Most of the variability in intake and reduction in risk was attributable to
vitamin E consumed as supplements. Women who took vitamin E supplements for short periods had
little apparent benefit, but those who took them for more than two years had a relative risk of
major coronary disease of 0.59 (95 percent confidence interval, 0.38 to 0.91) after adjustment for
age, smoking status, risk factors for coronary disease, and use of other antioxidant nutrients
(including multivitamins). "

content.nejm.org1444Open ↗
87dbf5&keytype2=tf_ipsecsha

(tinyurl.com2qk5rOpen ↗)

Most clinical trials (mostly secondary prevention trials) didn't show a reduced incidence in heart
disease in users of vitamin E supplements.

Some possible reasons for this are discussed in:

ajcn.org703Open ↗

According to the Health Professionals Follow Up Study and the Nurses' Health Study 50 mg is
probably not enough to protect from heart disease. 200 mg seem to be a reasonable amount to take.

If you decide to take a supplement, make sure that the vitamin E comes from a natural sources.
Synthetic vitamin E is less effective and is probably a waste of money.

Bottomline:

Research suggests that vitamin E can reduce the risk of coronary heart disease, at least in
primary prevention. So does aspirin. However, as both probably don't work by the same mechanism,
there seems to be no reason why someone should not take aspirin when they take vitamin E. So you
might want to consider taking both.

Thorsten

Mon, 05 Jan 2004 22:33:39 +0200 in article
<[email hidden]> Matti Narkia

Quoted message said:

4: Jiang Q, Elson-Schwab I, Courtemanche C, Ames BN. gamma-tocopherol and its major metabolite, in
contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial
cells. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11494-9. PMID: 11005841 [PubMed - indexed
for MEDLINE]

And the link is

<URL:http://www.pnas.org/cgi/content/full/94/7/3217>

--
Matti Narkia

Mon, 05 Jan 2004 22:33:39 +0200 in article
<[email hidden]> Matti Narkia

Quoted message said:

Mon, 05 Jan 2004 15:18:57 +0200 in article <[email hidden]> Matti

Narkia said:

It may be advisable to choose a vitamin E supplement which in addition to alpha-tocopherol
contains also gamma-tocopherol and other tocopherols, preferably also tocotrienols.

Blow some references which seem to suggest that gamma-tocopherol (and delta-tocopherol) should be
taken together with alpha-tocopherol:

1: Huang HY, Appel LJ. Supplementation of diets with alpha-tocopherol reduces serum concentrations
of gamma- and delta-tocopherol in humans. J Nutr. 2003 Oct;133(10):3137-40. PMID: 14519797
[PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve-
&db=PubMed&list_uids=14519797&dopt=Abstract>

Here's a similar older study:

Handelman GJ, Machlin LJ, Fitch K, Weiter JJ, Dratz EA. Oral alpha-tocopherol supplements decrease
plasma gamma-tocopherol levels in humans. J Nutr. 1985 Jun;115(6):807-13. PMID: 3998871 [PubMed -
indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list-
_uids=3998871&dopt=Abstract>

--
Matti Narkia

Matti Narkia said:

Mon, 05 Jan 2004 15:18:57 +0200 in article <[email hidden]> Matti

Narkia said:

It may be advisable to choose a vitamin E supplement which in addition to alpha-tocopherol
contains also gamma-tocopherol and other tocopherols, preferably also tocotrienols.

Blow some references which seem to suggest that gamma-tocopherol (and delta-tocopherol) should be
taken together with alpha-tocopherol:

Yes, you seem to be blowing.

Humbly,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

Mon, 05 Jan 2004 22:33:39 +0200 in article
<[email hidden]> Matti Narkia

Quoted message said:

Mon, 05 Jan 2004 15:18:57 +0200 in article <[email hidden]> Matti

Narkia said:

It may be advisable to choose a vitamin E supplement which in addition to alpha-tocopherol
contains also gamma-tocopherol and other tocopherols, preferably also tocotrienols.

Blow some references which seem to suggest that gamma-tocopherol (and delta-tocopherol) should be
taken together with alpha-tocopherol:

For your convenience a few essential citations from selected abstracts:

Quoted message said:

1: Huang HY, Appel LJ. Supplementation of diets with alpha-tocopherol reduces serum concentrations
of gamma- and delta-tocopherol in humans. J Nutr. 2003 Oct;133(10):3137-40. PMID: 14519797
[PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve-
&db=PubMed&list_uids=14519797&dopt=Abstract>

"Despite promising evidence from in vitro experiments and observational studies, supplementation
of diets with alpha- tocopherol has not reduced the risk of cardiovascular disease and cancer in
most large-scale clinical trials. One plausible explanation is that the potential health
benefits of alpha-tocopherol supplements are offset by deleterious changes in the
bioavailability and/or bioactivity of other nutrients. ...

[...]

In view of the potential benefits of gamma- and delta- tocopherol, the efficacy of alpha-
tocopherol supplementation may be reduced due to decreases in serum gamma- and delta-tocopherol
levels. Additional research is clearly warranted."

Quoted message said:

2: Jiang Q, Ames BN. Gamma-tocopherol, but not alpha-tocopherol, decreases proinflammatory
eicosanoids and inflammation damage in rats. FASEB J. 2003 May;17(8):816-22. PMID: 12724340
[PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve-
&db=PubMed&list_uids=12724340&dopt=Abstract>

"... Here we report that in carrageenan-induced inflammation in male Wistar rats, administration
of gammaT (33 or 100 mg/kg) and gamma-CEHC (2 mg/pouch), but not alphaT (33 mg/kg),
significantly reduced PGE2 synthesis at the site of inflammation. gammaT, but not alphaT,
significantly inhibited the formation of leukotriene B4, a potent chemotactic agent synthesized
by the 5-lipoxygenase of neutrophils ...

[...]

Collectively, gammaT inhibits proinflammatory PGE2 and LTB4, decreases TNF-alpha, and attenuates
inflammation- mediated damage. These findings provide strong evidence that gammaT shows anti-
inflammatory activities in vivo that may be important for human disease prevention and therapy."

Quoted message said:

3: Jiang Q, Christen S, Shigenaga MK, Ames BN. gamma-tocopherol, the major form of vitamin E in
the US diet, deserves more attention. Am J Clin Nutr. 2001 Dec;74(6):714-22. Review. PMID:
11722951 [PubMed - indexed for MEDLINE] <URL:http://www.ajcn.org/cgi/content/full/74/6/714>

"... Both gamma-tocopherol and gamma-CEHC, but not alpha- tocopherol, inhibit cyclooxygenase
activity and, thus, possess antiinflammatory properties. Some human and animal studies indicate
that plasma concentrations of gamma- tocopherol are inversely associated with the incidence of
cardiovascular disease and prostate cancer. These distinguishing features of gamma-tocopherol
and its metabolite suggest that gamma-tocopherol may contribute significantly to human health in
ways not recognized previously. This possibility should be further evaluated, especially
considering that high doses of alpha-tocopherol deplete plasma and tissue gamma-tocopherol, in
contrast with supplementation with gamma-tocopherol, which increases both. ..."

--
Matti Narkia

MD/PhD said:

Quoted message said:

Blow some references which seem to suggest that gamma-tocopherol (and delta-tocopherol) should be
taken together with alpha-tocopherol:

Yes, you seem to be blowing, Matti.

You know, I have never killfiled anyone for excessive research posting until I met him/her.

Btw, what are him/hers qualifications anyway?

allthesky.comlunareclipse01a.htmlOpen ↗ Lift well, Eat less, Walk fast, Live long.

Mon, 05 Jan 2004 22:36:00 +0200 in article
<[email hidden]> Matti Narkia

Quoted message said:

Mon, 05 Jan 2004 22:33:39 +0200 in article <[email hidden]> Matti

Narkia said:

4: Jiang Q, Elson-Schwab I, Courtemanche C, Ames BN. gamma-tocopherol and its major metabolite,
in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial
cells. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11494-9. PMID: 11005841 [PubMed - indexed
for MEDLINE]

And the link is

<URL:http://www.pnas.org/cgi/content/full/94/7/3217>

It isn't ;-). Hope I get it right now:

<URL:http://www.pnas.org/cgi/content/full/97/21/11494>

--
Matti Narkia

There is some evidence that vitamin E may reduce blood pressure in people with mild hypertension,
who are not under anti-hypertensive medication.

See

Boshtam M, Rafiei M, Sadeghi K, Sarraf-Zadegan N. Vitamin E can reduce blood pressure in mild
hypertensives. Int J Vitam Nutr Res. 2002 Oct;72(5):309-14. PMID: 12463106 [PubMed - indexed for
MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=124631-
06&dopt=Abstract>

"... It is concluded that a vitamin E supplement of 200 IU/day can be effective in mild
hypertensive patients in the long term, probably due to nitric oxide, and improve their blood
pressure status. Therefore, vitamin E supplement could be recommended to such patients."

Brockes C, Buchli C, Locher R, Koch J, Vetter W. Vitamin E prevents extensive lipid peroxidation in
patients with hypertension. Br J Biomed Sci. 2003;60(1):5-8. PMID: 12680623 [PubMed - indexed for
MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=126806-
23&dopt=Abstract>

Vasdev S, Gill V, Parai S, Longerich L, Gadag V. Dietary vitamin E supplementation lowers blood
pressure in spontaneously hypertensive rats. Mol Cell Biochem. 2002 Sep;238(1-2):111-7. PMID:
12349898 [PubMed - indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retr-
ieve&db=PubMed&list_uids=12349898&dopt=Abstract>

Noguchi T, Ikeda K, Sasaki Y, Yamamoto J, Seki J, Yamagata K, Nara Y, Hara H, Kakuta H, Yamori Y.
Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone
spontaneously hypertensive rats. Hypertens Res. 2001 Nov;24(6):735-42. PMID: 11768736 [PubMed -
indexed for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list-
_uids=11768736&dopt=Abstract>

Pezeshk A, Derick Dalhouse A. Vitamin E, membrane fluidity, and blood pressure in hypertensive and
normotensive rats. Life Sci. 2000 Sep 1;67(15):1881-9. PMID: 11043610 [PubMed - indexed for
MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11043-
610&dopt=Abstract>

On the other hand in the study

Palumbo G, Avanzini F, Alli C, Roncaglioni MC, Ronchi E, Cristofari M, Capra A, Rossi S, Nosotti
L, Costantini C, Cavalera C. Effects of vitamin E on clinic and ambulatory blood pressure in
treated hypertensive patients. Collaborative Group of the Primary Prevention Project (PPP)--
Hypertension study. Am J Hypertens. 2000 May;13(5 Pt 1):564-7. PMID: 10826412 [PubMed - indexed
for MEDLINE] <URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=-
10826412&dopt=Abstract>

vitamin E (alpha-tocopherol) failed to have clinically relevant effect on blood pressure in
hypertensive patients already under controlled treatment.

--
Matti Narkia

On Mon, 5 Jan 2004 18:32:34 -0500, Totality of Lunar Mu_n Eclipsed
wrote
(in message <[email hidden]>😉:

Quoted message said:

MD/PhD said:

Quoted message said:

Blow some references which seem to suggest that gamma-tocopherol (and delta-tocopherol) should
be taken together with alpha-tocopherol:

Yes, you seem to be blowing, Matti.

You know, I have never killfiled anyone for excessive research posting until I met him/her.

Btw, what are him/hers qualifications anyway?

First, and foremost, he's not you. Second, he's not Chung.

Sounds like pretty good qualifications to me :-)

--
Steve

Weeding the Lord's Vineyards Since 2003

Totality of Lunar Mu_n Eclipsed said:

MD/PhD said:

Quoted message said:

Blow some references which seem to suggest that gamma-tocopherol (and delta-tocopherol) should be
taken together with alpha-tocopherol:

Yes, you seem to be blowing, Matti.

See Chung smear. See his careful, scientific rejoinder. See his well-reasoned reply. See his
emptiness.

Quoted message said:

You know, I have never killfiled anyone for excessive research posting until I met him/her.

"Excessive research posting." What a heavyweight is M_uncher. Too much science is a group whose name
includes the word "science." It's that gnat-like attention span again.

Quoted message said:

Btw, what are him/hers qualifications anyway?

Matti's qualifications aren't material to Chung's dismal showing and your sad comment that you're
getting too much information to handle. Deal with the information. You know, that which you can not
provide...

Oh, and what are your qualifications? Looks like yours don't include much science. "It's too big for
little me. I bet Matti's anti-Christian because he gives me more info than I can handle," whines the
overwhelmed M_ucus.

Pastorio

Thorsten Schier <[email hidden]> wrote in message news:<[email hidden]>...

Quoted message said:

francispoon schrieb:

Quoted message said:

I was advised by my doctor that 50 mg a day of this Vitamin E is better than an aspirin a day.

Is there any truth there?

snipped...

Quoted message said:

According to the Health Professionals Follow Up Study and the Nurses' Health Study 50 mg is
probably not enough to protect from heart disease. 200 mg seem to be a reasonable amount to take.

Agreed.

Quoted message said:

If you decide to take a supplement, make sure that the vitamin E comes from a natural sources.
Synthetic vitamin E is less effective and is probably a waste of money.

Seen this somewhere before and it is worth noting. THX

Quoted message said:

Bottomline:

Research suggests that vitamin E can reduce the risk of coronary heart disease, at least in
primary prevention. So does aspirin. However, as both probably don't work by the same mechanism,
there seems to be no reason why someone should not take aspirin when they take vitamin E. So you
might want to consider taking both.

I read somewhere in Google that vitamin E and aspirin should not be taken at the same time for
reasons which i don't understand.

FP
=====================================

Quoted message said:

Thorsten

francispoon schrieb:

Quoted message said:

Thorsten Schier <[email hidden]> wrote in message news:<[email hidden]>...

Quoted message said:

francispoon schrieb:

Quoted message said:

I was advised by my doctor that 50 mg a day of this Vitamin E is better than an aspirin a day.

Is there any truth there?

snipped...

Quoted message said:

According to the Health Professionals Follow Up Study and the Nurses' Health Study 50 mg
is probably not enough to protect from heart disease. 200 mg seem to be a reasonable
amount to take.

Agreed.

Quoted message said:

If you decide to take a supplement, make sure that the vitamin E comes from a natural sources.
Synthetic vitamin E is less effective and is probably a waste of money.

Seen this somewhere before and it is worth noting. THX

Quoted message said:

Bottomline:

Research suggests that vitamin E can reduce the risk of coronary heart disease, at least in
primary prevention. So does aspirin. However, as both probably don't work by the same mechanism,
there seems to be no reason why someone should not take aspirin when they take vitamin E. So you
might want to consider taking both.

I read somewhere in Google that vitamin E and aspirin should not be taken at the same time for
reasons which i don't understand.

Vitamin E can might enhance the antiplatlet effect of aspirin. While this would perhaps offer better
protection against cardiovascular events, it might also increase the risk of hemorrhagic strokes. So
if want to take both at the same time you should consult a doctor first.

See:

ncbi.nlm.nih.govquery.fcgiOpen ↗
t=Abstract

and:

google.desearchOpen ↗

Thorsten

--
"Nothing in biology makes sense, except in the light of evolution"

(Theodosius Dobzhansky)