Disc brake recommendation

FWIW ...

[INDENT]I would opt for the TRP Spyre because I thnk it is the one which is designed to be used with ROAD levers ...

[INDENT]It should be both easy to set up AND (especially) maintain ...
[/INDENT]
BUT, I'm going to say that I think you may want the TRP Spyke which is designed to be used with most mechanical MTB levers which would otherwise typically be used with V-brakes.

PLEASE NOTE: I could have the particular calipers mismatched with the particular mechanical levers in MY mind & the Spyke may be the one designed for Road levers.[/INDENT]

BTW. I think that if your fork accommodates a 160mm rotor, then that is what you want to use ...

[INDENT]140mm rotors are probably better suited for the rear ...

If weight is the issue, then use CENTERLOCK hubs-and-rotors.[/INDENT]

I have TRP Spyre on my gravel grinder. They are quality. Easy to work on. Dual sided caliper is great/smart. Stop on a dime.

The Spyres are easy to install and easy to keep in good order. I have read that the pad adjustment screws back out over time, but I don't use them - I've taken care to centre the calipers carefully and then just use the barrel adjuster as the pads wear. They stop well, but which disc brake doesn't?