General fitness, health and nutrition · Public discussion

Plasmid Evolution

Started by Pedro · · Last activity · 2 posts · 481 views

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General fitness, health and nutrition
Published
30 December 2003
Last activity
30 December 2003
Original author
Pedro
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  1. Plasmids generally contain genes that confer a selective advantage to their bacterial hosts through
    antibiotic resistance or virulence factors. However, despite these advantages,plasmid transfer rates
    are normaly very low due to segregation and fitness costs to their hosts; too low to account for
    their widespread existence.

    I would like to hear from anyone who has any insight into this matter. There are some reported cases
    where evolved plasmids introduced into bacteria have increased their fitness almost two-fold.

    Any information would be much apreciated

    Best regards, Pedro Vale

  2. "Pedro" <[email hidden]> wrote in message
    "]news:[email hidden]...

    Quoted message said:

    Plasmids generally contain genes that confer a selective


    advantage to

    Quoted message said:

    their bacterial hosts through antibiotic resistance or


    virulence

    Quoted message said:

    factors. However, despite these advantages,plasmid


    transfer rates are

    Quoted message said:

    normaly very low due to segregation and fitness costs to


    their hosts;

    Quoted message said:

    too low to account for their widespread existence.

    What does "widespread" mean here? Is there really any objective measure of existence relative to
    other lifeforms? This sounds like a very subjective thing wrt prerequisite characteristics/
    conditions for specific examples (i.e., is this a semantics problem?) ...tonyC <non-biologist>

    Quoted message said:

    I would like to hear from anyone who has any insight into


    this matter.

    Quoted message said:

    There are some reported cases where evolved plasmids


    introduced into

    Quoted message said:

    bacteria have increased their fitness almost two-fold.

    Any information would be much apreciated

    Best regards, Pedro Vale

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