wheel help!

Just shooting from the hip I'm going to say you're too heavy for that wheel, the wheel is of poor stiffness or failing, and/or spoke tension could possibly be adjusted. There may even be very minimal clearance between the stays, depending on the frame/wheel/tires.

If this is a new development on a wheel you havent had any issues with climbing before, then its spoke tension or rim-related. If this is an issue with a new wheel, its more likely a stiffness or weight issue. Kind of thing where if we dont know anything, you'd be best served to take it to your LBS and describe the issue. If they have an experienced wheel builder there they should be able to figure out the problem.

What kind of wheel? What do you weigh? How long have you had it? Is it a new issue on a old wheel or an issue with a brand new wheel? If you supply more info maybe someone can help more specifically.

Hope you get it cleared up without too much trouble.

Check a few obvious things first: push the wheel laterally back-and-forth at the brakes and chainstays to see what's moving and where it's rubbing. Could be the axle is loose in the dropouts due to a loose or defective skewer, a dropout joining screw is broken, the wheel is not correctly mounted (centered) in the dropouts, the wheel isn't properly dished, or the spokes have gone slack.

If you confirm that the cause is the wheel itself and not the installation, you can take the wheel to an LBS for retensioning or rebuilding. Actually, even easier is to just take the bike in. An experienced mechanic should be able to diagnose the problem quickly and maybe even fix it at little or no cost.