<<snip>>
iron may increase the risk of infection by invasive diarrheal
pathogens
<<snip>>
http://www.apria.com/resources/1,2725,494-637115-3,00.html
Study results from Harvard University, Department of Nutrition update
understanding of diarrhea in children
Scientists discuss in "The comparative impact of iron, the B-complex
vitamins, vitamins C and E, and selenium on diarrheal pathogen
outcomes relative to the impact produced by vitamin A and zinc" new
findings in diarrhea. According to a study from the United States,
"Micronutrient supplementation offers one of the most cost-effective
means of improving the health and survival of children in developing
countries. However, the effects of supplementation with single
micronutrients on diarrhea are not always consistent, and
supplementation with multi-micronutrient supplements can have negative
effects."
"These inconsistencies may result from the failure to consider the
diverse etiological agents that cause diarrhea and the unique effects
each micronutrient has on the immune response to each of these agents.
This review examines the separate effects that supplementation with
the B-complex vitamins, vitamin C, vitamin E, selenium, and iron have
on diarrheal disease-related outcomes. Supplementation with iron may
increase the risk of infection by invasive diarrheal pathogens, while
supplementation with the remaining micronutrients may reduce this
risk. These differences may be due to distinct regulatory effects each
micronutrient has on the pathogen-specific immune response, as well as
on the virulence of specific pathogens. The findings of these studies
suggest that micronutrient supplementation of children must take into
account the pathogens prevalent within communities as reflected by
their diarrheal disease burdens," wrote K.Z. Long and colleagues,
Harvard University, Department of Nutrition.
The researchers concluded: "The effectiveness of combining multiple
micronutrients into one supplement must also be reconsidered."
Long and colleagues published their study in Nutrition Reviews (The
comparative impact of iron, the B-complex vitamins, vitamins C and E,
and selenium on diarrheal pathogen outcomes relative to the impact
produced by vitamin A and zinc. Nutrition Reviews, 2007;65(5):
218-32).
For more information, contact K.Z. Long, Harvard School of Public
Health, Dept. of Nutrition, Harvard School of Public Health, 1663
Tremont Street, Boston, MA 02115 USA.
Publisher contact information for the journal Nutrition Reviews is:
International Life Sciences Institute North America, One Thomas
Circle, N W, 9TH Floor, Washington, DC 20005, USA.
Keywords: United States, Boston, Alternative Medicine, Antiacne,
Diarrhea, Gastroenterology, Therapy, Treatment, Vitamin A, Vitamins
(Vitamin A).
This article was prepared by Drug Law Week editors from staff and
other reports. Copyright 2007, Drug Law Week via NewsRx.com.
To see more of the NewsRx.com, or to subscribe, go to http://www.newsrx.com
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