Antioxidants Don't Cut Heart Disease Risk: Study
By Keith Mulvihill and Karla Gale Friday, June 13, 2003
New York (Reuters Health) - Antioxidants such as beta carotene and vitamin E don't cut the risk of
dying from heart disease, and beta carotene may even slightly increase the risk, according to a new
analysis of studies conducted in the past.
As a result, researchers at the Cleveland Clinic Foundation said the use of supplements containing
beta carotene and vitamin A (a beta carotene metabolite) should be actively discouraged and that
clinical studies using the antioxidant be discontinued.
In addition, they also discourage similar investigations involving vitamin E for heart disease
treatment or prevention.
But the conclusions of the new study sparked criticism from one expert.
The conclusions are "unwarranted and very surprising," said Dr. Jeffrey Blumberg of Tufts University
in Boston, Massachusetts, in an interview with Reuters Health.
"No new research has been conducted and this is why their conclusions are so surprising," added
Blumberg, who is an antioxidant researcher.
In the study, Dr. Deepak P. Vivekananthan and associates reviewed seven previously published trials
of vitamin E treatment and eight trials of beta carotene treatment, according to the report
published in the June 14th issue of The Lancet. All of the trials included at least 1,000 patients
and were trials in which patients were randomly assigned to take the supplements or a "control"
treatment. . . . [...] This is only an excerpt -- read the complete news at:
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