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Atopic dermatitis

Started by Doe · · Last activity · 4 posts · 693 views

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General fitness, health and nutrition
Published
26 October 2003
Last activity
27 October 2003
Original author
Doe
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  1. Original post
    Doe
    Archived post
    #1

    Dermatology. 2003;207(3):261-4. Related Articles, Links

    High iron and low ascorbic Acid concentrations in the dermis of atopic dermatitis patients.

    Leveque N, Robin S, Muret P, Mac-Mary S, Makki S, Humbert P.

    Laboratoire d'Ingenierie et de Biologie Cutanees, Faculte de Medecine et de Pharmacie, Place Saint
    Jacques, Besancon, France.

    BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease in which reactive oxygen
    species (ROS) may be involved. Iron catalyses ROS formation and ascorbic acid (AA) scavenges these
    species. OBJECTIVE: The aim of this work was to determine iron and AA levels in AD patients' dermis
    and to compare their concentrations with those of healthy volunteers' dermis. METHODS: Five AD
    patients and 5 healthy subjects (controls) were enrolled in this study. Iron and AA were collected
    from human dermis by microdialysis and assessed by atomic absorption spectrometry and gas
    chromatography-mass spectrometry, respectively. RESULTS: The AD dermis demonstrated higher iron
    concentrations
    (44.3 +/- 4.6 mug/l) compared to controls (21.8 +/- 1.2 mug/l) as well as a significantly lower
    concentration of AA (46.7 +/- 0.6 vs. 176.8 +/- 14.5 mug/ml, respectively). CONCLUSION: These
    results suggest that iron and AA dermis levels could be indicators of inflammatory tissues and
    might be implicated in dermatological diseases such as AD. Copyright 2003 S. Karger AG, Basel

    PMID: 14571067 [PubMed - in process]

    --------------------------------------------------------------------------
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  2. Jeff
    Archived post
    #2

    This is a reflection of what is already known: In areas where this is inflammation, iron is used to
    make free radicals and vitamin C is used to help keep them in check. It does not demonstrate that
    vitamin C helps inflammation or atopic dermitis or that people with this have a problem with too
    much iron or that the iron plays a causal role at all.

    Jeff

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  3. Doe
    Archived post
    #3
    Quoted message said:

    Subject: Re: Atopic dermatitis From: "Jeff" [email hidden] Date: 10/26/2003 3:55 PM
    Mountain Standard Time Message-id: <[email hidden]>

    This is a reflection of what is already known: In areas where this is inflammation, iron is used to
    make free radicals and vitamin C is used to help keep them in check. It does not demonstrate that
    vitamin C helps inflammation or atopic dermitis or that people with this have a problem with too
    much iron or that the iron plays a causal role at all.

    <<snip>> CONCLUSION: These results suggest that iron and AA dermis levels could be indicators of
    inflammatory tissues and might be implicated in dermatological diseases such as AD <<snip>>

    I think I will stick with what the researchers believe .. not what YOU believe ..

    You have demonstrated your abilities and were found .. wanting ..

    Who loves ya. Tom Jesus Was A Vegetarian! jesuswasavegetarian.7h.comjesuswasavegetarian.7h.com Man Is A Herbivore!
    pages.ivillage.commanisaherbivore DEAD PEOPLE WALKING
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  4. Jeff
    Archived post
    #4

    "doe" <[email hidden]> wrote in message "]news:[email hidden]...

    Quoted message said:
    Quoted message said:

    Subject: Re: Atopic dermatitis From: "Jeff" [email hidden] Date: 10/26/2003 3:55 PM
    Mountain Standard Time Message-id: <[email hidden]>

    This is a reflection of what is already known: In areas where this is inflammation, iron is used
    to make free radicals and vitamin C is used to help keep them in check. It does not demonstrate
    that vitamin C helps inflammation or atopic dermitis or that people with this have a problem


    with

    Quoted message said:
    Quoted message said:

    too much iron or that the iron plays a causal role at all.

    <<snip>> CONCLUSION: These results suggest that iron and AA dermis levels could be indicators of
    inflammatory tissues and might be implicated in dermatological diseases such as AD <<snip>>

    I think I will stick with what the researchers believe .. not what YOU


    believe

    Actually, I will stick to what the researchers report. I don't read minds, so I don't know what they
    believe. They report that iron "could be" an indicator of inflammatory tissues. Just like I said.

    Quoted message said:


    You have demonstrated your abilities and were found .. wanting ..

    You have demonstrated you abilities to undestand scientific material and they have been
    found absent.

    Jeff

    Report

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