Physicians and niacin

Preston,

An FDA approved product, Niaspan, is a slow release niacin with much
less flushing. See http://www.niaspan.com/

[email hidden] (Preston Rich) wrote in message news:<[email hidden]>...

Quoted message said:

Interesting thread w/physicians discussing niacin supplementation at:

http:[email hidden]@.eeb95ee

On 31 Oct 2003 12:58:51 -0800, Brad Sheppard <[email hidden]>

Quoted message said:

Preston,

An FDA approved product, Niaspan, is a slow release niacin with much
less flushing. See http://www.niaspan.com/

[email hidden] (Preston Rich) wrote in message
news:<[email hidden]>...

Quoted message said:

Interesting thread w/physicians discussing niacin supplementation at:

http:[email hidden]@.eeb95ee

I also recomend taking plain, generic niacin right before bedtime with
aspirin. Aspirin can help stop the flush, and if flusing occurs, often
people sleep right through it. The generic is less expensive than the slow
release preparations but still a very helpful preparation for some people.

--
~~~
Patrick Blanchard, M.D., A.B.F.P.
Board Certified in Family Practice

"Patrick Blanchard, M.D." <[email hidden]> wrote in message
news:[email hidden]...

Quoted message said:

On 31 Oct 2003 12:58:51 -0800, Brad Sheppard <[email hidden]>

Quoted message said:

Preston,

An FDA approved product, Niaspan, is a slow release niacin with much
less flushing. See http://www.niaspan.com/

[email hidden] (Preston Rich) wrote in message
news:<[email hidden]>...

Quoted message said:

Interesting thread w/physicians discussing niacin supplementation at:

http:[email hidden]@.eeb95ee

I also recomend taking plain, generic niacin right before bedtime with
aspirin. Aspirin can help stop the flush, and if flusing occurs, often
people sleep right through it. The generic is less expensive than the slow
release preparations but still a very helpful preparation for some people.

--
~~~
Patrick Blanchard, M.D., A.B.F.P.
Board Certified in Family Practice

What dose do you think is best? I take a very small dose (50 mg) because I
also take Lipitor and I've read the combination can increase the chances of
muscle problems that sometimes occurs with Lipitor.

Bill

It seems to me I heard somewhere that Bill wrote in article
<[email hidden]>:

Quoted message said:

"Patrick Blanchard, M.D." <[email hidden]> wrote in message
news:[email hidden]...

Quoted message said:

On 31 Oct 2003 12:58:51 -0800, Brad Sheppard <[email hidden]>
wrote:

Quoted message said:

Quoted message said:

Quoted message said:

An FDA approved product, Niaspan, is a slow release niacin with much
less flushing. See http://www.niaspan.com/

Quoted message said:

Quoted message said:

Quoted message said:

[email hidden] (Preston Rich) wrote in message
news:<[email hidden]>...
> Interesting thread w/physicians discussing niacin supplementation at:

Quoted message said:

Quoted message said:

Quoted message said:

> http:[email hidden]@.eeb95ee

Quoted message said:

Quoted message said:

I also recomend taking plain, generic niacin right before bedtime with
aspirin. Aspirin can help stop the flush, and if flusing occurs, often
people sleep right through it. The generic is less expensive than the slow
release preparations but still a very helpful preparation for some people.

Quoted message said:

What dose do you think is best? I take a very small dose (50 mg) because I
also take Lipitor and I've read the combination can increase the chances of
muscle problems that sometimes occurs with Lipitor.

An amicus curiae note: I've been on niacin since my angioplasty five
years ago, and on Lipitor for the last four of those years. Niacin was
1000mg until earlier this year, and 500mg since; Lipitor has moved up
from 20mg to a current 80mg. No muscular involvement that I can
attribute to either medication or to the combination.

I very much subscribe to the doctrine of individual variations, so this
is not a recommendation for your own regiment.
--
Don
[email hidden]

M.D. said:

I also recomend taking plain, generic niacin right before bedtime with
aspirin. Aspirin can help stop the flush, and if flusing occurs, often
people sleep right through it.

This appears to be a poor tradeoff in the timing of taking of ASA. I
would think taking it first thing in the morning, to address its more
important properties regarding MIs.

http://antwrp.gsfc.nasa.gov/apod/ap970827.html
Lift well, Eat less, Walk fast, Live long.

Partial Eclipse Of The Mu_n said:

M.D. said:

I also recomend taking plain, generic niacin right before bedtime with
aspirin. Aspirin can help stop the flush, and if flusing occurs, often
people sleep right through it.

This appears to be a poor tradeoff in the timing of taking of ASA. I
would think taking it first thing in the morning, to address its more
important properties regarding MIs.

Sounds like you're practicing Mu_dicine. Which med school did you get
your MD from?

Pastorio

Partial Eclipse Of The Mu_n said:

M.D. said:

I also recomend taking plain, generic niacin right before bedtime with
aspirin. Aspirin can help stop the flush, and if flusing occurs, often
people sleep right through it.

This appears to be a poor tradeoff in the timing of taking of ASA. I
would think taking it first thing in the morning, to address its more
important properties regarding MIs.

I'm not a doctor, but I previously asked here about ASA's mode of
action and pharmacokinetics. Apparently the scientific answer is that
ASA irrerversibly alters the platelet function a bit to stick less and
that they have a 2-3 week lifespan. So for the clinical effect it
probably doesn't matter exactly when you take the aspirin as long as
you keep it up consistently.

Quoted message said:

http://antwrp.gsfc.nasa.gov/apod/ap970827.html
Lift well, Eat less, Walk fast, Live long.

--
---------------------------------------------
Matthew Kennel, [email hidden]
Institute For Nonlinear Science, UC San Diego
---------------------------------------------

Dr Chaos said:

I'm not a doctor, but I previously asked here about ASA's mode of
action and pharmacokinetics. Apparently the scientific answer is that
ASA irrerversibly alters the platelet function a bit to stick less and
that they have a 2-3 week lifespan. So for the clinical effect it
probably doesn't matter exactly when you take the aspirin as long as
you keep it up consistently.

There would still be low and high dosages in circulation and residing
in tissues. That cannot be a constant unless ASA is somehow regulated
to a constant.

If this is true, then it would appear to be preferable to be refilling
the dosage at the most opportune time, in the morning when most MI's
occur.

http://antwrp.gsfc.nasa.gov/apod/ap970827.html
Lift well, Eat less, Walk fast, Live long.

Dr Chaos said:

Partial Eclipse Of The Mu_n said:

M.D. said:

I also recomend taking plain, generic niacin right before bedtime with
aspirin. Aspirin can help stop the flush, and if flusing occurs, often
people sleep right through it.

This appears to be a poor tradeoff in the timing of taking of ASA. I
would think taking it first thing in the morning, to address its more
important properties regarding MIs.

I'm not a doctor, but I previously asked here about ASA's mode of
action and pharmacokinetics. Apparently the scientific answer is that
ASA irrerversibly alters the platelet function a bit to stick less and
that they have a 2-3 week lifespan. So for the clinical effect it
probably doesn't matter exactly when you take the aspirin as long as
you keep it up consistently.

Correct.

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
http://www.heartmdphd.com/

I've taken 1.5 grams of generic niacin twice a day for about three
months. It took about three weeks to get up to the 1.5-gram-at-once
without uncomfortable flushing, and even now, I take the dose after
food. There's been no abnormal liver enzyme activity and my HDL has
increased 20 per cent, to 1.64 from 1.36.

Paul

MD/PhD said:

Dr Chaos said:

Partial Eclipse Of The Mu_n said:

On Fri, 31 Oct 2003 15:16:42 -0600, "Patrick Blanchard, M.D."
<[email hidden]> wrote:

>
>I also recomend taking plain, generic niacin right before bedtime with
>aspirin. Aspirin can help stop the flush, and if flusing occurs, often
>people sleep right through it.

This appears to be a poor tradeoff in the timing of taking of ASA. I
would think taking it first thing in the morning, to address its more
important properties regarding MIs.

I'm not a doctor, but I previously asked here about ASA's mode of
action and pharmacokinetics. Apparently the scientific answer is that
ASA irrerversibly alters the platelet function a bit to stick less and
that they have a 2-3 week lifespan. So for the clinical effect it
probably doesn't matter exactly when you take the aspirin as long as
you keep it up consistently.

Correct.

Dear Friends,

(I decided to visit after a few months sulking 🙁( )

Re: niacin and flushing

For the last year or so, I've been taking a 500mg niacin pill twice per
day).

This is a *flushfree* niacin !!

I mentioned it on this ng months ago. Are you *all* that inattentive ???

BTW, the niacin is put out by the QUEST Company and is annoted as
'Flush-Free' (as a trademark).

I'll seeya in another few months.

-Mel Smith