General fitness, health and nutrition · Public discussion

Re: Will the real "essential fatty acid" hypothesis please stand up!

Started by MMu · · Last activity · 1 post · 243 views

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General fitness, health and nutrition
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7 November 2005
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MMu
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  1. "montygram" <[email hidden]> schrieb im Newsbeitrag
    news:[email hidden]...

    [snipped pointless smalltalk]

    Quoted message said:

    I have tried to construct an "essential fatty acid" (EFA)
    hypothesis, since those who enjoy attacking the basic, scientific
    points I make refuse to do so. At least two posters have actually said
    that omega 3 and 6 polyunsaturated fatty acids (PUFAs) are
    "essential" because the body cannot make them, as if any substance
    the body cannot make is "essential." Perhaps they feel that
    cyanide is essential, since the body cannot make it either.

    Cyanide is not a nutrient
    Cyanide does not fulfill a physiological function in vivo (when one
    differentiates cyanide from -cn groups that is)

    PUFA's do.

    Quoted message said:

    If they
    decide to act upon this, at least the rest of us will no longer have to
    read their absurd posts and witness their dodging of basic scientific
    methodology all the time.

    you do not have a trace of an idea of scientific methodology.
    you never did any practical research work in a lab nor did you even publish
    a single biochemical paper.
    you think biochemical research on hundreds of animals over their lifetime
    period can be accomplished with about 100 bucks.

    the dodging part is your métier... how often have you been confronted with
    criticism on your theory and how often did you just ignore the tons of
    studies and remarks.

    Quoted message said:

    I now see why they refuse to respond to my request to state a basic
    scientific hypothesis for "EFAs"

    Maybe you should make a habit of reading the replies to your posts?
    Many times all the arguments have been stated.. just do a search on
    montygram and read the replies again.
    Nobody feels the need to jump upon the band wagon for the 100th time just
    because you are ignorant to the evidence presented to you.

    Quoted message said:

    Moreover, omega 3
    and/or 6 PUFAs would have to be compared to the omega 9 PUFA made by
    humans, the Mead acid, and this has never been done, as far as I have
    been able to determine (after years of researching it).

    Is there a significant content of mead acid in any food you know?
    I not, why should it be used as a control?

    Quoted message said:

    Moreover, it
    could be a matter of high quality protein intake or some other obvious
    factor, and all would have to be controlled for in experiments.

    And it is controlled for. It didn't change the facts however.

    Quoted message said:

    Instead, researchers usually have compared a totally fat free diet,
    which no animal used in the experiments eats in its natural
    environment, against a fat source that contains all classes of fatty
    acids.

    Nonsense.
    There is a lot of research where animals got fed either w3/w6 or non w3/w6
    fat sources.
    The articles have been posted numerous times.

    Quoted message said:

    They talk of "dry skin" and such as
    well, but as I've learned, when you are "deficient" in the
    "EFAs" you may need to drink more, and then this is not a problem,
    so we'd need to know if the animals were given enough water.

    You didn't proove that you are deficient until now.

    Quoted message said:

    The evidence that omega 3 and 6 PUFAs are very dangerous is
    overwhelming, so anyone who wants to posit that they are
    "essential" had better have some very strong evidence that this is
    the case.

    The evidence in fact is so "overwhelming" that people in coutries who
    consume lots of fish oil (japan/okinawa) live the longest of all the rest of
    the world!

    I wish all "very dangerous" substances would be like that.

    Quoted message said:

    In actuality, the evidence is either terribly flawed (as
    mentioned above and as examined in other posts) or is irrelevant.

    Which is a very easy and convenient way to deal with problems in your theory
    isn't it?
    If the study presented does not fit in your theory its "terribly flawed".
    If it does not fit it your theory but its overwhelmingly backed up by tons
    of evidence its "irrelevant".

    Interesting approach to "scienfic method".

    Quoted message said:

    A common and comprehensive book on nutrition today is "Perspectives
    in Nutrition" by Gordon Wardlaw (see pages 120 and 135 of the fourth
    edition). The author claims that one needs at least "1 tablespoon of
    polyunsaturated plant oil a day," which he claims is acceptable even
    on a very low fat diet.

    The book is completely irrelevant-
    There are books on anything with any topic and comclusion you like.

    Science, however, is NOT based on such books- science is based on peer
    reviewed, controlled and published experiments.

    Quoted message said:

    One individual said that he didn't want to
    subject the rats to such a horrible diet - the kind that I have been
    eating for about 4 years now, with no "deficiency symptoms" and
    many benefits. Isn't he a great guy? Perhaps we should call him the
    "rat lover," sparing the cute little rats the terrible fate of a
    long life lived in great health. Presumably, this rat lover man thinks
    it's better if the rats were instead used in the more common kinds of
    experiments, where they would be given cancer and then their heads
    would be chopped off in a few weeks, at most.

    Perhaps this rat-lover man thinks you should just make a blood test insted
    of letting 100 rats die?
    Since you claim to be deficient it would be interesting to check that with a
    SCIENTIFIC method.

    Quoted message said:

    Oncogene. 2004 Dec 9;23(57):9259-68.
    Role of the BLT2, a leukotriene B4 receptor, in Ras transformation.

    Quoted message said:

    Clin Cancer Res. 2004 Oct 1;10(19):6703-9.
    Overexpression of 5-lipoxygenase in rat and human esophageal
    adenocarcinoma and inhibitory effects of zileuton and celecoxib on
    carcinogenesis.

    Quoted message said:

    Blood. 2005 Feb 1;105(3):1274-9. Epub 2004 Sep 28. Related Articles,
    Links
    Leukotriene B4 plays a pivotal role in CD40-dependent activation of
    chronic B lymphocytic leukemia cells.

    Quoted message said:

    There are about 250 of these just on the LTB4 connection to cancer at

    What these articles show is that a metabolite of AA plays a role in cancer-
    apparently as a signaling molecule.
    Does that mean that AA causes cancer?
    No.

    Vitamins play a role in cancer, they even feed cancer.. that doesn't mean
    vitamins are bad- even though a tumor can't grow if there are no vitamins
    present.

    Signaling molecules play a large part in cancer.. the Hif - group for a
    prominent example- but they play roles in other areas as well where they are
    essential for survival of cells.

    Your logic is therefore rather shallow.

    Quoted message said:

    Interestingly, some authors blame the toxic effects of cod liver oil
    supplmentation, which was popular several decades ago, on the vitamin A
    and D it contains, yet there are plenty of people who have been
    consuming megadoses of vitamin supplements since the 1960s, and yet the
    toxicity of all the supplements combined (with the few rare exceptions
    that are totally unrelated to A and D, such as the tryptophan deaths)
    appears to be nearly nonexistent.

    Please quote the reference to that.

    Quoted message said:

    Rather, taking large doses of fish
    oil, a substance that will generate huge amounts of free radicals, is
    undeniably highly toxic, and I've proposed on point experiments,
    comparing rats/mice large amounts of fish oil or fresh coconut oil, but
    of course, nobody is interested, even though I will pay for all
    expenses if the fish oil group lives longer.

    Such experiments have already been done, published and cited to you.

    Quoted message said:

    The activity damages or destroys vital biomolecules,
    switches biochemical pathways on that should be off (and vice versa),
    and can then lead to tissue or organ damage or severe dysfunction.

    What an amazing nonsense.
    No wonder authors of studies don't reply to your emails when you say things
    like that.

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