Longevity techniques?

OmManiPadmeOmelet said:

Eat a good diet,
exercise regularly,
make sure you get enough daily vitamins and minerals,
get plenty of sleep and avoid stress,

and take DHEA, Melatonin and HGH if you can afford it.

Cheers!

Bored on Sat night Om? :-)

Here is a new one for you! PMID: 15919742 -

"administration of GH is often advocated as an "anti-aging" therapy.
In sharp contrast ... GH deficiency, GH resistance, and reduced IGF-I
signaling in mice are associated with symptoms of delayed aging and
markedly extended longevity. Although most normal mice
die at approximately 2 yr of age, hypopituitary and GH-resistant
mutants often survive beyond the age of 3 yr and occasionally past the
age of 4 yr, i.e. outside the range encountered in various laboratory
strains of this species."

When will I convince you?
HGH is a scam.

In article <[email hidden]>,

DZ said:

OmManiPadmeOmelet said:

Eat a good diet,
exercise regularly,
make sure you get enough daily vitamins and minerals,
get plenty of sleep and avoid stress,

and take DHEA, Melatonin and HGH if you can afford it.

Cheers!

Bored on Sat night Om? :-)

Yes, actually. ;-)
I'm going back and forth between the computer and the kitchen.
I'm making pork and shrimp fried rice. Done correctly, it's done in
steps so take time.

Quoted message said:

Here is a new one for you! PMID: 15919742 -

"administration of GH is often advocated as an "anti-aging" therapy.
In sharp contrast ... GH deficiency, GH resistance, and reduced IGF-I
signaling in mice are associated with symptoms of delayed aging and
markedly extended longevity. Although most normal mice
die at approximately 2 yr of age, hypopituitary and GH-resistant
mutants often survive beyond the age of 3 yr and occasionally past the
age of 4 yr, i.e. outside the range encountered in various laboratory
strains of this species."

When will I convince you?
HGH is a scam.

No, but only because I've seen what it's done for my 73 year old father.

We give him 1 IU twice per week and his "geriatric" skin no longer
suffers from echymosis with every cut and scrape, and it's getting
thicker instead of paper thin. His memory, mood/attitude, energy levels
and libido have all improved.

And it's the _only_ change we have made.

HGH is not a scam.

YMMV.

Cheers!
--
Om.

"My mother never saw the irony in calling me a son-of-a-[censored]." -Jack Nicholson

In article <[email hidden]>,

DZ said:

OmManiPadmeOmelet said:

Eat a good diet,
exercise regularly,
make sure you get enough daily vitamins and minerals,
get plenty of sleep and avoid stress,

and take DHEA, Melatonin and HGH if you can afford it.

Cheers!

Bored on Sat night Om? :-)

Here is a new one for you! PMID: 15919742 -

"administration of GH is often advocated as an "anti-aging" therapy.
In sharp contrast ... GH deficiency, GH resistance, and reduced IGF-I
signaling in mice are associated with symptoms of delayed aging and
markedly extended longevity. Although most normal mice
die at approximately 2 yr of age, hypopituitary and GH-resistant
mutants often survive beyond the age of 3 yr and occasionally past the
age of 4 yr, i.e. outside the range encountered in various laboratory
strains of this species."

When will I convince you?
HGH is a scam.

Ps, humans are not genetically line bred mice......
--
Om.

"My mother never saw the irony in calling me a son-of-a-[censored]." -Jack Nicholson

OmManiPadmeOmelet said:

DZ said:

OmManiPadmeOmelet said:

Eat a good diet,
exercise regularly,
make sure you get enough daily vitamins and minerals,
get plenty of sleep and avoid stress,

and take DHEA, Melatonin and HGH if you can afford it.

Cheers!

Bored on Sat night Om? :-)

Yes, actually. ;-)
I'm going back and forth between the computer and the kitchen.
I'm making pork and shrimp fried rice. Done correctly, it's done in
steps so take time.

Quoted message said:

Here is a new one for you! PMID: 15919742 -

"administration of GH is often advocated as an "anti-aging" therapy.
In sharp contrast ... GH deficiency, GH resistance, and reduced IGF-I
signaling in mice are associated with symptoms of delayed aging and
markedly extended longevity. Although most normal mice
die at approximately 2 yr of age, hypopituitary and GH-resistant
mutants often survive beyond the age of 3 yr and occasionally past the
age of 4 yr, i.e. outside the range encountered in various laboratory
strains of this species."

When will I convince you?
HGH is a scam.

No, but only because I've seen what it's done for my 73 year old father.

Improved quality of life of an ill old person?

So does morphine.

There is absolutely no evidence HGH has positive effect on longevity
and plenty of evidence it does the reverse.

Yeah, we're not mice is ALWAYS a good argument.

In article <[email hidden]>,

DZ said:

OmManiPadmeOmelet said:

DZ said:

OmManiPadmeOmelet <[email hidden]> wrote:
> Eat a good diet,
> exercise regularly,
> make sure you get enough daily vitamins and minerals,
> get plenty of sleep and avoid stress,
>
> and take DHEA, Melatonin and HGH if you can afford it.
>
> Cheers!

Bored on Sat night Om? :-)

Yes, actually. ;-)
I'm going back and forth between the computer and the kitchen.
I'm making pork and shrimp fried rice. Done correctly, it's done in
steps so take time.

Quoted message said:

Here is a new one for you! PMID: 15919742 -

"administration of GH is often advocated as an "anti-aging" therapy.
In sharp contrast ... GH deficiency, GH resistance, and reduced IGF-I
signaling in mice are associated with symptoms of delayed aging and
markedly extended longevity. Although most normal mice
die at approximately 2 yr of age, hypopituitary and GH-resistant
mutants often survive beyond the age of 3 yr and occasionally past the
age of 4 yr, i.e. outside the range encountered in various laboratory
strains of this species."

When will I convince you?
HGH is a scam.

No, but only because I've seen what it's done for my 73 year old father.

Improved quality of life of an ill old person?

Do you have a problem with that?

Quoted message said:

So does morphine.

Yeah right. Morphine is good. NOT!!!
I won't even go into the number of reasons why.
I've studied up on opiates. They are insidious.

Mushrooms are better. ;-)

Quoted message said:

There is absolutely no evidence HGH has positive effect on longevity
and plenty of evidence it does the reverse.

Quality IMHO is better than quantity.
Time will tell.

Quoted message said:

Yeah, we're not mice is ALWAYS a good argument.

It's true.

Show me the same data on primate models and I'll consider it.

Cheers!
--
Om.

"My mother never saw the irony in calling me a son-of-a-[censored]." -Jack Nicholson

OmManiPadmeOmelet said:

DZ said:

Quoted message said:

> Here is a new one for you! PMID: 15919742 -
>
> "administration of GH is often advocated as an "anti-aging" therapy.
> In sharp contrast ... GH deficiency, GH resistance, and reduced IGF-I
> signaling in mice are associated with symptoms of delayed aging and
> markedly extended longevity. Although most normal mice
> die at approximately 2 yr of age, hypopituitary and GH-resistant
> mutants often survive beyond the age of 3 yr and occasionally past the
> age of 4 yr, i.e. outside the range encountered in various laboratory
> strains of this species."
>
> When will I convince you?
> HGH is a scam.

No, but only because I've seen what it's done for my 73 year old father.

Improved quality of life of an ill old person?

Do you have a problem with that?

With writing "longevity" in place of "quality of life", yes.

Quoted message said:

Quoted message said:

There is absolutely no evidence HGH has positive effect on longevity
and plenty of evidence it does the reverse.

Quality IMHO is better than quantity.
Time will tell.

Even "quality" is restricted to specific conditions, see below.

Quoted message said:

Quoted message said:

Yeah, we're not mice is ALWAYS a good argument.

It's true.
Show me the same data on primate models and I'll consider it.

How about humans?

Although studies in rodent models point to GH and IGF-I as promoters
of aging and age-related diseases, GH is prescribed extensively as an
antiaging hormone (1). [...] However, the "antiaging" effects of GH
therapy are typically observed after short-term treatment of patients
with low plasma GH. By contrast, chronically high GH levels increase
the incidence of diseases, including cancer and kidney diseases in
rodents, and increase cardiovascular diseases and cancer in human
acromegaly patients. GH administration also increases the development
of diabetes and glucose intolerance in healthy, older women and men
(1) and increases morbidity and mortality in patients that are
clinically ill, even after short-term treatment (2). It is clear that
a major and chronic increase in plasma GH/IGF-I levels increases
morbidity and mortality.

From Longo VD, Finch CE 2003 Evolutionary Medicine: From Dwarf Model
Systems to Healthy Centenarians? Science 299(5611): 1342-1346

[1] M.R. Blackman, et al., JAMA 288, 2282 (2002).
[2] J. Takala, et al., N. Engl. J. Med. 341, 785 (1999)