Quoted message said:
The trial will show if there is anything there, snipits of research here
and there we can't question in detail is not going to do it. All the self
reported "success" stories will not do it. Appeals to how mistreated
fringe doctors are by main stream research while regretable will not do
it. Science/medicine advances on multiple demonstrations of a good match
between theory and objective repeatble observations. In my mind the
following is the now accepted concensus and the benchmark by which such
questions should be approached. The asorbtion of pe from the gut has not
yet been demonstrated, and it remains questionable that any enzymes of any
size can, until that can be demonstrated and confirmed, the things shown
here are suggestive but not conclusive. In the list of problems with the
idea they can below, even if they are absorbed they are still subject to
destruction and can be themselves a source of immunity and other problems.
All of the problems must be addressed, but even they are mute if routine
normal absorbtion can not be demonstrated. We cann't tell about the
quality of the studies done on absorbtion are and how they might have
controlled for internal generation of enzymes. The pig example does
control to exclude internal generation and it specifically shows no
absorbtion of pe. Here are the main unanswered questions about the
proposed cancer treatment:
http://www.quackwatch.org/01QuackeryRelatedTopics/Cancer/kg.html
Glandular enzymes restoring normal function to poison-damaged organs.
Biological barriers to efficient absorption of proteolytic enzymes
into the systemic circulation are so formidable that oral delivery is
all but impossible [30,31]. Intestinal absorption of protein molecules
depends on their size and complexity, their sensitivity to hydrolysis
by host stomach acids and to host digestive enzymes, the capacity for
transport across the intestinal mucosa, their avoidance of recognition
as foreign by the immune system, and their destruction by the
reticuloendothelial system [32].
Like all dietary proteins, enzymes are dismantled into constituent
amino acids by host proteolytic enzymes in the gastrointestinal tract,
thus destroying their enzymatic activity. Should intact enzymes manage
to enter the circulation, they would still have to avoid denaturation
by serum proteolytic enzymes. They would have to be "smart" enough to
find the "poisoned target organ" or cancer cell before destroying
serum proteins and blood-vessel-wall structural proteins. If the
enzymes were to avoid those barriers, their repeated appearance in the
circulation would eventually give rise to severe hypersensitivity
reactions and anaphylaxis. There seem to be good reasons for the
evolutionary characteristic of preventing the absorption of
proteolytic enzymes from the gastrointestinal tract.
Conclusions
* Neither Kelley nor Gonzalez has identified proposed toxins in
processed food.
* Neither has evidence that abnormal protein molecules from
necrosing tumors are toxins or that they poison organs.
* Neither has evidence that the toxins poison oxidative metabolism.
* Neither has evidence that cancers thrive in an anaerobic
environment.
* Neither has shown that coffee enemas, megavitamin doses, and their
special diets inhibit the progress of cancer.
* Neither has produced evidence that a deficiency of pancreatic
digestive enzymes is related to the onset of cancer.
* Neither has produced evidence that enzymes from animal or
vegetable sources can replace enzymes in human organs.
* There is no evidence that ingested pancreatic enzymes seek out and
kill cancer cells.
* Neither has produced evidence that their regimens are more
effective than a placebo for cancer.