Whats with all the hype surrounding marginal gains in sports physiology? It seems like every coach and athlete is obsessed with shaving off a few seconds or ounces, but is this really the most effective way to improve performance? Id love to hear about some of the more unconventional scientific concepts that have been explored in the realm of endurance sports. For example, what about the role of mitochondrial function in fatigue resistance? Or the impact of gut microbiome on nutrient absorption and utilization? Are there any researchers out there pushing the boundaries of our understanding of human physiology and performance? Lets move beyond the tired old discussions of VO2 max and lactate threshold and explore some of the more cutting-edge ideas that could potentially revolutionize the way we approach training and competition.