Vitamin supplements not for everyone.

Just my 2$ Rich

'More ominously, antioxidants seemed to accelerate artery
narrowing in diabetic women carrying a pair of haptoglobin-2
genes. Women without diabetes, however, experienced no
negative effects from the antioxidants even if they carried
a double dose of haptoglobin-2.'

Maybe a long term mortality study would clear this up?

medicalnewstoday.comyouropinions.phpOpen ↗
ionid=3897

I thought that most heart attacks were caused by ruptures in
plaques, and not narrowing arteries? It didn't mention
plaques really, just narrowing of the arteries and concluded
that this increases risk of atherosclerosis? I'd ask do
people with more narrow arteries have higher risk of death
from heart attacks?

See :-

lef.orgfeaturedOpen ↗
articles/may2000_vitamin_c_01.html

At a meeting of the American Heart Association held on March
2, 2000, a presentation was made of an unpublished trial
indicating that those who consumed high amounts of vitamin C
supplements had increased carotid intima-media wall
thickening over an 18-month time period. 41 The doctors who
made this presentation described high amounts of vitamin C
as up to 500 mg a day. This presentation contradicts
previous published studies showing that vitamin C protects
against carotid atherosclerosis and intima-media wall
thickening. 42

Also see The new research may help clear up some of the
controversy surrounding the use of antioxidant vitamins in
patients with heart disease. Some previous studies suggest
that antioxidant doses can prevent the progress of
atherosclerosis, while the majority of studies have shown
there is no benefit from taking antioxidants. Other studies
suggest that the vitamins can actually speed up the course
of heart disease by interfering with blood cholesterol
levels and the effect of cholesterol lowering drugs.

Also

jbc.org7127Open ↗

What this is saying that that the concentration of ascorbic
acid (vitamin C) is proportional to inhibiting the enzyme
HMG-COA Reductase. This is the same effect that Lipitor and
Zocor have - and explains why vitamin c predictably reduces
cholesterol, so would it not be by the same argument that
these drugs would be dangerous in these diabetics?

Cheers

Anth

"Rich Shewmaker" <[email hidden]> wrote in message news:fJGdnYuGtOw5O_jdRVn-
[email hidden]...

Quoted message said:

Check out this new study that indicates that anti-
oxidant vitamin supplementation may actually be harmful
for some people.

eurekalert.orgasftOpen ↗
vgf032604.php

I thought Anth might be interested in this.

--Rich

Also if you have complaints about dosage and RDA, why take
more than the RDA ncbi.nlm.nih.govquery.Open ↗
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15029029
This hint at higher doses to treat diseases. I seem to
recall that the common argument is 'plasma concentration
peaks at whatever.' so why take more because it's wasted
etc. . Anth