General fitness, health and nutrition · Public discussion

Ultrasound

Started by Doe · · Last activity · 2 posts · 449 views

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General fitness, health and nutrition
Published
31 December 2003
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2 January 2004
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  1. Ultrasound Med Biol. 2003 Dec;29(12):1799-1803. Links

    Ultrasound-mediated release of iron from ferritin.

    Morrissey JM, Taylor KD, Gilman SD.

    Cavalier Discovery Incorporated, Mason, OH, USA

    We investigated the release of iron from ferritin in aqueous solutions exposed to high-frequency
    ultrasound (US). Our data suggests that superoxide produced as a result of ultrasonic cavitation
    acts as a reducing agent, enabling the release of iron from ferritin. We also found that the release
    of ferritin iron during US exposure is enhanced by the addition of 5-hydroxy-1,4-naphthoquinone. We
    hypothesize that this quinone is ultrasonically transformed into a semiquinone radical capable of
    directly and indirectly reducing Fe(3+) in ferritin to soluble Fe(2+). Our proposed mechanism for
    the release of iron from ferritin adds new insight to the synergistic effect of quinone-containing
    cancer drugs with US. (E-mail: [email hidden])

    PMID: 14698347 [PubMed - as supplied by publisher]

    --------------------------------------------------------------------------
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  2. [email hidden] (doe) wrote in news:20031231105828.14410.00002006
    @mb-m28.aol.com:

    Quoted message said:

    Ultrasound Med Biol. 2003 Dec;29(12):1799-1803. Links

    Ultrasound-mediated release of iron from ferritin.

    Morrissey JM, Taylor KD, Gilman SD.

    Cavalier Discovery Incorporated, Mason, OH, USA

    We investigated the release of iron from ferritin in aqueous solutions


    exposed

    Quoted message said:

    to high-frequency ultrasound (US). Our data suggests that superoxide


    produced

    Quoted message said:

    as a result of ultrasonic cavitation acts as a reducing agent, enabling


    the

    Quoted message said:

    release of iron from ferritin. We also found that the release of


    ferritin iron

    Quoted message said:

    during US exposure is enhanced by the addition of 5-hydroxy-1,4-


    naphthoquinone.

    Quoted message said:

    We hypothesize that this quinone is ultrasonically transformed into a semiquinone radical capable
    of directly and indirectly reducing Fe(3+)


    in

    Quoted message said:

    ferritin to soluble Fe(2+). Our proposed mechanism for the release of


    iron from

    Quoted message said:

    ferritin adds new insight to the synergistic effect of quinone-


    containing

    Quoted message said:

    cancer drugs with US. (E-mail: [email hidden])

    PMID: 14698347 [PubMed - as supplied by publisher]

    ------------------------------------------------------------------------


    --

    IIRC, cavitation would be quite harmful if done within the human body.
    The sound energy involved is quite high and would cause severe tissue
    damage.

    r

    --
    Nothing beats the bandwidth of a station wagon filled with DLT tapes.

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