General fitness, health and nutrition · Public discussion

Thyroid / impaired antioxidative factor balance

Started by Doe · · Last activity · 2 posts · 341 views

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General fitness, health and nutrition
Published
6 April 2004
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7 April 2004
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Doe
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  1. Clin Chem Lab Med. 2004 Feb;42(2):154-8. Links

    Antioxidants in patients with hyperthyroidism.

    Mayer L, Romic Z, Skreb F, Bacic-Vrca V, Cepelak I, Zanic-
    Grubisic T, Kirin M.

    Department of Laboratory Medicine, Dubrava University
    Hospital, Zagreb, Croatia. [email hidden]

    Hyperthyroidism is a hypermetabolic state accompanied by
    increased oxygen utilization, increased production of
    reactive oxygen species and consequentially measurable
    changes in antioxidative factors. Therefore, the activities
    of whole blood glutathione peroxidase (GPx) and erythrocyte
    superoxide dismutase (SOD), total antioxidant status (TAS)
    in serum and erythrocytes, and serum urate and transferrrin
    concentrations were determined in 70 women: 14 with newly
    diagnosed Graves' disease (group A); 28 with hyperthyroidism
    on therapy with methimazole (group B, divided into two
    subgroups, B1 and B2) and 28 healthy women (group C). In
    comparison with control group C, GPx activity was
    significantly decreased in all patient groups (p < 0.05),
    whereas SOD activity was significantly decreased in group A
    (p < .01) and significantly increased in group B (p < 0.01).
    In comparison with the control group, serum TAS activity was
    significantly decreased in group A, and erythrocyte TAS
    activity in all patient groups. Study results suggest that
    the impaired antioxidative factor balance leads to the
    development and presence of oxidative stress in women with
    hyperthyroidism. The severity of these alterations,
    considered contradictory by some authors, appears to depend
    on the use of therapy.

    PMID: 15061353 [PubMed - in process]

    ------------------------------------------------------------
    --------------
    ------

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  2. I know that you cant beat fresh, ripe fruit and veg, but
    what sort of supplements do people recommend to increase
    antioxidant intake? Im taking "phytaloe" which is basically
    an extract from lots of different fruit...anybody know if
    it? Any ideas of its efficacy? Any other suggestions?

    Vish [email hidden]

    "doe" <[email hidden]> wrote in message news:20040406123049.27471.00000786@mb-
    m12.aol.com...

    Quoted message said:

    Clin Chem Lab Med. 2004 Feb;42(2):154-8. Links

    Antioxidants in patients with hyperthyroidism.

    Mayer L, Romic Z, Skreb F, Bacic-Vrca V, Cepelak I, Zanic-
    Grubisic T,


    Kirin M.

    Quoted message said:


    Department of Laboratory Medicine, Dubrava University
    Hospital, Zagreb, Croatia. [email hidden]

    Hyperthyroidism is a hypermetabolic state accompanied by
    increased oxygen utilization, increased production of
    reactive oxygen species and consequentially measurable
    changes in antioxidative factors. Therefore,


    the

    Quoted message said:

    activities of whole blood glutathione peroxidase (GPx) and
    erythrocyte superoxide dismutase (SOD), total antioxidant
    status (TAS) in serum and erythrocytes, and serum urate
    and transferrrin concentrations were


    determined

    Quoted message said:

    in 70 women: 14 with newly diagnosed Graves' disease
    (group A); 28 with hyperthyroidism on therapy with
    methimazole (group B, divided into two subgroups, B1 and
    B2) and 28 healthy women (group C). In comparison with
    control group C, GPx activity was significantly decreased
    in all patient


    groups

    Quoted message said:

    (p < 0.05), whereas SOD activity was significantly
    decreased in group A (p


    <

    Quoted message said:

    .01) and significantly increased in group B (p < 0.01). In
    comparison


    with the

    Quoted message said:

    control group, serum TAS activity was significantly
    decreased in group A,


    and

    Quoted message said:

    erythrocyte TAS activity in all patient groups. Study
    results suggest that


    the

    Quoted message said:

    impaired antioxidative factor balance leads to the
    development and


    presence of

    Quoted message said:

    oxidative stress in women with hyperthyroidism. The
    severity of these alterations, considered contradictory by
    some authors, appears to depend


    on the

    Quoted message said:

    use of therapy.

    PMID: 15061353 [PubMed - in process]

    ----------------------------------------------------------
    ----------------
    ------

    Who loves ya. Tom Jesus Was A Vegetarian!
    jesuswasavegetarian.7h.comjesuswasavegetarian.7h.com Man Is A Herbivore!
    pages.ivillage.commanisaherbivore DEAD
    PEOPLE WALKING


    pages.ivillage.comdeadpeoplewalking

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