Road Cycling · Public discussion

There Is No Test For Exogenous Testosterone

Started by wimpyVO2 · · Last activity · 3 posts · 243 views

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Road Cycling
Published
5 August 2006
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6 August 2006
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wimpyVO2
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  1. There is no test that can isolate exogenous testosterone from natural
    testosterone. The IRMS test only reveals that metabolized testosterone
    in urine has a different carbon-13/carbon-12 ratio than normal.

    Literature supports exogenous testo will in fact alter C-13/C-12.
    However, it hasn't been shown that synthetic testo exclusively alters
    the C-13/C-12 ratio. Ingesting foods, medicine, etc., could also change
    the ratio. They don't test the actual testosterone, it's the metabolic
    byproducts that get tested, which means the C-13 can come from other
    organic sources. There is no absolute proof that synthetic testo is the
    agent that caused Floyd's C-13/C-12 to shift.

  2. Is there a way to determine how much is exogenous, whether or not synthetic?

    That is, if a minute amount, then could argue it came from food or other
    normal sources that we all would show some in our systems. If a lot, what
    ever that is, then can argue must be intentional.

    So, if we all have some, then the UCI/WADA folks could be playing on
    sensationalism, unless the test shows a lot compared to normal super clean
    athlete.

    "wimpyVO2" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    There is no test that can isolate exogenous testosterone from natural
    testosterone. The IRMS test only reveals that metabolized testosterone
    in urine has a different carbon-13/carbon-12 ratio than normal.

    Literature supports exogenous testo will in fact alter C-13/C-12.
    However, it hasn't been shown that synthetic testo exclusively alters
    the C-13/C-12 ratio. Ingesting foods, medicine, etc., could also change
    the ratio. They don't test the actual testosterone, it's the metabolic
    byproducts that get tested, which means the C-13 can come from other
    organic sources. There is no absolute proof that synthetic testo is the
    agent that caused Floyd's C-13/C-12 to shift.

  3. "Chris" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    Is there a way to determine how much is exogenous, whether or not
    synthetic?

    No.

    Quoted message said:

    That is, if a minute amount, then could argue it came from food or other
    normal sources that we all would show some in our systems. If a lot, what
    ever that is, then can argue must be intentional.

    It can also come from an old "column" being used to separate the constituate
    components of the urine. Normally the peaks of separation are fairly sharp,
    as a column ages the peaks spread and the preceeding and following peaks can
    bleed into the material under test and compromise it somewhat.

    Quoted message said:

    So, if we all have some, then the UCI/WADA folks could be playing on
    sensationalism, unless the test shows a lot compared to normal super clean
    athlete.

    Really GOOD scientists can make really good separations. The problem is that
    it is more art than science since you have to know the instruments you're
    using extremely well.

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