General fitness, health and nutrition · Public discussion

Re The Cholesterol Paradox.

Started by Nick · · Last activity · 1 post · 400 views

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General fitness, health and nutrition
Published
5 December 2003
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5 December 2003
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Nick
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  1. You are correct, MattLB. I meant to say inside arteries - interstitial space, not inside
    individual cells.

    MattLB posted:

    "While it's certainly true that cholesterol doesn't clog up the arteries like limescale clogs up
    water pipes, atherosclerosis *doesn't* occur in cells. The initial oxidised fatty deposits that
    start the process off occur in the extracellular spaces in the artery wall, between the
    endothelial and smooth muscle cells. White blood cells invade the artery wall to attack the fatty
    deposits and end up making it worse. A combination of increasing deposit of oxidised fat and
    smooth muscle cell proliferation follows, which causes a bulge in the artery wall that reduces the
    diameter of the artery."

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