Questions about STATINS

(Zee) said:

Dr. Beatrice Golomb answers questins about statins. Dr.
Golomb's CV: medicine.ucsd.edugolombOpen ↗

NOTE: Link at end of Golomb interview on POLYNEUROPATHY and
statins, symptoms of which include

facial weakness difficulty walking difficulty using the
arms and hands or legs and feet sensation changes (usually
of the arms and hands or legs and feet), such as pain,
burning, tingling, numbness, or decreased sensation
swallowing difficulty speech impairment loss of muscle
function or feeling in the muscles joint pain hoarseness or
changing voice fatigue

Beatrice A. Golomb, MD, PhD on Statin Drugs March 7, 2002

coloradohealthsite.orggoOpen ↗
lomb.html

On February 1, 2002, CHS posted a Patient Alert about
Statin Drugs. According to an article in the Wall St.
Journal, doctors and patients have noted several side
effects of the most widely prescribed drugs in the U.S. -
statins (some brand names are Lipitor, Zocor, and
Provachol). Common complaints of patients taking statins
include memory loss, personality changes, irritability, and
aching muscle pain. The article also noted that the
National Institutes of Health is in the midst of an
independent study that will subject statin drugs and their
side effects to scientific scrutiny.

Dr. Beatrice A. Golomb, MD, PhD, is the Principal
Investigator of the NIH study. Dr. Golomb is affiliated
with the University of California at San Diego. In this
interview, Dr. Golomb answers questions posed to her by
Janet Williams, Colorado HealthSite librarian.

Dr. Golomb asks that the users of CHS who are willing to
share their experience with statins, or complete a
questionnaire regarding their experience, should
contact her at [email hidden].

Question: We understand that cholesterol is a nutrient
which occurs naturally in the body and is essential for
cell functioning. How low should one's LDL-cholesterol
level be reduced before this nutrient is depleted? Is the
age of the patient relevant in determining the appropriate
level of LDL cholesterol?

more at url....

B'adant

[This has all been posted before...no matter...]

Would you kindly respond to the following statement by Dr.
Golomb (in her reply to the first question you quote above)

"Nonetheless, high blood levels of cholesterol do bear a
relation to heart disease risk; and statin drugs that lower
cholesterol reduce the risk of heart disease and stroke,
which are primary causes of death and disability,
respectively, in the US."

I look forward to your reply.

L.

(Zee) said:

Dr. Beatrice Golomb answers questins about statins. Dr.
Golomb's CV: medicine.ucsd.edugolombOpen ↗

NOTE: Link at end of Golomb interview on POLYNEUROPATHY and
statins, symptoms of which include

facial weakness difficulty walking difficulty using the
arms and hands or legs and feet sensation changes (usually
of the arms and hands or legs and feet), such as pain,
burning, tingling, numbness, or decreased sensation
swallowing difficulty speech impairment loss of muscle
function or feeling in the muscles joint pain hoarseness or
changing voice fatigue

Beatrice A. Golomb, MD, PhD on Statin Drugs March 7, 2002

coloradohealthsite.orggoOpen ↗
lomb.html

Anyone who reads the study "Statins and the Risk of
Polyneuropathy" (linked at the bottom of the interview)
conclusion will see:

Despite their findings, however, the authors remind us that
statins also have known benefits in protecting against
coronary artery disease. In fact, the authors tell us that
"the substantial protective effect of statins, particularly
on coronary artery disease, is well documented and by far
outweighs the potential risk of statin-induced
polyneuropathy."

How does this statement fit in with your view that everyone
suffers damage from statins. I'm confused and look forward
to your elucidation of this apparent dichotomy.

L

Quoted message said:

On February 1, 2002, CHS posted a Patient Alert about
Statin Drugs. According to an article in the Wall St.
Journal, doctors and patients have noted several side
effects of the most widely prescribed drugs in the U.S. -
statins (some brand names are Lipitor, Zocor, and
Provachol). Common complaints of patients taking statins
include memory loss, personality changes, irritability, and
aching muscle pain. The article also noted that the
National Institutes of Health is in the midst of an
independent study that will subject statin drugs and their
side effects to scientific scrutiny.

Dr. Beatrice A. Golomb, MD, PhD, is the Principal
Investigator of the NIH study. Dr. Golomb is affiliated
with the University of California at San Diego. In this
interview, Dr. Golomb answers questions posed to her by
Janet Williams, Colorado HealthSite librarian.

Dr. Golomb asks that the users of CHS who are willing to
share their experience with statins, or complete a
questionnaire regarding their experience, should
contact her at [email hidden].

Question: We understand that cholesterol is a nutrient
which occurs naturally in the body and is essential for
cell functioning. How low should one's LDL-cholesterol
level be reduced before this nutrient is depleted? Is the
age of the patient relevant in determining the appropriate
level of LDL cholesterol?

more at url....

B'adant

(Zee) said:

Dr. Beatrice Golomb answers questins about statins. Dr.
Golomb's CV: medicine.ucsd.edugolombOpen ↗

NOTE: Link at end of Golomb interview on POLYNEUROPATHY and
statins, symptoms of which include

facial weakness difficulty walking difficulty using the
arms and hands or legs and feet sensation changes (usually
of the arms and hands or legs and feet), such as pain,
burning, tingling, numbness, or decreased sensation
swallowing difficulty speech impairment loss of muscle
function or feeling in the muscles joint pain hoarseness or
changing voice fatigue

Beatrice A. Golomb, MD, PhD on Statin Drugs March 7, 2002

coloradohealthsite.orggoOpen ↗
lomb.html

On February 1, 2002, CHS posted a Patient Alert about
Statin Drugs. According to an article in the Wall St.
Journal, doctors and patients have noted several side
effects of the most widely prescribed drugs in the U.S. -
statins (some brand names are Lipitor, Zocor, and
Provachol). Common complaints of patients taking statins
include memory loss, personality changes, irritability, and
aching muscle pain. The article also noted that the
National Institutes of Health is in the midst of an
independent study that will subject statin drugs and their
side effects to scientific scrutiny.

Dr. Beatrice A. Golomb, MD, PhD, is the Principal
Investigator of the NIH study. Dr. Golomb is affiliated
with the University of California at San Diego. In this
interview, Dr. Golomb answers questions posed to her by
Janet Williams, Colorado HealthSite librarian.

Dr. Golomb asks that the users of CHS who are willing to
share their experience with statins, or complete a
questionnaire regarding their experience, should
contact her at [email hidden].

Question: We understand that cholesterol is a nutrient
which occurs naturally in the body and is essential for
cell functioning. How low should one's LDL-cholesterol
level be reduced before this nutrient is depleted? Is the
age of the patient relevant in determining the appropriate
level of LDL cholesterol?

more at url....

B'adant

Oh well, I guess I'm being ignored by Zee and Lohse.

Predictable, I suppose.

L.

...."the substantial protective effect of statins,
particularly on coronary artery disease, is well documented
and by far outweighs the potential risk of statin-induced
polyneuropathy."

Statins and Risk of Polyneuropathy: A Case-control Study, by
D. Gaist, MD, PhD; U. Jeppesen, MD, PhD; M. Andersen, MD,
PhD; L. A. Garcia Rodriguez, MD, MSc; J. Hallas, MD, PhD;
and S. H. Sindrup MD, PhD; Neurology, May 2002.

"...high blood levels of cholesterol do bear a relation to
heart disease risk; and statin drugs that lower
cholesterol reduce the risk of heart disease and stroke,
which are primary causes of death and disability,
respectively, in the US:

Beatrice A. Golomb, MD, PhD on Statin Drugs March 7,
2002 interview

listener said:

On 14 Apr 2004 10:02:07 -0700, [email hidden]

(Zee) said:

Dr. Beatrice Golomb answers questins about statins. Dr.
Golomb's CV: medicine.ucsd.edugolombOpen ↗

NOTE: Link at end of Golomb interview on POLYNEUROPATHY
and statins, symptoms of which include

facial weakness difficulty walking difficulty using the
arms and hands or legs and feet sensation changes
(usually of the arms and hands or legs and feet), such as
pain, burning, tingling, numbness, or decreased sensation
swallowing difficulty speech impairment loss of muscle
function or feeling in the muscles joint pain hoarseness
or changing voice fatigue

Beatrice A. Golomb, MD, PhD on Statin Drugs March 7, 2002

coloradohealthsite.orggoloOpen ↗
mb.html

On February 1, 2002, CHS posted a Patient Alert about
Statin Drugs. According to an article in the Wall St.
Journal, doctors and patients have noted several side
effects of the most widely prescribed drugs in the U.S. -
statins (some brand names are Lipitor, Zocor, and
Provachol). Common complaints of patients taking statins
include memory loss, personality changes, irritability,
and aching muscle pain. The article also noted that the
National Institutes of Health is in the midst of an
independent study that will subject statin drugs and
their side effects to scientific scrutiny.

Dr. Beatrice A. Golomb, MD, PhD, is the Principal
Investigator of the NIH study. Dr. Golomb is
affiliated with the University of California at San
Diego. In this interview, Dr. Golomb answers
questions posed to her by Janet Williams, Colorado
HealthSite librarian.

Dr. Golomb asks that the users of CHS who are willing to
share their experience with statins, or complete a
questionnaire regarding their experience, should
contact her at [email hidden].

Question: We understand that cholesterol is a nutrient
which occurs naturally in the body and is essential for
cell functioning. How low should one's LDL-cholesterol
level be reduced before this nutrient is depleted? Is the
age of the patient relevant in determining the
appropriate level of LDL cholesterol?

more at url....

B'adant

Oh well, I guess I'm being ignored by Zee and Lohse.

Predictable, I suppose.

L.

Not at all. I made my submission about 5 hours ago. As
our system has been slow due to spam-attack, perhaps
your provider's system has also slowed down due to
similar attack.

A.L.

Quoted message said:

...."the substantial protective effect of statins,
particularly on coronary artery disease, is well
documented and by far outweighs the potential risk of statin-
induced polyneuropathy."

Statins and Risk of Polyneuropathy: A Case-control Study,
by D. Gaist, MD, PhD; U. Jeppesen, MD, PhD; M. Andersen,
MD, PhD; L. A. Garcia Rodriguez, MD, MSc; J. Hallas, MD,
PhD; and S. H. Sindrup MD, PhD; Neurology, May 2002.

"...high blood levels of cholesterol do bear a relation to
heart disease risk; and statin drugs that lower
cholesterol reduce the risk of heart disease and stroke,
which are primary causes of death and disability,
respectively, in the US:

Beatrice A. Golomb, MD, PhD on Statin Drugs March 7, 2002
interview