I offer this information because I have been diagnosed with
NICO and want people to be aware of the profound impact this
condition can have on our health.
Maxillofacial Osteonecrosis(NICO) Published Abstracts,
Letters, Etc.
1. Demerath RR, Sist T. Treatment of osteocavitation
lesions in facial pain patients: preliminary results. J
Dent Res 1982; 61:218. (research abstract)
2. Raskin NH: Atypical facial pain. Proceedings of Annual
Meeting, American Association for the Study of Headache;
Quebec, Canada, June, 1987. (research abstract)
3. Bouquot JE, Roberts AM, Person, P, Christian J. The
histopathology of neuralgia-inducing cavitational
osteonecrosis (NICO). J Dent Res 1989;
3:1. (research abstract)
4. Bouquot J, Christian J. Long-term effects of
jawbone curettage on the pain of facial neuralgia;
treatment results in neuralgia-inducing
cavitational osteonecrosis. Oral Surg 1991; 72:582.
(research abstract)
5. McMahon RE, Griep J, Marfurt CP. Local anesthetic
effects in the presence of chronic osteomyelitis of
the mandible. J Orofacial Pain 1992; 7:116.
(research abstract)
6. McMahon RE, Griep J, Marfurt CP. Local anesthetic
effects in the presence of chronic osteomyelitis of the
mandible. Anesth Prog 1991; 38:189. (research abstract)
7. Donlon WC. Neuralgia-inducing cavitational
osteonecrosis. Oral Surg 1992;
8:319-320. (invited commentary)
9. Bouquot JE. More on neuralgia-inducing cavitational
osteonecrosis (NICO). Oral Surg 1992; 74:348-350.
(response to Donlon commentary)
10. Bouquot J, Roberts A. NICO (neuralgia-inducing
cavitational osteonecrosis): radiographic appearance of
the "invisible" osteomyelitis. Oral Surg 1992; 74:600.
(research abstract)
11. McMahon R, Bouquot J. Corticosteroid use and jawbone
osteonecrosis. J Facial Pain, 1993. (research abstract)
12. Bouquot J. In review of NICO (neuralgia-inducing
cavitational osteonecrosis), the invisible
"osteomyelitis" of the jaws. Proceedings of Parker
Mahan International Conference on Facial Pain. Pantke
Institute, Gainesville, Florida; April, 1994.
(invited review)
13. Bouquot JE. Ischemia and infarction of the jaws - the
"phantom" pain of NICO. J Craniomand Pract 1994; 12:138-
139. (invited guest editorial)
14. McMahon R, Bouquot J, Mahan P, Gremillion H. Elevated
serum peripheral nerve anti-myelin antibody titers in
atypical facial pain patients with NICO. J Orofacial
Pain 1994; 8:104. (research abstract)
15. Glueck CJ, McMahon RE, Bouquot JE, Stroop D, Tracy T,
Freiberg R, [censored] Y, Rabinovich B. The pathophysiology
of idiopathic osteonecrosis of the jaws: thrombophilia
and hypofibrinolysis. Proceedings of Annual Meeting,
American Association of Physiology; May, 1995.
(research abstract)
16. Bouquot JE, Byron M. Ischemic osteonecrosis of the jaws
-- histopathology of 2,867 samples from patients with
facial pain. Proceedings of Annual Meeting, American
Academy of Oral & Maxillofacial Pathology; Colorado
Springs; May, 1995. (research abstract)
17. Bouquot J, McMahon R, Glueck C. Risk factors in
'idiopathic' osteonecrosis of the jaws: seven of ten
NICO patients have hereditary clotting disorders.
Proceedings of Annual Meeting, American Academy of Oral
& Maxillofacial Pathology; Colorado Springs, Colorado;
May, 1995. (research abstract)
18. Bouquot J, Adams W, Spolnik K, McMahon R. G.V. Black's
forgotten disease; a necropsy report of ischemic
osteonecrosis of the jaws. Proceedings of Annual
Meeting, American Academy of Oral & Maxillofacial
Pathology; Colorado Springs, Colorado; May, 1995.
(research abstract)
19. Donlon WC: Discussion. J Oral Maxillofacial Surg 1995;
53:397-398. (invited commentary)
20. Sciubba JJ: Discussion. J Oral Maxillofacial Surg 1995;
53:398-399. (invited commentary)
21. Glueck CJ, McMahon RE, Bouquot JE, Rabinovich B.
Hypofibrinolysis and thrombophilia, pathophysiologic
etiologies of osteonecrosis of the jaws and atypical
facial neuralgia. J Orofacial Pain, 1995; 9:103.
(research abstract)
22. Glueck CJ, McMahon RE, Bouquot JE, Stroop D, Trent T,
Freiberg R, [censored]
S. Resistance to activated protein C, estrogens, and
osteonecrosis of the jaws. J Invest Med 1995; 43 (suppl):
234A. (research abstract)
22. Glueck CJ, Gruppo R, McMahon RE, Bouquot JE, Stroop D,
Becker A, Tracy T, [censored] P. Anticardiolipin antibodies
and osteonecrosis of the jaws. J Invest Med 1995; 43
(suppl 3): 459A. (research abstract)
23. Gruppo R, Glueck C, McMahon R, Bouquot J.
Anticardiolipin antibodies, thrombophilia and
hypofibrinolysis in Neuralgia-Inducing Cavitational
Osteonecrosis of jaw. J Oral Maxillofac Surg 1995;
53(suppl): 84-85. (research abstract)
24. McMahon R, Glueck C, Bouquot J, Rabinovich B. Protein C
disorders are risk factors for alveolar osteonecrosis
and chronic facial pain. J Oral Maxillofac Surg 1995;
53(suppl): 169-170. (research abstract)
25. Stewart J: RIIB (Residual Infection In Bone) Project
syllabus. Indianapolis, Indiana: Indiana University,
1985. (research protocol for extended microbiology,
histopathology, surgical therapy research)
26. Bouquot J, McMahon R. Ischemic osteonecrosis of the jaws
in 2,023 patients with facial pain. J Oral Pathol Med
1996; 25:271. (research abstract)
27. Bouquot JE, McMahon RE. Ischemic osteonecrosis in facial
pain syndromes. TMDiary 1996; 8:32-39. (invited review
in the News Journal of the American Academy of Head,
Neck and Facial Pain)
28. Bouquot JE, McMahon RE. Ischemic osteonecrosis in
facial pain syndromes. Part I: A review of NICO (neuralgia-
inducing cavitational osteonecrosis) based on
experience with more than 2,000 patients. Edition 5.3
Morgantown, West Virginia, The Maxillofacial Center;
1996; 1-19. (handout)
29. Glueck CJ, McMahon RE, Bouquot J, Tracy T, Seive-Smith
L, [censored] P. Treatment of thrombophilia and
hypofibrinolysis ameliorates osteonecrosis of the jaws.
J Investig Med 1996; 44:375. (research abstract)
30. Hammerschmidt DE. Thrombophilia: taking it on the jaw. J
Lab Clin Med 1996; 127:411-412. (editorial)
31. American Academy of Oral & Maxillofacial Pathology.
Ischemic osteonecrosis consistent with neuralgia-
inducing cavitational osteonecrosis (NICO). Annual
Continued Competency Assurance Examination. Chicago:
AAOMP, 1997. (review of clinicopathology of NICO
accompanying microscopic case as part of annual exam)
32. Bouquot JE, McMahon RE. Ischemic alveolar osteonecrosis
in 2,023 patients with chronic facial pain. J Orofacial
Pain 1997; 11:180. (research abstract)
33. Bouquot JE, McMahon RE. Ischemic osteonecrosis. Oral
Surg Oral Med Oral Pathol Oral Radiol Endod 1997; 84:229-
230. (letter editor)
34. Bouquot JE, McMahon RE. Ischemic osteonecrosis of the
jaws. Part II: Histopathologic review of NICO (neuralgia-
inducing cavitational osteonecrosis), based on
experience with more than 4,000 jawbone biopsy samples.
Edition 1.1. Morgantown, West Virginia, The
Maxillofacial Center; 1997; 1-22. (handout)
35. Bouquot JE, McMahon RE. Ischemic osteonecrosis in facial
pain syndromes. Proceedings of Annual Meeting, American
Academy of Head, Neck & Facial Pain; Boston,
Massachusetts, August, 1997. (invited review)
36. Bouquot JE, McMahon RE. Ischemic alveolar osteonecrosis
in 2,023 patients with chronic facial pain. J Orofacial
Pain 1997; 11:180. (research abstract)
37. Denucci DJ, Dionne RA, Chen CC, Meehan SC. SPECT bone
scanning in the diagnosis of chronic idiopathic jaw
pain. J Dent Res. 1997;76:237. (research abstract)
38. Glueck CJ, McMahon RE, Bouquot JE. The treatment of
thrombophilia and hypofibrinolysis ameliorates the pain
of osteonecrosis of the jaws. J Orofacial Pain 1997;
11:180. (research abstract)
39. Glueck CJ, McMahon RE, Triplett DA, Bouquot JE, [censored] P.
The mutant Factor V Leiden gene and thrombophilic
resistance to activated Protein C, a common (24%)
significant (P = .001) pathoetiology of osteonecrosis of
the jaws with chronic facial pain. J Orofacial Pain
1997; 11:179. (research abstract)
40. Haley B. Characterization and identification of chemical
toxicants isolated from cavitational material and
infected root canaled teeth: in situ testing of teeth
for toxicity and infection. Proceedings of Annual
Meeting, International Academy of Oral Medicine &
Toxicology; San Diego, California; April, 1997. (invited
research summary)
41. Hammerschmidt DE. Thrombophilic osteonecrosis: another
chapter. J Lab Clin Med 1997; 130:451-452. (editorial)
42. McMahon RE, Glueck CJ, Bouquot JE, Rabinovich B. Protein
C Disorders are risk factors for alveolar osteonecrosis
and chronic facial pain. J Orofacial Pain 1997; 11:179.
(research abstract)
43. McMahon RE, Glueck CJ, Bouquot JE, Triplett. The
prevalence of factor V Leiden and methylene-
tetrahydrofolate reductase (MTHFR) gene mutations in 87
patients with osteonecrosis of the jaws and chronic
facial pain. J Orofacial Pain 1997; 11:179-180.
(research abstract)
44. Freedman P, Reich, Steinlauf. NICO and anticoagulation
therapy. Oral Surg Oral Med Oral Pathol Oral Radiol
Endod 1998, in press. (letter to the editor)
45. Glueck CJ. NICO and anticoagulation therapy. Oral Surg
Oral Med Oral Pathol Oral Radiol Endod 1998, in press.
(response to Freedman's letter to the editor)
46.McMahon R, Bouquot J, Mahan P, Saxen M. Elevated anti-
myelin antibodies in patients with maxillofacial
osteonecrosis (NICO). J Oral Pathol Med 1998;
47:345-346. (research abstract)
48. Bouquot J, McMahon R. Bone marrow edema syndrome, new
disease or early presentation of ischemic osteonecrosis?
J Oral Pathol Med 1998; 27:346. (research abstract)
49. Bouquot J. Clinicopathology of NICO. Syllabus, 33rd
annual meeting, American Academy of Environmental
Medicine; Baltimore, Maryland; 1998. (invited review)
50. Elkins WE. Neuralgia-inducing cavitational
osteonecrosis: a case presentation. Oklahoma Dent J
1999; Spring:26-28.
51. Anderson Q. Osteonecrosis of the temporomandibular
joint: correlation of magnetic resonance imaging and
histology. J Oral Maxillofac Surg 1999;
51:1. (invited and very negative commentary to paper by
Larheim TA, et al)
52. Bouquot J, McMahon R. Bone marrow edema syndrome,
independent disease or early presentation of ischemic
osteonecrosis? Proceedings, Annual meeting, American
Academy of Oral & Maxillofacial Pathology; May, 2000;
Williamsburg, Virginia. (research abstract)
53. Bouquot J, McMahon R. The hollow tuberosity -
clinicopathologic review of 1057 biopsied cases. J Oral
Pathol Med 2000; in press. (research abstract)
54. Bouquot J, Wrobleski G, Fenton S. The most common
osteonecrosis? Prevalence of maxillofacial
osteonecrosis (MFO). J Oral Pathol Med 2000; in press.
(research abstract)