"In general all molecules of any protein species adapt to the same conformation called the native
state of the molecule..." says one text. This is due to its AA swequence. But this is a native state
with a specific temp range.
If the temperature goes higher, then the protein denatures and is destroyed. If back to lower
temperatures, the protein can anneal back to its native state and be active again. Thus if the
native state can be destroyed by heat and reformed to its native state by lowering the heat, then
isn't the temp. range of its native state a key component of its structure?
Thus IF temp changes and goes up, the protein is destroyed. Evolution stops on this species of
protein. (Unless lower temps that foster annealing)
IF temp changes and goes down, the protein is under selection pressure to survive by adapting to
that environmental change.
I suggest proteins have a wall of high temp that they cannot cross. (unless that temp lowers and
annealing takes place) And in lower temps, has selection pressure to adapt to the change in the
environment. And the most adapted protein is selected in the new environment.
Comment?
Tom Hendricks