Dr Chung .. if you please : )

x-no-archive: yes Do you still have my email address ?
if not .. holler if you need to answer anything
personally .. 'nita

[email hidden] wrote in part:

Quoted message said:

x-no-archive: yes goodness, my friend .. you are getting
popular .. if you don't mind..I couldn't get an answer to
this on the pharmacy newsgroup and I knew you'd know the
answer .. I've been prescribed a medication (Geodon) with a
terminal half-life of about 7 hours. And reaching peak
plasma concentrations in 6 to 8 hours. I *think* that the
1/2 life means that in 7 hours 1/2 the med has been
eliminated from the body ?? so,it would all be out in 14
hours ? any way..could you explain it to me in laymen's
terms ? I need to know all I can about this medication !
been doing research,but .. sure don't understand 99% of it
: ( all the best, as usual 'nita ... Houston !

I don't know anything about Geodon or the form of its
administration, but nearly all drugs follow first-order
kinetics, which would mean that if the serum half-life is 7
hours, half remains after 7 hours, and 25% remains after 14
hours. Every 7 hours removes half of what is present.
--
Jim Chinnis Warrenton, Virginia, USA

Jim Chinnis said:

[email hidden] wrote in part:

Quoted message said:

x-no-archive: yes goodness, my friend .. you are getting
popular .. if you don't mind..I couldn't get an answer to
this on the pharmacy newsgroup and I knew you'd know the
answer .. I've been prescribed a medication (Geodon) with
a terminal half-life of about 7 hours. And reaching peak
plasma concentrations in 6 to 8 hours. I *think* that the
1/2 life means that in 7 hours 1/2 the med has been
eliminated from the body ?? so,it would all be out in 14
hours ? any way..could you explain it to me in laymen's
terms ? I need to know all I can about this medication !
been doing research,but .. sure don't understand 99% of
it : ( all the best, as usual 'nita ... Houston !

I don't know anything about Geodon or the form of its
administration, but nearly all drugs follow first-order
kinetics, which would mean that if the serum half-life is
7 hours, half remains after 7 hours, and 25% remains after
14 hours. Every 7 hours removes half of what is present.
--
Jim Chinnis Warrenton, Virginia, USA

Would concur.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
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