Conjugated Linoleic Acid

Hi Adam:

Quoted message said:

Does anybody know -
* Does CLA participate in the chain-lengthening pathway?

What I have read is that CLA competes with omega 3 and omega 6 for the
elongase and desaturase enzymes for their change to longer chain fatty
acids.

Quoted message said:

* Does it generate eicosinoids? Do they have a different activity
than the other omega-6 eicosinoids?

Eicos is the Greek equivalent of 20 hence the name eicosanoids.

There is usually some CLA in milk products.

"Conclusions: CLA supplementation had an adverse effect on insulin and
glucose metabolism. Whereas CLA had positive effects on HDL metabolism
and fibrinogen, a therapeutic nutrient should not be associated with
potentially adverse effects on other clinical markers of type 2
diabetes." Source: Conjugated linoleic acid supplementation, insulin
sensitivity, and lipoprotein metabolism in patients with type 2 diabetes
mellitus - http://www.ajcn.org/cgi/content/abstract/80/4/887

The following article had quite a few subsequent articles citing it.
Isomer-Specific Antidiabetic Properties of Conjugated Linoleic Acid
http://diabetes.diabetesjournals.org/cgi/content/full/50/5/1149

High Wire search for CLA+Conjugated Linoleic Acid
http://tinyurl.com/5w9f5

Frank

On 14 Oct 2004 14:17:16 -0700, [email hidden] (Adam Becker

Sr) said:

"Liz" <[email hidden]> wrote in alt.support.diabetes

Quoted message said:

message :<Krwbd.2471$lp6.1513@okepread01>...

Quoted message said:

***What is CLA?

CLA is Conjugated Linoleic Acid. Fat (tallow, cream) from grass-fed
cattle is a major source.

Physically, it's an 18-carbon, omega-6 di-unsaturated fatty acid.
'Conjugated' means that the double bonds are closer together. That
is, usually in the omega-3/6 series, the C=C bonds are separated by a
methylene:
C=C-C-C=C-C-C=C etc
In the conjugated acids, the double bonds are closer together. Since
the linoleics have only two double bonds, that means
C-C-C-C-C-C=C-C=C-C-C-C-C-C-C-C-C-COOH.

Biologically, it's reported but not proven to be active in weight loss
and fighting cancer. See Ben Best for some literature citations of
the cancer work:
http://www.benbest.com/health/essfat.html#cancer

from the opening lines of the home page:

You have stumbled onto the home page of a life-extensionist and an
inveterate scribbler. I love life and I want to prolong it as much as
possible. I am intensely interested in almost everything. And I love
being able to eloquently put my thoughts and feelings into words.

proves this to be a scam artists web site.

Quoted message said:

or his CRAN archives for some of the weight loss cites
http://www.benbest.com/CRAN/cran_9803.html (search on 'conjugated'😉
If you google conjugated.linoleic you'll get a lot of Big Beef sites.

Does anybody know -
* Does CLA participate in the chain-lengthening pathway? That is,
does it get lengthened to C20/C22 and further desaturated? If so,
* Does it generate eicosinoids? Do they have a different activity
than the other omega-6 eicosinoids?

Adam Becker

Mâck©®
Type 1 since 1975
http://www.alt-support-diabetes.org
http://www.diabetic-talk.org
http://www.insulin-pumpers.org

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but is morally treasonable to the American public."

....Theodore Roosevelt

Have you heard of the NO-CARB Diet for 2004?

NO C-heney
NO A-shcroft
NO R-umsfeld
NO B-ush
And Absolutely NO Rice!

For the past several months, I have been taking about 4 grams of CLA a day,
with meals. I buy it at WalMart --a blue labelled bottle on sale at the vitamin
(supplement) aisle. The name brand is Tonalin. I take it for the missing
nutrients in it, but I notice that, there has been a subtle but noticeable
firming up of my arm muscles. Also, a very slight firming and flattening of my
belly muscles.

Again, I do not take this (as it seems to be marketed and targeted) as a "diet
aid", nor do I intentionally take CLA to increase muscle bulk. But, it has the
very slight ability to apparently convert fat mass over to muscle mass. That
is, as fat cells are reduced, muscle size very slightly firms and increases.

Try this suggestion: before beginning on a course of taking CLA, look over and
feel your body. Palpate the muscles on the backs of your upper arm (triceps)
and look and feel your belly. Over the course of a few months taking CLA, in
addition to whatever else you may note, begin to notice that your triceps are
noticeably firmer and more muscular. Also, your belly muscle lays just a bit
flatter.

Mack©® <[email hidden]> wrote in message news:<[email hidden]>...

Quoted message said:

from the opening lines of the home page:

You have stumbled onto the home page of a life-extensionist and an
inveterate scribbler. I love life and I want to prolong it as much as
possible. I am intensely interested in almost everything. And I love
being able to eloquently put my thoughts and feelings into words.

proves this to be a scam artists web site.

I'm not sure how that paragraph equates to scam artist.

And the linked page to info on EFA's is decent reading.

Clay T.