B-vitamins & once-a-day supplementation

Chad C. said:

Good morning folks,

How much more optimal is it to spread the supplementation
out to twice a day (say once in the morning & once in the
evening) vs. just one time (morning, presumably?),
assuming the total amount of B you get in the day remains
constant (i.e., one pill twice a day vs. two pills taken
simultaneously in the morning).

Since many vitamins are water soluble and little stored
within the body (C and most B's), it is certainly best to
spread them out so there is a constant supply available to
your body.

--Paul Wakfer

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"Chad C." <[email hidden]> wrote

Quoted message said:

How much more optimal is it to spread the supplementation
out to twice a day (say once in the morning & once in the
evening) vs. just one time (morning, presumably?),
assuming the total amount of B you get in the day remains
constant (i.e., one pill twice a day vs. two pills taken
simultaneously in the morning).

The relationship between the current length of a day (24
hours, or so) and human metabolism might be best taken as a
somewhat arbitrary one. Regarding B vitamins in particular,
in high daily doses they should be spread out throughout a
standard day since they apparently (judging by previous sci.life-
extension exchanges on the subject) achieve saturation
levels easily. In other words, doubling your morning dose
might have very little healthful effect compared with adding
a late-afternoon dose to your morning dose.

You might want to consider carrying a pill bottle (or
multiple pill bottles -- one for each dosing time -- or a
pill organizer device) around with you during the day so you
can dose more than twice a day. Setting an alarm to go off
for dosing time would complete this strategy.

On 30 Jun 2004 10:46:38 -0700, [email hidden] (Fuel Sentry)

Quoted message said:

You might want to consider carrying a pill bottle (or
multiple pill bottles -- one for each dosing time -- or a
pill organizer device) around with you during the day so
you can dose more than twice a day. Setting an alarm to go
off for dosing time would complete this strategy.

But why stop here? Do it right. Set your alarm for 3 a.m. so
that supplies don't get low in the middle of the night.
Better yet, carry around and hang by your bedside an i.v.
pack to ensure a continuous flow to your cells.

Richard Schulman (for email reply, remove the "-xyz" part)