I have been on 8 mg per day of Avandia for several years. In the last year or so I lost about 50 lbs (deliberately trying to use). My last hemoglobin A1C was 5.3. Based on this excellent test result, my doctor suggested that I try reducing the dose of Avandia to 4 mg. per day (by cutting the pills and taking half a pill per dayt) and monitor my blood sugar to see how I am doing. I remember when I first started taking Avandia, it took about 3-4 months before it became really effective. If the smaller dose is going to be less effective than the previous dose, how long does it usually take to see the difference?
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