General fitness, health and nutrition · Public discussion

50% develop arthropathy

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General fitness, health and nutrition
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9 April 2007
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9 April 2007
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  1. Hemochromatosis is called a form of .. erythrocytosis .. increased red
    blood cells.

    Showing .. again .. increased red blood cell production linked to
    arthritis .. and coincidentally .. hyperviscosity exists IN ..
    rheumatoid arthritis AND .. lupus .. and it seems ..
    **indistinguishable** .. FROM .. rheumatoid arthritis.

    "These patients had been treated for rheumatoid arthritis and other
    rheumatologic disorders over several years."

    Meaning .. 'they' .. screwed up.

    Erythrocytosis leads to hyperviscosity.

    Z Rheumatol. 1997 May-Jun;56(3):156-62. Links
    [Hemochromatosis arthropathy--an early manifestation of genetic
    hemochromatosis][Article in German]
    Gottschalk R, Neeck G, Wigand R, Vogtherr B, Kaltwasser JP.
    Medizinische Klinik III Hamato-/Onkologie, Rheumatologie,
    Infektiologie, Johann-Wolfgang-Goethe Universitat, Frankfurt am Main.

    Recent studies have shown a high frequency of genetic hemochromatosis
    in the Caucasian population. In addition, the well known organ
    involvement of genetic hemochromatosis was evident; more than 50% of
    patients develop a typical arthropathy which may result in severe
    physical disability. Among approximately 5000 patients referred to the
    rheumatology outpatient clinics of Bad Nauheim and Frankfurt with
    different rheumatologic diagnoses, 11 patients with typical signs of
    hemochromatotic arthropathy were identified. In none of those cases
    had the diagnosis "genetic hemochromatosis" been previously
    established. These patients had been treated for rheumatoid arthritis
    and other rheumatologic disorders over several years. All showed
    severe organ dysfunction due to iron overload, resulting in a reduced
    life expectancy. This investigation shows that knowledge of the
    typical signs of hemochromatotic arthropathy could lead to an earlier
    diagnosis of genetic hemochromatosis which is necessary to prevent the
    complications of iron overload in those patients.

    PMID: 9340956 [PubMed - indexed for MEDLINE]

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    Tom

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